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Items: 1 to 20 of 117


Insulin Signaling and Heart Failure.

Riehle C, Abel ED.

Circ Res. 2016 Apr 1;118(7):1151-69. doi: 10.1161/CIRCRESAHA.116.306206. Review.


Cardiovascular Action of Insulin in Health and Disease: Endothelial L-Arginine Transport and Cardiac Voltage-Dependent Potassium Channels.

Dubó S, Gallegos D, Cabrera L, Sobrevia L, Zúñiga L, González M.

Front Physiol. 2016 Mar 15;7:74. doi: 10.3389/fphys.2016.00074. eCollection 2016. Review.


Myozap Deficiency Promotes Adverse Cardiac Remodeling via Differential Regulation of Mitogen-activated Protein Kinase/Serum-response Factor and β-Catenin/GSK-3β Protein Signaling.

Rangrez AY, Eden M, Poyanmehr R, Kuhn C, Stiebeling K, Dierck F, Bernt A, Lüllmann-Rauch R, Weiler H, Kirchof P, Frank D, Frey N.

J Biol Chem. 2016 Feb 19;291(8):4128-43. doi: 10.1074/jbc.M115.689620. Epub 2015 Dec 30.


Long-Term Overexpression of Hsp70 Does Not Protect against Cardiac Dysfunction and Adverse Remodeling in a MURC Transgenic Mouse Model with Chronic Heart Failure and Atrial Fibrillation.

Bernardo BC, Sapra G, Patterson NL, Cemerlang N, Kiriazis H, Ueyama T, Febbraio MA, McMullen JR.

PLoS One. 2015 Dec 14;10(12):e0145173. doi: 10.1371/journal.pone.0145173. eCollection 2015.


Phosphoinositide dependent protein kinase 1 is required for exercise-induced cardiac hypertrophy but not the associated mitochondrial adaptations.

Noh J, Wende AR, Olsen CD, Kim B, Bevins J, Zhu Y, Zhang QJ, Riehle C, Abel ED.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):297-305. doi: 10.1016/j.yjmcc.2015.10.015. Epub 2015 Oct 22.


Phosphoinositide 3-kinase: friend and foe in cardiovascular disease.

Ghigo A, Li M.

Front Pharmacol. 2015 Aug 13;6:169. doi: 10.3389/fphar.2015.00169. eCollection 2015. Review.


Electrocardiographic Characterization of Cardiac Hypertrophy in Mice that Overexpress the ErbB2 Receptor Tyrosine Kinase.

Sysa-Shah P, Sørensen LL, Abraham MR, Gabrielson KL.

Comp Med. 2015 Aug;65(4):295-307.


PI3K Phosphorylation Is Linked to Improved Electrical Excitability in an In Vitro Engineered Heart Tissue Disease Model System.

Kana K, Song H, Laschinger C, Zandstra PW, Radisic M.

Tissue Eng Part A. 2015 Sep;21(17-18):2379-89. doi: 10.1089/ten.TEA.2014.0412. Epub 2015 Aug 7.


Differential Role of Leptin and Adiponectin in Cardiovascular System.

Ghantous CM, Azrak Z, Hanache S, Abou-Kheir W, Zeidan A.

Int J Endocrinol. 2015;2015:534320. doi: 10.1155/2015/534320. Epub 2015 May 3. Review.


Cross talk of the first-line defense TLRs with PI3K/Akt pathway, in preconditioning therapeutic approach.

Pourrajab F, Yazdi MB, Zarch MB, Zarch MB, Hekmatimoghaddam S.

Mol Cell Ther. 2015 May 30;3:4. doi: 10.1186/s40591-015-0041-7. eCollection 2015.


Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues.

Feric NT, Radisic M.

Adv Drug Deliv Rev. 2016 Jan 15;96:110-34. doi: 10.1016/j.addr.2015.04.019. Epub 2015 May 5. Review.


Pik3ip1 modulates cardiac hypertrophy by inhibiting PI3K pathway.

Song HK, Kim J, Lee JS, Nho KJ, Jeong HC, Kim J, Ahn Y, Park WJ, Kim do H.

PLoS One. 2015 Mar 31;10(3):e0122251. doi: 10.1371/journal.pone.0122251. eCollection 2015.


A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model.

Rahim S, Minas T, Hong SH, Justvig S, Çelik H, Kont YS, Han J, Kallarakal AT, Kong Y, Rudek MA, Brown ML, Kallakury B, Toretsky JA, Üren A.

PLoS One. 2014 Dec 5;9(12):e114260. doi: 10.1371/journal.pone.0114260. eCollection 2014.


Diet and sex modify exercise and cardiac adaptation in the mouse.

Konhilas JP, Chen H, Luczak E, McKee LA, Regan J, Watson PA, Stauffer BL, Khalpey ZI, Mckinsey TA, Horn T, LaFleur B, Leinwand LA.

Am J Physiol Heart Circ Physiol. 2015 Jan 15;308(2):H135-45. doi: 10.1152/ajpheart.00532.2014. Epub 2014 Nov 14.


Acquisition of a quantitative, stoichiometrically conserved ratiometric marker of maturation status in stem cell-derived cardiac myocytes.

Bedada FB, Chan SS, Metzger SK, Zhang L, Zhang J, Garry DJ, Kamp TJ, Kyba M, Metzger JM.

Stem Cell Reports. 2014 Oct 14;3(4):594-605. doi: 10.1016/j.stemcr.2014.07.012. Epub 2014 Sep 4.


The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.

Carnero A, Paramio JM.

Front Oncol. 2014 Sep 23;4:252. doi: 10.3389/fonc.2014.00252. eCollection 2014. Review.


Abnormal calcium handling and exaggerated cardiac dysfunction in mice with defective vitamin d signaling.

Choudhury S, Bae S, Ke Q, Lee JY, Singh SS, St-Arnaud R, Monte FD, Kang PM.

PLoS One. 2014 Sep 30;9(9):e108382. doi: 10.1371/journal.pone.0108382. eCollection 2014.


Both GPER and membrane oestrogen receptor-α activation protect ventricular remodelling in 17β oestradiol-treated ovariectomized infarcted rats.

Lee TM, Lin SZ, Chang NC.

J Cell Mol Med. 2014 Dec;18(12):2454-65. doi: 10.1111/jcmm.12430. Epub 2014 Sep 25.


A neonatal blueprint for cardiac regeneration.

Porrello ER, Olson EN.

Stem Cell Res. 2014 Nov;13(3 Pt B):556-70. doi: 10.1016/j.scr.2014.06.003. Epub 2014 Jul 9. Review.


Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.

Riehle C, Wende AR, Zhu Y, Oliveira KJ, Pereira RO, Jaishy BP, Bevins J, Valdez S, Noh J, Kim BJ, Moreira AB, Weatherford ET, Manivel R, Rawlings TA, Rech M, White MF, Abel ED.

Mol Cell Biol. 2014 Sep 15;34(18):3450-60. doi: 10.1128/MCB.00426-14. Epub 2014 Jul 7.

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