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The negatively charged carboxy-terminal tail of β-tubulin promotes proper chromosome segregation.

Fees CP, Aiken J, O'Toole ET, Giddings TH Jr, Moore JK.

Mol Biol Cell. 2016 Jun 1;27(11):1786-96. doi: 10.1091/mbc.E15-05-0300. Epub 2016 Apr 6.


Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors.

Woodford MR, Truman AW, Dunn DM, Jensen SM, Cotran R, Bullard R, Abouelleil M, Beebe K, Wolfgeher D, Wierzbicki S, Post DE, Caza T, Tsutsumi S, Panaretou B, Kron SJ, Trepel JB, Landas S, Prodromou C, Shapiro O, Stetler-Stevenson WG, Bourboulia D, Neckers L, Bratslavsky G, Mollapour M.

Cell Rep. 2016 Feb 2;14(4):872-84. doi: 10.1016/j.celrep.2015.12.084. Epub 2016 Jan 21.


The composition, functions, and regulation of the budding yeast kinetochore.

Biggins S.

Genetics. 2013 Aug;194(4):817-46. doi: 10.1534/genetics.112.145276. Review.


Meiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions.

Miller MP, Unal E, Brar GA, Amon A.

Elife. 2012 Dec 18;1:e00117. doi: 10.7554/eLife.00117.


Loss of function of the Cik1/Kar3 motor complex results in chromosomes with syntelic attachment that are sensed by the tension checkpoint.

Jin F, Liu H, Li P, Yu HG, Wang Y.

PLoS Genet. 2012 Feb;8(2):e1002492. doi: 10.1371/journal.pgen.1002492. Epub 2012 Feb 2.


Visualizing kinetochore architecture.

Alushin G, Nogales E.

Curr Opin Struct Biol. 2011 Oct;21(5):661-9. doi: 10.1016/ Epub 2011 Aug 22. Review.


Cryo-EM studies of microtubule structural intermediates and kinetochore-microtubule interactions.

Nogales E, Ramey VH, Wang HW.

Methods Cell Biol. 2010;95:129-56. doi: 10.1016/S0091-679X(10)95008-5. Review.


Structure-function insights into the yeast Dam1 kinetochore complex.

Nogales E, Ramey VH.

J Cell Sci. 2009 Nov 1;122(Pt 21):3831-6. doi: 10.1242/jcs.004689. Review.


Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase.

Shimogawa MM, Graczyk B, Gardner MK, Francis SE, White EA, Ess M, Molk JN, Ruse C, Niessen S, Yates JR 3rd, Muller EG, Bloom K, Odde DJ, Davis TN.

Curr Biol. 2006 Aug 8;16(15):1489-501.


Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae.

Montpetit B, Thorne K, Barrett I, Andrews K, Jadusingh R, Hieter P, Measday V.

Genetics. 2005 Oct;171(2):489-501. Epub 2005 Jul 5.


Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor-mediated metaphase arrest.

Tunquist BJ, Eyers PA, Chen LG, Lewellyn AL, Maller JL.

J Cell Biol. 2003 Dec 22;163(6):1231-42.


Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p.

Shang C, Hazbun TR, Cheeseman IM, Aranda J, Fields S, Drubin DG, Barnes G.

Mol Biol Cell. 2003 Aug;14(8):3342-55. Epub 2003 May 3.


The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly.

Buvelot S, Tatsutani SY, Vermaak D, Biggins S.

J Cell Biol. 2003 Feb 3;160(3):329-39.


The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.

McCleland ML, Gardner RD, Kallio MJ, Daum JR, Gorbsky GJ, Burke DJ, Stukenberg PT.

Genes Dev. 2003 Jan 1;17(1):101-14.


Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication.

Stucke VM, Silljé HH, Arnaud L, Nigg EA.

EMBO J. 2002 Apr 2;21(7):1723-32.

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