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Results: 10

1.

Dynamic dissociating homo-oligomers and the control of protein function.

Selwood T, Jaffe EK.

Arch Biochem Biophys. 2012 Mar 15;519(2):131-43. doi: 10.1016/j.abb.2011.11.020. Epub 2011 Dec 13. Review.

PMID:
22182754
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The morpheein model of allostery: evaluating proteins as potential morpheeins.

Jaffe EK, Lawrence SH.

Methods Mol Biol. 2012;796:217-31. doi: 10.1007/978-1-61779-334-9_12.

PMID:
22052493
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Allostery and the dynamic oligomerization of porphobilinogen synthase.

Jaffe EK, Lawrence SH.

Arch Biochem Biophys. 2012 Mar 15;519(2):144-53. doi: 10.1016/j.abb.2011.10.010. Epub 2011 Oct 19. Review.

PMID:
22037356
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pseudomonas aeruginosa porphobilinogen synthase assembly state regulators: hit discovery and initial SAR studies.

Reitz AB, Ramirez UD, Stith L, Du Y, Smith GR, Jaffe EK.

ARKIVOC. 2010 Jun;2010:175-188.

PMID:
21643541
[PubMed]
Free PMC Article
5.

Plastid-associated porphobilinogen synthase from Toxoplasma gondii: kinetic and structural properties validate therapeutic potential.

Shanmugam D, Wu B, Ramirez U, Jaffe EK, Roos DS.

J Biol Chem. 2010 Jul 16;285(29):22122-31. doi: 10.1074/jbc.M110.107243. Epub 2010 May 4.

PMID:
20442414
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.

Probing the oligomeric assemblies of pea porphobilinogen synthase by analytical ultracentrifugation.

Kokona B, Rigotti DJ, Wasson AS, Lawrence SH, Jaffe EK, Fairman R.

Biochemistry. 2008 Oct 7;47(40):10649-56. doi: 10.1021/bi801128d. Epub 2008 Sep 17.

PMID:
18795796
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Shape shifting leads to small-molecule allosteric drug discovery.

Lawrence SH, Ramirez UD, Tang L, Fazliyez F, Kundrat L, Markham GD, Jaffe EK.

Chem Biol. 2008 Jun;15(6):586-96. doi: 10.1016/j.chembiol.2008.04.012.

PMID:
18559269
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Synergistic substrate inhibition of ent-copalyl diphosphate synthase: a potential feed-forward inhibition mechanism limiting gibberellin metabolism.

Prisic S, Peters RJ.

Plant Physiol. 2007 May;144(1):445-54. Epub 2007 Mar 23.

PMID:
17384166
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Rhodobacter capsulatus porphobilinogen synthase, a high activity metal ion independent hexamer.

Bollivar DW, Clauson C, Lighthall R, Forbes S, Kokona B, Fairman R, Kundrat L, Jaffe EK.

BMC Biochem. 2004 Nov 22;5:17.

PMID:
15555082
[PubMed - indexed for MEDLINE]
Free PMC Article

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