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Results: 1 to 20 of 73

Cited In for PubMed (Select 10226025)

1.

A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.

Rettenmaier TJ, Sadowsky JD, Thomsen ND, Chen SC, Doak AK, Arkin MR, Wells JA.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18590-5. doi: 10.1073/pnas.1415365112. Epub 2014 Dec 17.

2.

Mdm20 stimulates polyQ aggregation via inhibiting autophagy through Akt-Ser473 phosphorylation.

Yasuda K, Ohyama K, Onga K, Kakizuka A, Mori N.

PLoS One. 2013 Dec 16;8(12):e82523. doi: 10.1371/journal.pone.0082523. eCollection 2013.

3.

Atypical protein kinase Cι as a human oncogene and therapeutic target.

Parker PJ, Justilien V, Riou P, Linch M, Fields AP.

Biochem Pharmacol. 2014 Mar 1;88(1):1-11. doi: 10.1016/j.bcp.2013.10.023. Epub 2013 Nov 11. Review.

4.

Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells.

James RG, Bosch KA, Kulikauskas RM, Yang PT, Robin NC, Toroni RA, Biechele TL, Berndt JD, von Haller PD, Eng JK, Wolf-Yadlin A, Chien AJ, Moon RT.

J Biol Chem. 2013 Nov 29;288(48):34658-70. doi: 10.1074/jbc.M113.500314. Epub 2013 Oct 10.

5.

PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells.

Bulloj A, Duan W, Finnemann SC.

Exp Eye Res. 2013 Aug;113:9-18. doi: 10.1016/j.exer.2013.05.002. Epub 2013 May 10.

6.

Combined RNAi-mediated suppression of Rictor and EGFR resulted in complete tumor regression in an orthotopic glioblastoma tumor model.

Verreault M, Weppler SA, Stegeman A, Warburton C, Strutt D, Masin D, Bally MB.

PLoS One. 2013;8(3):e59597. doi: 10.1371/journal.pone.0059597. Epub 2013 Mar 15.

7.

Targeting the PI3K/Akt/mTOR pathway for breast cancer therapy.

Cidado J, Park BH.

J Mammary Gland Biol Neoplasia. 2012 Dec;17(3-4):205-16. doi: 10.1007/s10911-012-9264-2. Epub 2012 Aug 4. Review.

8.

Proline dehydrogenase is essential for proline protection against hydrogen peroxide-induced cell death.

Natarajan SK, Zhu W, Liang X, Zhang L, Demers AJ, Zimmerman MC, Simpson MA, Becker DF.

Free Radic Biol Med. 2012 Sep 1;53(5):1181-91. doi: 10.1016/j.freeradbiomed.2012.07.002. Epub 2012 Jul 13.

9.

PDK1 protein phosphorylation at Thr354 by murine protein serine-threonine kinase 38 contributes to negative regulation of PDK1 protein activity.

Seong HA, Jung H, Manoharan R, Ha H.

J Biol Chem. 2012 Jun 15;287(25):20811-22. doi: 10.1074/jbc.M111.331827. Epub 2012 Apr 27.

10.

Akt: a double-edged sword in cell proliferation and genome stability.

Xu N, Lao Y, Zhang Y, Gillespie DA.

J Oncol. 2012;2012:951724. doi: 10.1155/2012/951724. Epub 2012 Mar 15.

11.

Mammalian TOR signaling to the AGC kinases.

Su B, Jacinto E.

Crit Rev Biochem Mol Biol. 2011 Dec;46(6):527-47. doi: 10.3109/10409238.2011.618113. Epub 2011 Oct 10. Review.

12.

Protein kinases and phosphatases in the control of cell fate.

Bononi A, Agnoletto C, De Marchi E, Marchi S, Patergnani S, Bonora M, Giorgi C, Missiroli S, Poletti F, Rimessi A, Pinton P.

Enzyme Res. 2011;2011:329098. doi: 10.4061/2011/329098. Epub 2011 Sep 4.

13.

Phosphorylation of AKT: a mutational analysis.

Hart JR, Vogt PK.

Oncotarget. 2011 Jun;2(6):467-76.

14.

In the newborn hippocampus, neurotrophin-dependent survival requires spontaneous activity and integrin signaling.

Murase S, Owens DF, McKay RD.

J Neurosci. 2011 May 25;31(21):7791-800. doi: 10.1523/JNEUROSCI.0202-11.2011.

15.

mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected].

Moore SF, Hunter RW, Hers I.

J Biol Chem. 2011 Jul 15;286(28):24553-60. doi: 10.1074/jbc.M110.202341. Epub 2011 May 18. Erratum in: J Biol Chem. 2011 Sep 2;286(35):31062.

16.

Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1).

Keshwani MM, von Daake S, Newton AC, Harris TK, Taylor SS.

J Biol Chem. 2011 Jul 1;286(26):23552-8. doi: 10.1074/jbc.M111.258004. Epub 2011 May 11.

17.

Multiple implications of 3-phosphoinositide-dependent protein kinase 1 in human cancer.

Li Y, Yang KJ, Park J.

World J Biol Chem. 2010 Aug 26;1(8):239-47. doi: 10.4331/wjbc.v1.i8.239.

18.

The complexes of mammalian target of rapamycin.

Zhou H, Huang S.

Curr Protein Pept Sci. 2010 Sep;11(6):409-24. Review.

19.

Discovery of PDK1 kinase inhibitors with a novel mechanism of action by ultrahigh throughput screening.

Bobkova EV, Weber MJ, Xu Z, Zhang YL, Jung J, Blume-Jensen P, Northrup A, Kunapuli P, Andersen JN, Kariv I.

J Biol Chem. 2010 Jun 11;285(24):18838-46. doi: 10.1074/jbc.M109.089946. Epub 2010 Apr 12.

20.
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