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Items: 1 to 20 of 41


GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.

Martin B, Chadwick W, Janssens J, Premont RT, Schmalzigaug R, Becker KG, Lehrmann E, Wood WH, Zhang Y, Siddiqui S, Park SS, Cong WN, Daimon CM, Maudsley S.

Front Endocrinol (Lausanne). 2016 Jan 18;6:191. doi: 10.3389/fendo.2015.00191. eCollection 2015.


Regulators and Effectors of Arf GTPases in Neutrophils.

Gamara J, Chouinard F, Davis L, Aoudjit F, Bourgoin SG.

J Immunol Res. 2015;2015:235170. doi: 10.1155/2015/235170. Epub 2015 Nov 2. Review.


GIT2 deficiency attenuates concanavalin A-induced hepatitis in mice.

Hao YE, He DF, Yin RH, Chen H, Wang J, Wang SX, Zhan YQ, Ge CH, Li CY, Yu M, Yang XM.

FEBS Open Bio. 2015 Aug 11;5:688-704. doi: 10.1016/j.fob.2015.08.005. eCollection 2015.


αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor.

Kortüm F, Harms FL, Hennighausen N, Rosenberger G.

PLoS One. 2015 Jul 15;10(7):e0132737. doi: 10.1371/journal.pone.0132737. eCollection 2015.


Nuclear GIT2 is an ATM substrate and promotes DNA repair.

Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S.

Mol Cell Biol. 2015 Apr;35(7):1081-96. doi: 10.1128/MCB.01432-14. Epub 2015 Jan 20.


The GTPase-activating protein GIT2 protects against colitis by negatively regulating Toll-like receptor signaling.

Wei J, Wei C, Wang M, Qiu X, Li Y, Yuan Y, Jin C, Leng L, Wang J, Yang X, He F.

Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8883-8. doi: 10.1073/pnas.1309218111. Epub 2014 May 30.


Identification of two tyrosine residues required for the intramolecular mechanism implicated in GIT1 activation.

Totaro A, Astro V, Tonoli D, de Curtis I.

PLoS One. 2014 Apr 3;9(4):e93199. doi: 10.1371/journal.pone.0093199. eCollection 2014.


The Arf GAP AGAP2 interacts with β-arrestin2 and regulates β2-adrenergic receptor recycling and ERK activation.

Wu Y, Zhao Y, Ma X, Zhu Y, Patel J, Nie Z.

Biochem J. 2013 Jun 15;452(3):411-21. doi: 10.1042/BJ20121004.


The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis.

Wang X, Liao S, Nelson ER, Schmalzigaug R, Spurney RF, Guilak F, Premont RT, Gesty-Palmer D.

Biochem Biophys Res Commun. 2012 Aug 24;425(2):407-12. doi: 10.1016/j.bbrc.2012.07.111. Epub 2012 Jul 27.


GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats.

Chadwick W, Martin B, Chapter MC, Park SS, Wang L, Daimon CM, Brenneman R, Maudsley S.

PLoS One. 2012;7(5):e36975. doi: 10.1371/journal.pone.0036975. Epub 2012 May 14.


Acute activation of β2-adrenergic receptor regulates focal adhesions through βArrestin2- and p115RhoGEF protein-mediated activation of RhoA.

Ma X, Zhao Y, Daaka Y, Nie Z.

J Biol Chem. 2012 Jun 1;287(23):18925-36. doi: 10.1074/jbc.M112.352260. Epub 2012 Apr 12.


GRK2: multiple roles beyond G protein-coupled receptor desensitization.

Evron T, Daigle TL, Caron MG.

Trends Pharmacol Sci. 2012 Mar;33(3):154-64. doi: 10.1016/ Epub 2012 Jan 23. Review.


Arrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle.

Morris GE, Nelson CP, Brighton PJ, Standen NB, Challiss RA, Willets JM.

Am J Physiol Cell Physiol. 2012 Mar 1;302(5):C723-34. doi: 10.1152/ajpcell.00202.2011.. Epub 2011 Dec 7.


How to find your way through the thymus: a practical guide for aspiring T cells.

Dzhagalov I, Phee H.

Cell Mol Life Sci. 2012 Mar;69(5):663-82. doi: 10.1007/s00018-011-0791-6. Epub 2011 Aug 14. Review.


Regulation of thymocyte positive selection and motility by GIT2.

Phee H, Dzhagalov I, Mollenauer M, Wang Y, Irvine DJ, Robey E, Weiss A.

Nat Immunol. 2010 Jun;11(6):503-11. doi: 10.1038/ni.1868. Epub 2010 May 2.


Emerging role of paxillin-PKL in regulation of cell adhesion, polarity and migration.

Yu JA, Deakin NO, Turner CE.

Cell Adh Migr. 2010 Jul-Sep;4(3):342-7. Epub 2010 Jul 3.


Impaired spine formation and learning in GPCR kinase 2 interacting protein-1 (GIT1) knockout mice.

Menon P, Deane R, Sagare A, Lane SM, Zarcone TJ, O'Dell MR, Yan C, Zlokovic BV, Berk BC.

Brain Res. 2010 Mar 4;1317:218-26. doi: 10.1016/j.brainres.2009.11.084. Epub 2010 Jan 4.


The GIT-PIX complexes regulate the chemotactic response of rat basophilic leukaemia cells.

Gavina M, Za L, Molteni R, Pardi R, de Curtis I.

Biol Cell. 2010 Jan 14;102(4):231-44. doi: 10.1042/BC20090074.


Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.

Yu JA, Deakin NO, Turner CE.

Mol Biol Cell. 2009 Nov;20(22):4706-19. doi: 10.1091/mbc.E09-07-0548. Epub 2009 Sep 23.

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