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Results: 12

1.

Certain Diet and Lifestyle May Contribute to Islet β-cells Protection in Type-2 Diabetes via the Modulation of Cellular PI3K/AKT Pathway.

Kitagishi Y, Nakanishi A, Minami A, Asai Y, Yasui M, Iwaizako A, Suzuki M, Ono Y, Ogura Y, Matsuda S.

Open Biochem J. 2014 Nov 1;8:74-82. doi: 10.2174/1874091X01408010074. eCollection 2014.

PMID:
25400709
[PubMed]
Free PMC Article
2.

In intact islets interstitial GABA activates GABA(A) receptors that generate tonic currents in α-cells.

Jin Y, Korol SV, Jin Z, Barg S, Birnir B.

PLoS One. 2013 Jun 24;8(6):e67228. doi: 10.1371/journal.pone.0067228. Print 2013.

PMID:
23826240
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Coordinate changes in histone modifications, mRNA levels, and metabolite profiles in clonal INS-1 832/13 β-cells accompany functional adaptations to lipotoxicity.

Malmgren S, Spégel P, Danielsson AP, Nagorny CL, Andersson LE, Nitert MD, Ridderstråle M, Mulder H, Ling C.

J Biol Chem. 2013 Apr 26;288(17):11973-87. doi: 10.1074/jbc.M112.422527. Epub 2013 Mar 8.

PMID:
23476019
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Glucose intolerance and diabetes following antigen-specific insulitis in diabetes-susceptible "humanized" transgenic mice.

Elagin RB, Jaume JC.

Biochem Biophys Res Commun. 2010 Apr 23;395(1):99-103. doi: 10.1016/j.bbrc.2010.03.146. Epub 2010 Mar 27.

PMID:
20350527
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The role of immunomodulation therapy in autoimmune diabetes.

Ludvigsson J; Linköping Diabetes Immune Intervention Study Group.

J Diabetes Sci Technol. 2009 Mar 1;3(2):320-30. Review.

PMID:
20144363
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion.

Casimir M, Lasorsa FM, Rubi B, Caille D, Palmieri F, Meda P, Maechler P.

J Biol Chem. 2009 Sep 11;284(37):25004-14. doi: 10.1074/jbc.M109.015495. Epub 2009 Jul 7.

PMID:
19584051
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice.

Elagin RB, Balijepalli S, Diacovo MJ, Baekkeskov S, Jaume JC.

J Autoimmun. 2009 Aug;33(1):50-7. doi: 10.1016/j.jaut.2009.02.004. Epub 2009 Mar 16.

PMID:
19289270
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

GABA in the endocrine pancreas: its putative role as an islet cell paracrine-signalling molecule.

Franklin IK, Wollheim CB.

J Gen Physiol. 2004 Mar;123(3):185-90. Epub 2004 Feb 9. Review. No abstract available.

PMID:
14769848
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

Braun M, Wendt A, Birnir B, Broman J, Eliasson L, Galvanovskis J, Gromada J, Mulder H, Rorsman P.

J Gen Physiol. 2004 Mar;123(3):191-204. Epub 2004 Feb 9.

PMID:
14769845
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Conversion into GABA (gamma-aminobutyric acid) may reduce the capacity of L-glutamine as an insulin secretagogue.

Fernández-Pascual S, Mukala-Nsengu-Tshibangu A, Martín Del Río R, Tamarit-Rodríguez J.

Biochem J. 2004 May 1;379(Pt 3):721-9.

PMID:
14763900
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

GAD2 on chromosome 10p12 is a candidate gene for human obesity.

Boutin P, Dina C, Vasseur F, Dubois S, Corset L, Séron K, Bekris L, Cabellon J, Neve B, Vasseur-Delannoy V, Chikri M, Charles MA, Clement K, Lernmark A, Froguel P.

PLoS Biol. 2003 Dec;1(3):E68. Epub 2003 Nov 3.

PMID:
14691540
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell.

Maechler P, Wollheim CB.

J Physiol. 2000 Nov 15;529 Pt 1:49-56. Review.

PMID:
11080250
[PubMed - indexed for MEDLINE]
Free PMC Article
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