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Items: 1 to 20 of 130

1.

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition.

Castel P, Ellis H, Bago R, Toska E, Razavi P, Carmona FJ, Kannan S, Verma CS, Dickler M, Chandarlapaty S, Brogi E, Alessi DR, Baselga J, Scaltriti M.

Cancer Cell. 2016 Aug 8;30(2):229-42. doi: 10.1016/j.ccell.2016.06.004. Epub 2016 Jul 21.

2.

Role of SGK1 for fatty acid uptake, cell survival and radioresistance of NCI-H460 lung cancer cells exposed to acute or chronic cycling severe hypoxia.

Matschke J, Wiebeck E, Hurst S, Rudner J, Jendrossek V.

Radiat Oncol. 2016 Jun 1;11:75. doi: 10.1186/s13014-016-0647-1.

3.

Dexamethasone and insulin activate serum and glucocorticoid-inducible kinase 1 (SGK1) via different molecular mechanisms in cortical collecting duct cells.

Mansley MK, Watt GB, Francis SL, Walker DJ, Land SC, Bailey MA, Wilson SM.

Physiol Rep. 2016 May;4(10). pii: e12792. doi: 10.14814/phy2.12792.

4.

NDRG2 phosphorylation provides negative feedback for SGK1-dependent regulation of a kainate receptor in astrocytes.

Matschke V, Theiss C, Hollmann M, Schulze-Bahr E, Lang F, Seebohm G, Strutz-Seebohm N.

Front Cell Neurosci. 2015 Oct 6;9:387. doi: 10.3389/fncel.2015.00387. eCollection 2015.

5.
6.

Phosphoinositide dependent protein kinase 1 is required for exercise-induced cardiac hypertrophy but not the associated mitochondrial adaptations.

Noh J, Wende AR, Olsen CD, Kim B, Bevins J, Zhu Y, Zhang QJ, Riehle C, Abel ED.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):297-305. doi: 10.1016/j.yjmcc.2015.10.015. Epub 2015 Oct 22.

PMID:
26476238
7.

Phosphatidylinositolphosphate phosphatase activities and cancer.

Rudge SA, Wakelam MJ.

J Lipid Res. 2016 Feb;57(2):176-92. doi: 10.1194/jlr.R059154. Epub 2015 Aug 24.

PMID:
26302980
8.

SGK3 (CISK) may induce tumor angiogenesis (Hypothesis).

Hou M, Lai Y, He S, He W, Shen H, Ke Z.

Oncol Lett. 2015 Jul;10(1):23-26. Epub 2015 May 6.

9.

Inhibition of serum- and glucocorticoid-inducible kinase 1 enhances TLR-mediated inflammation and promotes endotoxin-driven organ failure.

Zhou H, Gao S, Duan X, Liang S, Scott DA, Lamont RJ, Wang H.

FASEB J. 2015 Sep;29(9):3737-49. doi: 10.1096/fj.15-270462. Epub 2015 May 20.

PMID:
25993992
10.

Akt isoforms in vascular disease.

Yu H, Littlewood T, Bennett M.

Vascul Pharmacol. 2015 Aug;71:57-64. doi: 10.1016/j.vph.2015.03.003. Epub 2015 Apr 28. Review.

11.

The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression.

González-Fernández R, Ávila J, Arteaga MF, Canessa CM, Martín-Vasallo P.

Int J Mol Sci. 2015 Apr 2;16(4):7462-77. doi: 10.3390/ijms16047462.

12.

Disturbance of oligodendrocyte function plays a key role in the pathogenesis of schizophrenia and major depressive disorder.

Miyata S, Hattori T, Shimizu S, Ito A, Tohyama M.

Biomed Res Int. 2015;2015:492367. doi: 10.1155/2015/492367. Epub 2015 Feb 1. Review.

13.

Control of cardiac repolarization by phosphoinositide 3-kinase signaling to ion channels.

Ballou LM, Lin RZ, Cohen IS.

Circ Res. 2015 Jan 2;116(1):127-37. doi: 10.1161/CIRCRESAHA.116.303975. Review.

14.

SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer.

Gasser JA, Inuzuka H, Lau AW, Wei W, Beroukhim R, Toker A.

Mol Cell. 2014 Nov 20;56(4):595-607. doi: 10.1016/j.molcel.2014.09.023. Epub 2014 Oct 30.

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16.

Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans.

Gatsi R, Schulze B, Rodríguez-Palero MJ, Hernando-Rodríguez B, Baumeister R, Artal-Sanz M.

PLoS One. 2014 Sep 29;9(9):e107671. doi: 10.1371/journal.pone.0107671. eCollection 2014.

17.

Serum and glucocorticoid-regulated kinase 1 promotes vascular smooth muscle cell proliferation via regulation of β-catenin dynamics.

Zhong W, Oguljahan B, Xiao Y, Nelson J, Hernandez L, Garcia-Barrio M, Francis SC.

Cell Signal. 2014 Dec;26(12):2765-72. doi: 10.1016/j.cellsig.2014.08.002. Epub 2014 Aug 22.

18.

Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area.

Heller EA, Kaska S, Fallon B, Ferguson D, Kennedy PJ, Neve RL, Nestler EJ, Mazei-Robison MS.

J Neurochem. 2015 Jan;132(2):243-53. doi: 10.1111/jnc.12925. Epub 2014 Aug 26.

19.

The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase.

Mori S, Nada S, Kimura H, Tajima S, Takahashi Y, Kitamura A, Oneyama C, Okada M.

PLoS One. 2014 Feb 18;9(2):e88891. doi: 10.1371/journal.pone.0088891. eCollection 2014.

20.

Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution.

Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, Whyte MK, Renshaw SA.

J Immunol. 2014 Feb 15;192(4):1796-805. doi: 10.4049/jimmunol.1300087. Epub 2014 Jan 15.

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