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Results: 1 to 20 of 163

1.

STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity.

Heimdal K, Sanchez-Guixé M, Aukrust I, Bollerslev J, Bruland O, Jablonski GE, Erichsen AK, Gude E, Koht JA, Erdal S, Fiskerstrand T, Haukanes BI, Boman H, Bjørkhaug L, Tallaksen CM, Knappskog PM, Johansson S.

Orphanet J Rare Dis. 2014 Sep 26;9:146. doi: 10.1186/s13023-014-0146-0.

PMID:
25258038
[PubMed - in process]
Free PMC Article
2.

Chaperoning proteins for destruction: diverse roles of Hsp70 chaperones and their co-chaperones in targeting misfolded proteins to the proteasome.

Shiber A, Ravid T.

Biomolecules. 2014 Jul 17;4(3):704-24. doi: 10.3390/biom4030704.

PMID:
25036888
[PubMed - in process]
Free PMC Article
3.

Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6.

Rodrigo-Brenni MC, Gutierrez E, Hegde RS.

Mol Cell. 2014 Jul 17;55(2):227-37. doi: 10.1016/j.molcel.2014.05.025. Epub 2014 Jun 26.

PMID:
24981174
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The E3 ligase CHIP: insights into its structure and regulation.

Paul I, Ghosh MK.

Biomed Res Int. 2014;2014:918183. doi: 10.1155/2014/918183. Epub 2014 Apr 24. Review.

PMID:
24868554
[PubMed - in process]
Free PMC Article
5.

Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system.

Timsit YE, Negishi M.

PLoS One. 2014 May 2;9(5):e96092. doi: 10.1371/journal.pone.0096092. eCollection 2014.

PMID:
24789201
[PubMed - in process]
Free PMC Article
6.

E3 ubiquitin ligase CHIP and NBR1-mediated selective autophagy protect additively against proteotoxicity in plant stress responses.

Zhou J, Zhang Y, Qi J, Chi Y, Fan B, Yu JQ, Chen Z.

PLoS Genet. 2014 Jan 30;10(1):e1004116. doi: 10.1371/journal.pgen.1004116. eCollection 2014 Jan.

PMID:
24497840
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Targeting heat shock proteins to modulate α-synuclein toxicity.

Jones DR, Moussaud S, McLean P.

Ther Adv Neurol Disord. 2014 Jan;7(1):33-51. doi: 10.1177/1756285613493469. Review.

PMID:
24409201
[PubMed]
Free PMC Article
8.

Identification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxia.

Shi Y, Wang J, Li JD, Ren H, Guan W, He M, Yan W, Zhou Y, Hu Z, Zhang J, Xiao J, Su Z, Dai M, Wang J, Jiang H, Guo J, Zhou Y, Zhang F, Li N, Du J, Xu Q, Hu Y, Pan Q, Shen L, Wang G, Xia K, Zhang Z, Tang B.

PLoS One. 2013 Dec 2;8(12):e81884. doi: 10.1371/journal.pone.0081884. eCollection 2013.

PMID:
24312598
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Molecular cochaperones: tumor growth and cancer treatment.

Calderwood SK.

Scientifica (Cairo). 2013;2013:217513. doi: 10.1155/2013/217513. Epub 2013 Apr 17. Review.

PMID:
24278769
[PubMed]
Free PMC Article
10.

Organizing principles of mammalian nonsense-mediated mRNA decay.

Popp MW, Maquat LE.

Annu Rev Genet. 2013;47:139-65. doi: 10.1146/annurev-genet-111212-133424. Review.

PMID:
24274751
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Endoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligase.

Matsumura Y, Sakai J, Skach WR.

J Biol Chem. 2013 Oct 25;288(43):31069-79. doi: 10.1074/jbc.M113.479345. Epub 2013 Aug 29.

PMID:
23990462
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.

Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B.

Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006.

PMID:
23973223
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex.

Smith MC, Scaglione KM, Assimon VA, Patury S, Thompson AD, Dickey CA, Southworth DR, Paulson HL, Gestwicki JE, Zuiderweg ER.

Biochemistry. 2013 Aug 13;52(32):5354-64. doi: 10.1021/bi4009209. Epub 2013 Aug 2.

PMID:
23865999
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

CHIP protects against cardiac pressure overload through regulation of AMPK.

Schisler JC, Rubel CE, Zhang C, Lockyer P, Cyr DM, Patterson C.

J Clin Invest. 2013 Aug 1;123(8):3588-99. doi: 10.1172/JCI69080. Epub 2013 Jul 25.

PMID:
23863712
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug.

Kao SH, Wang WL, Chen CY, Chang YL, Wu YY, Wang YT, Wang SP, Nesvizhskii AI, Chen YJ, Hong TM, Yang PC.

Oncogene. 2014 Jun 12;33(24):3172-82. doi: 10.1038/onc.2013.279. Epub 2013 Jul 15.

PMID:
23851495
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

CHIP has a protective role against oxidative stress-induced cell death through specific regulation of endonuclease G.

Lee JS, Seo TW, Yi JH, Shin KS, Yoo SJ.

Cell Death Dis. 2013 Jun 13;4:e666. doi: 10.1038/cddis.2013.181.

PMID:
23764847
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Proteomic profiling in Drosophila reveals potential Dube3a regulation of the actin cytoskeleton and neuronal homeostasis.

Jensen L, Farook MF, Reiter LT.

PLoS One. 2013 Apr 23;8(4):e61952. doi: 10.1371/journal.pone.0061952. Print 2013.

PMID:
23626758
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response.

Radovanac K, Morgner J, Schulz JN, Blumbach K, Patterson C, Geiger T, Mann M, Krieg T, Eckes B, Fässler R, Wickström SA.

EMBO J. 2013 May 15;32(10):1409-24. doi: 10.1038/emboj.2013.90. Epub 2013 Apr 23.

PMID:
23612611
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Human cytomegalovirus inhibits apoptosis by proteasome-mediated degradation of Bax at endoplasmic reticulum-mitochondrion contacts.

Zhang A, Hildreth RL, Colberg-Poley AM.

J Virol. 2013 May;87(10):5657-68. doi: 10.1128/JVI.00145-13. Epub 2013 Mar 13.

PMID:
23487455
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Hsp70 and Hsp90 multichaperone complexes sequentially regulate thiazide-sensitive cotransporter endoplasmic reticulum-associated degradation and biogenesis.

Donnelly BF, Needham PG, Snyder AC, Roy A, Khadem S, Brodsky JL, Subramanya AR.

J Biol Chem. 2013 May 3;288(18):13124-35. doi: 10.1074/jbc.M113.455394. Epub 2013 Mar 12.

PMID:
23482560
[PubMed - indexed for MEDLINE]
Free PMC Article
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