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Results: 1 to 20 of 85

1.

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells.

Hawley SA, Ross FA, Gowans GJ, Tibarewal P, Leslie NR, Hardie DG.

Biochem J. 2014 Apr 15;459(2):275-87. doi: 10.1042/BJ20131344.

PMID:
24467442
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W.

Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27.

PMID:
24161930
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Phosphorylation-mediated regulation of alternative splicing in cancer.

Naro C, Sette C.

Int J Cell Biol. 2013;2013:151839. doi: 10.1155/2013/151839. Epub 2013 Aug 28. Review.

PMID:
24069033
[PubMed]
Free PMC Article
4.

Profiling the substrate specificity of protein kinases by on-bead screening of peptide libraries.

Trinh TB, Xiao Q, Pei D.

Biochemistry. 2013 Aug 20;52(33):5645-55. doi: 10.1021/bi4008947. Epub 2013 Jul 24.

PMID:
23848432
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Akt-signal integration is involved in the differentiation of embryonal carcinoma cells.

Chen B, Xue Z, Yang G, Shi B, Yang B, Yan Y, Wang X, Han D, Huang Y, Dong W.

PLoS One. 2013 Jun 6;8(6):e64877. doi: 10.1371/journal.pone.0064877. Print 2013.

PMID:
23762260
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells.

Mohammad DK, Nore BF, Hussain A, Gustafsson MO, Mohamed AJ, Smith CI.

Mol Cell Biol. 2013 Aug;33(16):3214-26. doi: 10.1128/MCB.00247-13. Epub 2013 Jun 10.

PMID:
23754751
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma.

Reis-Sobreiro M, Roué G, Moros A, Gajate C, de la Iglesia-Vicente J, Colomer D, Mollinedo F.

Blood Cancer J. 2013 May 31;3:e118. doi: 10.1038/bcj.2013.15.

PMID:
23727661
[PubMed]
Free PMC Article
8.

Dynamic adipocyte phosphoproteome reveals that Akt directly regulates mTORC2.

Humphrey SJ, Yang G, Yang P, Fazakerley DJ, Stöckli J, Yang JY, James DE.

Cell Metab. 2013 Jun 4;17(6):1009-20. doi: 10.1016/j.cmet.2013.04.010. Epub 2013 May 16.

PMID:
23684622
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Quantitative analysis of global phosphorylation changes with high-resolution tandem mass spectrometry and stable isotopic labeling.

Kweon HK, Andrews PC.

Methods. 2013 Jun 15;61(3):251-9. doi: 10.1016/j.ymeth.2013.04.010. Epub 2013 Apr 21. Review.

PMID:
23611819
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity.

Shen D, Bai M, Tang R, Xu B, Ju X, Pestell RG, Achilefu S.

Sci Rep. 2013;3:1697. doi: 10.1038/srep01697.

PMID:
23603888
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Clk/STY (cdc2-like kinase 1) and Akt regulate alternative splicing and adipogenesis in 3T3-L1 pre-adipocytes.

Li P, Carter G, Romero J, Gower KM, Watson J, Patel NA, Cooper DR.

PLoS One. 2013;8(1):e53268. doi: 10.1371/journal.pone.0053268. Epub 2013 Jan 4.

PMID:
23308182
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Asymmetric dimethylarginine induces endothelial nitric-oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1.

Rafikov R, Rafikova O, Aggarwal S, Gross C, Sun X, Desai J, Fulton D, Black SM.

J Biol Chem. 2013 Mar 1;288(9):6212-26. doi: 10.1074/jbc.M112.423269. Epub 2012 Dec 19.

PMID:
23255608
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Screening nonspecific interactions of peptides without background interference.

Keefe AJ, Caldwell KB, Nowinski AK, White AD, Thakkar A, Jiang S.

Biomaterials. 2013 Mar;34(8):1871-7. doi: 10.1016/j.biomaterials.2012.11.014. Epub 2012 Dec 14.

PMID:
23246063
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

High-risk human papillomavirus E6 oncoproteins interact with 14-3-3ζ in a PDZ binding motif-dependent manner.

Boon SS, Banks L.

J Virol. 2013 Feb;87(3):1586-95. doi: 10.1128/JVI.02074-12. Epub 2012 Nov 21.

PMID:
23175360
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

An engineered lantipeptide synthetase serves as a general leader peptide-dependent kinase.

Thibodeaux GN, van der Donk WA.

Chem Commun (Camb). 2012 Nov 7;48(86):10615-7. doi: 10.1039/c2cc34138g.

PMID:
23001385
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Development of a peptidase-resistant substrate for single-cell measurement of protein kinase B activation.

Proctor A, Wang Q, Lawrence DS, Allbritton NL.

Anal Chem. 2012 Aug 21;84(16):7195-202. doi: 10.1021/ac301489d. Epub 2012 Aug 9.

PMID:
22881604
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Identifying protein kinase target preferences using mass spectrometry.

Douglass J, Gunaratne R, Bradford D, Saeed F, Hoffert JD, Steinbach PJ, Knepper MA, Pisitkun T.

Am J Physiol Cell Physiol. 2012 Oct 1;303(7):C715-27. doi: 10.1152/ajpcell.00166.2012. Epub 2012 Jun 20.

PMID:
22723110
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.

Madhunapantula SV, Mosca PJ, Robertson GP.

Cancer Biol Ther. 2011 Dec 15;12(12):1032-49. doi: 10.4161/cbt.12.12.18442. Epub 2011 Dec 15. Review.

PMID:
22157148
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Deciphering the Arginine-binding preferences at the substrate-binding groove of Ser/Thr kinases by computational surface mapping.

Ben-Shimon A, Niv MY.

PLoS Comput Biol. 2011 Nov;7(11):e1002288. doi: 10.1371/journal.pcbi.1002288. Epub 2011 Nov 17.

PMID:
22125489
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Dissecting phosphorylation networks: lessons learned from yeast.

Mok J, Zhu X, Snyder M.

Expert Rev Proteomics. 2011 Dec;8(6):775-86. doi: 10.1586/epr.11.64. Review.

PMID:
22087660
[PubMed - indexed for MEDLINE]
Free PMC Article

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