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Items: 1 to 20 of 24


Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.

Bulatov E, Ciulli A.

Biochem J. 2015 May 1;467(3):365-86. doi: 10.1042/BJ20141450. Review.


The anaphase promoting complex contributes to the degradation of the S. cerevisiae telomerase recruitment subunit Est1p.

Ferguson JL, Chao WC, Lee E, Friedman KL.

PLoS One. 2013;8(1):e55055. doi: 10.1371/journal.pone.0055055. Epub 2013 Jan 25.


Inhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapy.

Tanaka T, Nakatani T, Kamitani T.

Mol Oncol. 2012 Jun;6(3):267-75. doi: 10.1016/j.molonc.2012.01.003. Epub 2012 Jan 21. Review.


Experimental validation of Ankrd17 and Anapc10, two novel meiotic genes predicted by computational models in mice.

Ray D, Hogarth CA, Evans EB, An W, Griswold MD, Ye P.

Biol Reprod. 2012 Apr 5;86(4):102. doi: 10.1095/biolreprod.111.095216. Print 2012 Apr.


Structural insights into anaphase-promoting complex function and mechanism.

Barford D.

Philos Trans R Soc Lond B Biol Sci. 2011 Dec 27;366(1584):3605-24. doi: 10.1098/rstb.2011.0069. Review.


Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.

Buschhorn BA, Petzold G, Galova M, Dube P, Kraft C, Herzog F, Stark H, Peters JM.

Nat Struct Mol Biol. 2011 Jan;18(1):6-13. doi: 10.1038/nsmb.1979. Epub 2010 Dec 26.


A yeast's eye view of mammalian reproduction: cross-species gene co-expression in meiotic prophase.

Li Y, Lam KS, Dasgupta N, Ye P.

BMC Syst Biol. 2010 Sep 6;4:125. doi: 10.1186/1752-0509-4-125.


Animal HECT ubiquitin ligases: evolution and functional implications.

Marín I.

BMC Evol Biol. 2010 Feb 22;10:56. doi: 10.1186/1471-2148-10-56.


An excess of rare genetic variation in ABCE1 among Yorubans and African-American individuals with HIV-1.

Crawford DC, Zheng N, Speelmon EC, Stanaway I, Rieder MJ, Nickerson DA, McElrath MJ, Lingappa J.

Genes Immun. 2009 Dec;10(8):715-21. doi: 10.1038/gene.2009.57. Epub 2009 Aug 6.


The cullin7 E3 ubiquitin ligase: a novel player in growth control.

Sarikas A, Xu X, Field LJ, Pan ZQ.

Cell Cycle. 2008 Oct;7(20):3154-61. Epub 2008 Oct 4. Review.


The anaphase-promoting complex/cyclosome is required for anaphase progression in multinucleated Ashbya gossypii cells.

Gladfelter AS, Sustreanu N, Hungerbuehler AK, Voegeli S, Galati V, Philippsen P.

Eukaryot Cell. 2007 Feb;6(2):182-97. Epub 2006 Dec 8.


Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.

Skaar JR, Arai T, DeCaprio JA.

Mol Cell Biol. 2005 Jul;25(13):5579-89.


Oligosyndactylism mice have an inversion of chromosome 8.

Wise TL, Pravtcheva DD.

Genetics. 2004 Dec;168(4):2099-112.


PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate.

Pierre SC, Häusler J, Birod K, Geisslinger G, Scholich K.

EMBO J. 2004 Aug 4;23(15):3031-40. Epub 2004 Jul 15.


Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1.

Nourry C, Maksumova L, Pang M, Liu X, Wang T.

BMC Cell Biol. 2004 May 16;5:20.


Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.

Ali SH, Kasper JS, Arai T, DeCaprio JA.

J Virol. 2004 Mar;78(6):2749-57.


Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis.

Arai T, Kasper JS, Skaar JR, Ali SH, Takahashi C, DeCaprio JA.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9855-60. Epub 2003 Aug 6.


Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

Passmore LA, McCormack EA, Au SW, Paul A, Willison KR, Harper JW, Barford D.

EMBO J. 2003 Feb 17;22(4):786-96.


APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.

Tang Z, Li B, Bharadwaj R, Zhu H, Ozkan E, Hakala K, Deisenhofer J, Yu H.

Mol Biol Cell. 2001 Dec;12(12):3839-51.


Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.

Schwab M, Neutzner M, Möcker D, Seufert W.

EMBO J. 2001 Sep 17;20(18):5165-75.

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