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Items: 18


Eukaryotic Translation Initiation Factor 4E Is a Feed-Forward Translational Coactivator of Transforming Growth Factor β Early Protransforming Events in Breast Epithelial Cells.

Decarlo L, Mestel C, Barcellos-Hoff MH, Schneider RJ.

Mol Cell Biol. 2015 Aug;35(15):2597-609. doi: 10.1128/MCB.00324-15. Epub 2015 May 18.


Resistance to EGFR-TKI can be mediated through multiple signaling pathways converging upon cap-dependent translation in EGFR-wild type NSCLC.

Patel MR, Jay-Dixon J, Sadiq AA, Jacobson BA, Kratzke RA.

J Thorac Oncol. 2013 Sep;8(9):1142-7. doi: 10.1097/JTO.0b013e31829ce963.


Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype.

Issaenko OA, Bitterman PB, Polunovsky VA, Dahlberg PS.

Cancer Gene Ther. 2012 Sep;19(9):609-18. doi: 10.1038/cgt.2012.39. Epub 2012 Jul 6.


Niacin protects against UVB radiation-induced apoptosis in cultured human skin keratinocytes.

Lin F, Xu W, Guan C, Zhou M, Hong W, Fu L, Liu D, Xu A.

Int J Mol Med. 2012 Apr;29(4):593-600. doi: 10.3892/ijmm.2012.886. Epub 2012 Jan 12.


Understanding and Targeting the Eukaryotic Translation Initiation Factor eIF4E in Head and Neck Cancer.

Culjkovic B, Borden KL.

J Oncol. 2009;2009:981679. doi: 10.1155/2009/981679. Epub 2009 Dec 13.


Tumorigenic activity and therapeutic inhibition of Rheb GTPase.

Mavrakis KJ, Zhu H, Silva RL, Mills JR, Teruya-Feldstein J, Lowe SW, Tam W, Pelletier J, Wendel HG.

Genes Dev. 2008 Aug 15;22(16):2178-88. doi: 10.1101/gad.1690808.


Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.

Bordeleau ME, Robert F, Gerard B, Lindqvist L, Chen SM, Wendel HG, Brem B, Greger H, Lowe SW, Porco JA Jr, Pelletier J.

J Clin Invest. 2008 Jul;118(7):2651-60. doi: 10.1172/JCI34753.


The eIF4E RNA regulon promotes the Akt signaling pathway.

Culjkovic B, Tan K, Orolicki S, Amri A, Meloche S, Borden KL.

J Cell Biol. 2008 Apr 7;181(1):51-63. doi: 10.1083/jcb.200707018.


Dissecting eIF4E action in tumorigenesis.

Wendel HG, Silva RL, Malina A, Mills JR, Zhu H, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Teruya-Feldstein J, Pelletier J, Lowe SW.

Genes Dev. 2007 Dec 15;21(24):3232-7. Epub 2007 Nov 30.


Rapid turnover of mcl-1 couples translation to cell survival and apoptosis.

Adams KW, Cooper GM.

J Biol Chem. 2007 Mar 2;282(9):6192-200. Epub 2007 Jan 2.


mTOR-independent translational control of the extrinsic cell death pathway by RalA.

Panner A, Nakamura JL, Parsa AT, Rodriguez-Viciana P, Berger MS, Stokoe D, Pieper RO.

Mol Cell Biol. 2006 Oct;26(20):7345-57. Epub 2006 Aug 7.


Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI.

Zakowicz H, Yang HS, Stark C, Wlodawer A, Laronde-Leblanc N, Colburn NH.

RNA. 2005 Mar;11(3):261-74. Epub 2005 Jan 20.


Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency.

Li S, Sonenberg N, Gingras AC, Peterson M, Avdulov S, Polunovsky VA, Bitterman PB.

Mol Cell Biol. 2002 Apr;22(8):2853-61.


Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38.

Wolfman JC, Palmby T, Der CJ, Wolfman A.

Mol Cell Biol. 2002 Mar;22(5):1589-606.

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