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Results: 1 to 20 of 39

1.

The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43.

Liachko NF, McMillan PJ, Strovas TJ, Loomis E, Greenup L, Murrell JR, Ghetti B, Raskind MA, Montine TJ, Bird TD, Leverenz JB, Kraemer BC.

PLoS Genet. 2014 Dec 4;10(12):e1004803. doi: 10.1371/journal.pgen.1004803. eCollection 2014 Dec.

PMID:
25473830
[PubMed - in process]
Free PMC Article
2.

Protein kinase d isoforms differentially modulate cofilin-driven directed cell migration.

Döppler H, Bastea LI, Borges S, Spratley SJ, Pearce SE, Storz P.

PLoS One. 2014 May 19;9(5):e98090. doi: 10.1371/journal.pone.0098090. eCollection 2014.

PMID:
24840177
[PubMed - in process]
Free PMC Article
3.

Protein kinase D-mediated phosphorylation at Ser99 regulates localization of p21-activated kinase 4.

Bastea LI, Döppler H, Pearce SE, Durand N, Spratley SJ, Storz P.

Biochem J. 2013 Oct 15;455(2):251-60. doi: 10.1042/BJ20130281.

PMID:
23841590
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Protein Kinase Inhibitors CK59 and CID755673 Alter Primary Human NK Cell Effector Functions.

Scheiter M, Bulitta B, van Ham M, Klawonn F, König S, Jänsch L.

Front Immunol. 2013 Mar 18;4:66. doi: 10.3389/fimmu.2013.00066. eCollection 2013.

PMID:
23508354
[PubMed]
Free PMC Article
5.

Histamine induces activation of protein kinase D that mediates tissue factor expression and activity in human aortic smooth muscle cells.

Hao F, Wu DD, Xu X, Cui MZ.

Am J Physiol Heart Circ Physiol. 2012 Dec 1;303(11):H1344-52. doi: 10.1152/ajpheart.00500.2011. Epub 2012 Sep 21.

PMID:
23001835
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.

Onodera Y, Nam JM, Hashimoto A, Norman JC, Shirato H, Hashimoto S, Sabe H.

J Cell Biol. 2012 Jun 25;197(7):983-96. doi: 10.1083/jcb.201201065.

PMID:
22734003
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Inducible silencing of protein kinase D3 inhibits secretion of tumor-promoting factors in prostate cancer.

LaValle CR, Zhang L, Xu S, Eiseman JL, Wang QJ.

Mol Cancer Ther. 2012 Jul;11(7):1389-99. doi: 10.1158/1535-7163.MCT-11-0887. Epub 2012 Apr 24.

PMID:
22532599
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Design, Synthesis, and Biological Evaluation of PKD Inhibitors.

George KM, Frantz MC, Bravo-Altamirano K, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P.

Pharmaceutics. 2011;3(2):186-228. doi: 10.3390/pharmaceutics3020186.

PMID:
22267986
[PubMed]
Free PMC Article
9.

Protein kinase D regulates RhoA activity via rhotekin phosphorylation.

Pusapati GV, Eiseler T, Rykx A, Vandoninck S, Derua R, Waelkens E, Van Lint J, von Wichert G, Seufferlein T.

J Biol Chem. 2012 Mar 16;287(12):9473-83. doi: 10.1074/jbc.M112.339564. Epub 2012 Jan 6.

PMID:
22228765
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Sphingomyelin synthases regulate protein trafficking and secretion.

Subathra M, Qureshi A, Luberto C.

PLoS One. 2011;6(9):e23644. doi: 10.1371/journal.pone.0023644. Epub 2011 Sep 27.

PMID:
21980337
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Protein kinase D regulates cofilin activity through p21-activated kinase 4.

Spratley SJ, Bastea LI, Döppler H, Mizuno K, Storz P.

J Biol Chem. 2011 Sep 30;286(39):34254-61. doi: 10.1074/jbc.M111.259424. Epub 2011 Aug 9.

PMID:
21832093
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin.

Bossuyt J, Chang CW, Helmstadter K, Kunkel MT, Newton AC, Campbell KS, Martin JL, Bossuyt S, Robia SL, Bers DM.

J Biol Chem. 2011 Sep 23;286(38):33390-400. doi: 10.1074/jbc.M111.246447. Epub 2011 Jul 27.

PMID:
21795686
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Protein kinase Cδ mediates the activation of protein kinase D2 in platelets.

Bhavanasi D, Kim S, Goldfinger LE, Kunapuli SP.

Biochem Pharmacol. 2011 Oct 1;82(7):720-7. doi: 10.1016/j.bcp.2011.06.032. Epub 2011 Jun 28.

PMID:
21736870
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation.

Azoitei N, Kleger A, Schoo N, Thal DR, Brunner C, Pusapati GV, Filatova A, Genze F, Möller P, Acker T, Kuefer R, Van Lint J, Baust H, Adler G, Seufferlein T.

Neuro Oncol. 2011 Jul;13(7):710-24. doi: 10.1093/neuonc/nor084.

PMID:
21727210
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities.

Chen J, Giridhar KV, Zhang L, Xu S, Wang QJ.

Carcinogenesis. 2011 Aug;32(8):1198-206. doi: 10.1093/carcin/bgr113. Epub 2011 Jun 10.

PMID:
21665893
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Synthesis and Structure-Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase D.

Bravo-Altamirano K, George KM, Frantz MC, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P.

ACS Med Chem Lett. 2011 Feb 14;2(2):154-159.

PMID:
21617763
[PubMed]
Free PMC Article
17.

Protein kinase D2 is an essential regulator of murine myoblast differentiation.

Kleger A, Loebnitz C, Pusapati GV, Armacki M, Müller M, Tümpel S, Illing A, Hartmann D, Brunner C, Liebau S, Rudolph KL, Adler G, Seufferlein T.

PLoS One. 2011 Jan 27;6(1):e14599. doi: 10.1371/journal.pone.0014599.

PMID:
21298052
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Role of protein kinase D signaling in pancreatic cancer.

Guha S, Tanasanvimon S, Sinnett-Smith J, Rozengurt E.

Biochem Pharmacol. 2010 Dec 15;80(12):1946-54. doi: 10.1016/j.bcp.2010.07.002. Epub 2010 Jul 16. Review.

PMID:
20621068
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Protein kinase D as a potential new target for cancer therapy.

LaValle CR, George KM, Sharlow ER, Lazo JS, Wipf P, Wang QJ.

Biochim Biophys Acta. 2010 Dec;1806(2):183-92. doi: 10.1016/j.bbcan.2010.05.003. Epub 2010 May 24. Review.

PMID:
20580776
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility.

Lavalle CR, Bravo-Altamirano K, Giridhar KV, Chen J, Sharlow E, Lazo JS, Wipf P, Wang QJ.

BMC Chem Biol. 2010 May 5;10:5. doi: 10.1186/1472-6769-10-5.

PMID:
20444281
[PubMed]
Free PMC Article

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