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Items: 11


The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1.

Wang H, Chen Y, Lin P, Li L, Zhou G, Liu G, Logsdon C, Jin J, Abbruzzese JL, Tan TH, Wang H.

J Biol Chem. 2014 Feb 14;289(7):4009-17. doi: 10.1074/jbc.M113.520106. Epub 2013 Dec 20.


N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress.

Gray JJ, Zommer AE, Bouchard RJ, Duval N, Blackstone C, Linseman DA.

Brain Res. 2013 Feb 4;1494:28-43. doi: 10.1016/j.brainres.2012.12.001. Epub 2012 Dec 7.


Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein.

Wang X, Li JP, Chiu LL, Lan JL, Chen DY, Boomer J, Tan TH.

J Biol Chem. 2012 Oct 5;287(41):34091-100. doi: 10.1074/jbc.M112.371062. Epub 2012 Aug 17.


Down-regulation of B cell receptor signaling by hematopoietic progenitor kinase 1 (HPK1)-mediated phosphorylation and ubiquitination of activated B cell linker protein (BLNK).

Wang X, Li JP, Kuo HK, Chiu LL, Dement GA, Lan JL, Chen DY, Yang CY, Hu H, Tan TH.

J Biol Chem. 2012 Mar 30;287(14):11037-48. doi: 10.1074/jbc.M111.310946. Epub 2012 Feb 10.


Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor.

Denda K, Nakao-Wakabayashi K, Okamoto N, Kitamura N, Ryu JY, Tagawa Y, Ichisaka T, Yamanaka S, Komada M.

J Biol Chem. 2011 Aug 19;286(33):28802-10. doi: 10.1074/jbc.M111.258160. Epub 2011 Jun 29.


Caspases and kinases in a death grip.

Kurokawa M, Kornbluth S.

Cell. 2009 Sep 4;138(5):838-54. doi: 10.1016/j.cell.2009.08.021. Review.


Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer.

Wang H, Song X, Logsdon C, Zhou G, Evans DB, Abbruzzese JL, Hamilton SR, Tan TH, Wang H.

Cancer Res. 2009 Feb 1;69(3):1063-70. doi: 10.1158/0008-5472.CAN-08-1751. Epub 2009 Jan 13.


Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity.

Salmena L, Lemmers B, Hakem A, Matysiak-Zablocki E, Murakami K, Au PY, Berry DM, Tamblyn L, Shehabeldin A, Migon E, Wakeham A, Bouchard D, Yeh WC, McGlade JC, Ohashi PS, Hakem R.

Genes Dev. 2003 Apr 1;17(7):883-95. Epub 2003 Mar 21.


Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation.

Ura S, Masuyama N, Graves JD, Gotoh Y.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10148-53. Epub 2001 Aug 21.

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