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Results: 1 to 20 of 254

1.

Nutrient-sensing mechanisms and pathways.

Efeyan A, Comb WC, Sabatini DM.

Nature. 2015 Jan 15;517(7534):302-10. doi: 10.1038/nature14190. Review.

PMID:
25592535
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

tRNAs as antibiotic targets.

Chopra S, Reader J.

Int J Mol Sci. 2014 Dec 25;16(1):321-49. doi: 10.3390/ijms16010321.

PMID:
25547494
[PubMed - in process]
Free PMC Article
3.

The place of RNA in the origin and early evolution of the genetic machinery.

Wächtershäuser G.

Life (Basel). 2014 Dec 19;4(4):1050-91. doi: 10.3390/life4041050.

PMID:
25532530
[PubMed]
Free PMC Article
4.

Novel and unique domains in aminoacyl-tRNA synthetases from human fungal pathogens Aspergillus niger, Candida albicans and Cryptococcus neoformans.

Datt M, Sharma A.

BMC Genomics. 2014 Dec 5;15:1069. doi: 10.1186/1471-2164-15-1069.

PMID:
25479903
[PubMed - in process]
Free PMC Article
5.

Evolutionary and structural annotation of disease-associated mutations in human aminoacyl-tRNA synthetases.

Datt M, Sharma A.

BMC Genomics. 2014 Dec 4;15:1063. doi: 10.1186/1471-2164-15-1063.

PMID:
25476837
[PubMed - in process]
Free PMC Article
6.

Double-sieving-defective aminoacyl-tRNA synthetase causes protein mistranslation and affects cellular physiology and development.

Lu J, Bergert M, Walther A, Suter B.

Nat Commun. 2014 Nov 27;5:5650. doi: 10.1038/ncomms6650.

PMID:
25427601
[PubMed - in process]
Free PMC Article
7.

A minimalist mitochondrial threonyl-tRNA synthetase exhibits tRNA-isoacceptor specificity during proofreading.

Zhou XL, Ruan ZR, Wang M, Fang ZP, Wang Y, Chen Y, Liu RJ, Eriani G, Wang ED.

Nucleic Acids Res. 2014 Dec 16;42(22):13873-86. doi: 10.1093/nar/gku1218. Epub 2014 Nov 20.

PMID:
25414329
[PubMed - in process]
Free PMC Article
8.

Prediction of uridine modifications in tRNA sequences.

Panwar B, Raghava GP.

BMC Bioinformatics. 2014 Oct 2;15:326. doi: 10.1186/1471-2105-15-326.

PMID:
25272949
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Relaxed substrate specificity leads to extensive tRNA Mischarging by Streptococcus pneumoniae class I and Class II aminoacyl-tRNA synthetases.

Shepherd J, Ibba M.

MBio. 2014 Sep 9;5(5):e01656-14. doi: 10.1128/mBio.01656-14.

PMID:
25205097
[PubMed - in process]
Free PMC Article
10.

EF-P dependent pauses integrate proximal and distal signals during translation.

Elgamal S, Katz A, Hersch SJ, Newsom D, White P, Navarre WW, Ibba M.

PLoS Genet. 2014 Aug 21;10(8):e1004553. doi: 10.1371/journal.pgen.1004553. eCollection 2014 Aug.

PMID:
25144653
[PubMed - in process]
Free PMC Article
11.

Engineering the elongation factor Tu for efficient selenoprotein synthesis.

Haruna K, Alkazemi MH, Liu Y, Söll D, Englert M.

Nucleic Acids Res. 2014 Sep;42(15):9976-83. doi: 10.1093/nar/gku691. Epub 2014 Jul 26.

PMID:
25064855
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea.

Liu Y, Nakamura A, Nakazawa Y, Asano N, Ford KA, Hohn MJ, Tanaka I, Yao M, Söll D.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10520-5. doi: 10.1073/pnas.1411267111. Epub 2014 Jul 7.

PMID:
25002468
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Origin and evolution of glutamyl-prolyl tRNA synthetase WHEP domains reveal evolutionary relationships within Holozoa.

Ray PS, Fox PL.

PLoS One. 2014 Jun 26;9(6):e98493. doi: 10.1371/journal.pone.0098493. eCollection 2014.

PMID:
24968216
[PubMed - in process]
Free PMC Article
14.

Probing the global and local dynamics of aminoacyl-tRNA synthetases using all-atom and coarse-grained simulations.

Strom AM, Fehling SC, Bhattacharyya S, Hati S.

J Mol Model. 2014 May;20(5):2245. doi: 10.1007/s00894-014-2245-1. Epub 2014 May 9.

PMID:
24810463
[PubMed - in process]
Free PMC Article
15.

Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase.

Wu J, Fan Y, Ling J.

Nucleic Acids Res. 2014 Jun;42(10):6523-31. doi: 10.1093/nar/gku271. Epub 2014 Apr 17.

PMID:
24744241
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness.

Koh CY, Kim JE, Wetzel AB, de van der Schueren WJ, Shibata S, Ranade RM, Liu J, Zhang Z, Gillespie JR, Buckner FS, Verlinde CL, Fan E, Hol WG.

PLoS Negl Trop Dis. 2014 Apr 17;8(4):e2775. doi: 10.1371/journal.pntd.0002775. eCollection 2014 Apr.

PMID:
24743796
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Exploring the biological and chemical complexity of the ligases.

Holliday GL, Rahman SA, Furnham N, Thornton JM.

J Mol Biol. 2014 May 15;426(10):2098-111. doi: 10.1016/j.jmb.2014.03.008. Epub 2014 Mar 21. Review.

PMID:
24657765
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures.

Zhang X, Ling J, Barcia G, Jing L, Wu J, Barry BJ, Mochida GH, Hill RS, Weimer JM, Stein Q, Poduri A, Partlow JN, Ville D, Dulac O, Yu TW, Lam AT, Servattalab S, Rodriguez J, Boddaert N, Munnich A, Colleaux L, Zon LI, Söll D, Walsh CA, Nabbout R.

Am J Hum Genet. 2014 Apr 3;94(4):547-58. doi: 10.1016/j.ajhg.2014.03.003. Epub 2014 Mar 20.

PMID:
24656866
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes.

Diodato D, Ghezzi D, Tiranti V.

Int J Cell Biol. 2014;2014:787956. doi: 10.1155/2014/787956. Epub 2014 Feb 4. Review.

PMID:
24639874
[PubMed]
Free PMC Article
20.

Aminoacyl-tRNA synthetases as drug targets in eukaryotic parasites.

Pham JS, Dawson KL, Jackson KE, Lim EE, Pasaje CF, Turner KE, Ralph SA.

Int J Parasitol Drugs Drug Resist. 2013 Nov 11;4(1):1-13. doi: 10.1016/j.ijpddr.2013.10.001. eCollection 2014 Apr. Review.

PMID:
24596663
[PubMed]
Free PMC Article
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