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Items: 1 to 20 of 832


HIF-1α pathway: role, regulation and intervention for cancer therapy.

Masoud GN, Li W.

Acta Pharm Sin B. 2015 Sep;5(5):378-389. Epub 2015 Jun 6. Review.


Genome-wide mapping of Hif-1α binding sites in zebrafish.

Greenald D, Jeyakani J, Pelster B, Sealy I, Mathavan S, van Eeden FJ.

BMC Genomics. 2015 Nov 11;16(1):923. doi: 10.1186/s12864-015-2169-x.


Diverse of Erythropoiesis Responding to Hypoxia and Low Environmental Temperature in Vertebrates.

Maekawa S, Kato T.

Biomed Res Int. 2015;2015:747052. doi: 10.1155/2015/747052. Epub 2015 Oct 18. Review.


IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma.

Kickingereder P, Sahm F, Radbruch A, Wick W, Heiland S, Deimling Av, Bendszus M, Wiestler B.

Sci Rep. 2015 Nov 5;5:16238. doi: 10.1038/srep16238.


Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells.

Glass JJ, Phillips PA, Gunning PW, Stehn JR.

BMC Cancer. 2015 Oct 16;15:712. doi: 10.1186/s12885-015-1741-8.


Genetic and Chromosomal Aberrations and Their Clinical Significance in Renal Neoplasms.

Yap NY, Rajandram R, Ng KL, Pailoor J, Fadzli A, Gobe GC.

Biomed Res Int. 2015;2015:476508. doi: 10.1155/2015/476508. Epub 2015 Sep 13. Review.


Combined use of COX-1 and VEGF immunohistochemistry refines the histopathologic prognosis of renal cell carcinoma.

Osman WM, Youssef NS.

Int J Clin Exp Pathol. 2015 Jul 1;8(7):8165-77. eCollection 2015.


In vivo and in vitro characteristic of HIF-1α and relative genes in ischemic femoral head necrosis.

Zhang W, Yuan Z, Pei X, Ma R.

Int J Clin Exp Pathol. 2015 Jun 1;8(6):7210-6. eCollection 2015.


The Transcription Factor ZNF395 Is Required for the Maximal Hypoxic Induction of Proinflammatory Cytokines in U87-MG Cells.

Herwartz C, Castillo-Juárez P, Schröder L, Barron BL, Steger G.

Mediators Inflamm. 2015;2015:804264. doi: 10.1155/2015/804264. Epub 2015 Jul 1.


A Systems Pharmacology Model of Erythropoiesis in Mice Induced by Small Molecule Inhibitor of Prolyl Hydroxylase Enzymes.

Singh I, Nagiec EE, Thompson JM, Krzyzanski W, Singh P.

CPT Pharmacometrics Syst Pharmacol. 2015 Feb;4(2):e12. doi: 10.1002/psp4.12. Epub 2015 Feb 11.


RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.

Zhang CS, Liu Q, Li M, Lin SY, Peng Y, Wu D, Li TY, Fu Q, Jia W, Wang X, Ma T, Zong Y, Cui J, Pu C, Lian G, Guo H, Ye Z, Lin SC.

Cell Res. 2015 Sep;25(9):1025-42. doi: 10.1038/cr.2015.90. Epub 2015 Jul 28.


A large-scale prospective registration study of the safety and efficacy of sorafenib tosylate in unresectable or metastatic renal cell carcinoma in Japan: results of over 3200 consecutive cases in post-marketing all-patient surveillance.

Akaza H, Oya M, Iijima M, Hyodo I, Gemma A, Itoh H, Adachi M, Okayama Y, Sunaya T, Inuyama L.

Jpn J Clin Oncol. 2015 Oct;45(10):953-62. doi: 10.1093/jjco/hyv099. Epub 2015 Jul 22.


Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain.

Chan MC, Atasoylu O, Hodson E, Tumber A, Leung IK, Chowdhury R, Gómez-Pérez V, Demetriades M, Rydzik AM, Holt-Martyn J, Tian YM, Bishop T, Claridge TD, Kawamura A, Pugh CW, Ratcliffe PJ, Schofield CJ.

PLoS One. 2015 Jul 6;10(7):e0132004. doi: 10.1371/journal.pone.0132004. eCollection 2015.


Hypoxia-Inducible Factor-1 in Physiological and Pathophysiological Angiogenesis: Applications and Therapies.

Zimna A, Kurpisz M.

Biomed Res Int. 2015;2015:549412. doi: 10.1155/2015/549412. Epub 2015 Jun 4. Review.


Pivotal role of vascular endothelial growth factor pathway in tumor angiogenesis.

Lee SH, Jeong D, Han YS, Baek MJ.

Ann Surg Treat Res. 2015 Jul;89(1):1-8. doi: 10.4174/astr.2015.89.1.1. Epub 2015 Jun 11. Review.


Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma.

LaGory EL, Wu C, Taniguchi CM, Ding CK, Chi JT, von Eyben R, Scott DA, Richardson AD, Giaccia AJ.

Cell Rep. 2015 Jul 7;12(1):116-27. doi: 10.1016/j.celrep.2015.06.006. Epub 2015 Jun 25. Erratum in: Cell Rep. 2015 Jul 28;12(4):717.


Chenodeoxycholic Acid Reduces Hypoxia Inducible Factor-1α Protein and Its Target Genes.

Moon Y, Choi SM, Chang S, Park B, Lee S, Lee MO, Choi HS, Park H.

PLoS One. 2015 Jun 22;10(6):e0130911. doi: 10.1371/journal.pone.0130911. eCollection 2015.


Trophoblast expression of the minor histocompatibility antigen HA-1 is regulated by oxygen and is increased in placentas from preeclamptic women.

Linscheid C, Heitmann E, Singh P, Wickstrom E, Qiu L, Hodes H, Nauser T, Petroff MG.

Placenta. 2015 Aug;36(8):832-8. doi: 10.1016/j.placenta.2015.05.018. Epub 2015 Jun 6.


Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages.

Sotoodehnejadnematalahi F, Staples KJ, Chrysanthou E, Pearson H, Ziegler-Heitbrock L, Burke B.

PLoS One. 2015 Jun 9;10(6):e0125799. doi: 10.1371/journal.pone.0125799. eCollection 2015.

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