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Results: 1 to 20 of 51

1.

Is non-homologous end-joining really an inherently error-prone process?

Bétermier M, Bertrand P, Lopez BS.

PLoS Genet. 2014 Jan;10(1):e1004086. doi: 10.1371/journal.pgen.1004086. Epub 2014 Jan 16. Review.

PMID:
24453986
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Understanding the loss-of-function in a triple missense mutant of DNA polymerase β found in prostate cancer.

An C, Beard WA, Chen D, Wilson SH, Makridakis NM.

Int J Oncol. 2013 Oct;43(4):1131-40. doi: 10.3892/ijo.2013.2022. Epub 2013 Jul 19.

PMID:
23877444
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Yeast pol4 promotes tel1-regulated chromosomal translocations.

Ruiz JF, Pardo B, Sastre-Moreno G, Aguilera A, Blanco L.

PLoS Genet. 2013;9(7):e1003656. doi: 10.1371/journal.pgen.1003656. Epub 2013 Jul 18.

PMID:
23874240
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Evidence for abasic site sugar phosphate-mediated cytotoxicity in alkylating agent treated Saccharomyces cerevisiae.

Heacock M, Poltoratsky V, Prasad R, Wilson SH.

PLoS One. 2012;7(10):e47945. doi: 10.1371/journal.pone.0047945. Epub 2012 Oct 29.

PMID:
23144716
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

DNA-binding determinants promoting NHEJ by human Polμ.

Martin MJ, Juarez R, Blanco L.

Nucleic Acids Res. 2012 Dec;40(22):11389-403. doi: 10.1093/nar/gks896. Epub 2012 Oct 2.

PMID:
23034807
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mechanisms of chromosome number evolution in yeast.

Gordon JL, Byrne KP, Wolfe KH.

PLoS Genet. 2011 Jul;7(7):e1002190. doi: 10.1371/journal.pgen.1002190. Epub 2011 Jul 21.

PMID:
21811419
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes.

Li T, Huang S, Zhao X, Wright DA, Carpenter S, Spalding MH, Weeks DP, Yang B.

Nucleic Acids Res. 2011 Aug;39(14):6315-25. doi: 10.1093/nar/gkr188. Epub 2011 Mar 31.

PMID:
21459844
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Systematic biochemical analysis of somatic missense mutations in DNA polymerase β found in prostate cancer reveal alteration of enzymatic function.

An CL, Chen D, Makridakis NM.

Hum Mutat. 2011 Apr;32(4):415-23. doi: 10.1002/humu.21465. Epub 2011 Mar 1.

PMID:
21305655
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

End-processing during non-homologous end-joining: a role for exonuclease 1.

Bahmed K, Seth A, Nitiss KC, Nitiss JL.

Nucleic Acids Res. 2011 Feb;39(3):970-8. doi: 10.1093/nar/gkq886. Epub 2010 Oct 8.

PMID:
20935051
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Collaboration and competition between DNA double-strand break repair pathways.

Kass EM, Jasin M.

FEBS Lett. 2010 Sep 10;584(17):3703-8. doi: 10.1016/j.febslet.2010.07.057. Epub 2010 Aug 5. Review.

PMID:
20691183
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Polymerases in nonhomologous end joining: building a bridge over broken chromosomes.

Ramsden DA.

Antioxid Redox Signal. 2011 Jun 15;14(12):2509-19. doi: 10.1089/ars.2010.3429. Epub 2010 Oct 28. Review.

PMID:
20649463
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair.

Daley JM, Wilson TE, Ramotar D.

DNA Repair (Amst). 2010 Jun 4;9(6):690-9. doi: 10.1016/j.dnarep.2010.03.006. Epub 2010 Apr 15.

PMID:
20399152
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.

Lieber MR.

Annu Rev Biochem. 2010;79:181-211. doi: 10.1146/annurev.biochem.052308.093131. Review.

PMID:
20192759
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Yeast Tdp1 regulates the fidelity of nonhomologous end joining.

Bahmed K, Nitiss KC, Nitiss JL.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4057-62. doi: 10.1073/pnas.0909917107. Epub 2010 Feb 16.

PMID:
20160111
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans.

Lieber MR, Gu J, Lu H, Shimazaki N, Tsai AG.

Subcell Biochem. 2010;50:279-96. doi: 10.1007/978-90-481-3471-7_14. Review.

PMID:
20012587
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

MLH1 deficiency enhances tumor cell sensitivity to ganciclovir.

O'Konek JJ, Boucher PD, Iacco AA, Wilson TE, Shewach DS.

Cancer Gene Ther. 2009 Sep;16(9):683-92. doi: 10.1038/cgt.2009.16. Epub 2009 Mar 20.

PMID:
19300472
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Role of budding yeast Rad18 in repair of HO-induced double-strand breaks.

Hirano Y, Reddy J, Sugimoto K.

DNA Repair (Amst). 2009 Jan 1;8(1):51-9. doi: 10.1016/j.dnarep.2008.08.013. Epub 2008 Oct 11.

PMID:
18824138
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Genomic analysis of cancer tissue reveals that somatic mutations commonly occur in a specific motif.

Makridakis NM, Caldas Ferraz LF, Reichardt JK.

Hum Mutat. 2009 Jan;30(1):39-48. doi: 10.1002/humu.20810.

PMID:
18623241
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Proofreading activity of DNA polymerase Pol2 mediates 3'-end processing during nonhomologous end joining in yeast.

Tseng SF, Gabriel A, Teng SC.

PLoS Genet. 2008 Apr 25;4(4):e1000060. doi: 10.1371/journal.pgen.1000060.

PMID:
18437220
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Evidence that base stacking potential in annealed 3' overhangs determines polymerase utilization in yeast nonhomologous end joining.

Daley JM, Wilson TE.

DNA Repair (Amst). 2008 Jan 1;7(1):67-76. Epub 2007 Sep 18.

PMID:
17881298
[PubMed - indexed for MEDLINE]
Free PMC Article

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