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Results: 1 to 20 of 33

1.

A new aurora in anaplastic thyroid cancer therapy.

Baldini E, D'Armiento M, Ulisse S.

Int J Endocrinol. 2014;2014:816430. doi: 10.1155/2014/816430. Epub 2014 Jul 1. Review.

PMID:
25097550
[PubMed]
Free PMC Article
2.

Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes.

Balboula AZ, Schindler K.

PLoS Genet. 2014 Feb 27;10(2):e1004194. doi: 10.1371/journal.pgen.1004194. eCollection 2014 Feb.

PMID:
24586209
[PubMed - in process]
Free PMC Article
3.

Mitotic catastrophe and cell death induced by depletion of centrosomal proteins.

Kimura M, Yoshioka T, Saio M, Banno Y, Nagaoka H, Okano Y.

Cell Death Dis. 2013 Apr 18;4:e603. doi: 10.1038/cddis.2013.108.

PMID:
23598415
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle.

Hochegger H, Hégarat N, Pereira-Leal JB.

Open Biol. 2013 Mar 20;3(3):120185. doi: 10.1098/rsob.120185. Review.

PMID:
23516109
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The pan-Aurora kinase inhibitor, PHA-739358, induces apoptosis and inhibits migration in melanoma cell lines.

Xie L, Meyskens FL Jr.

Melanoma Res. 2013 Apr;23(2):102-13. doi: 10.1097/CMR.0b013e32835df5e4.

PMID:
23344158
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Optimization of imidazo[4,5-b]pyridine-based kinase inhibitors: identification of a dual FLT3/Aurora kinase inhibitor as an orally bioavailable preclinical development candidate for the treatment of acute myeloid leukemia.

Bavetsias V, Crumpler S, Sun C, Avery S, Atrash B, Faisal A, Moore AS, Kosmopoulou M, Brown N, Sheldrake PW, Bush K, Henley A, Box G, Valenti M, de Haven Brandon A, Raynaud FI, Workman P, Eccles SA, Bayliss R, Linardopoulos S, Blagg J.

J Med Chem. 2012 Oct 25;55(20):8721-34. doi: 10.1021/jm300952s. Epub 2012 Oct 8.

PMID:
23043539
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Aurora kinase A drives MTOC biogenesis but does not trigger resumption of meiosis in mouse oocytes matured in vivo.

Solc P, Baran V, Mayer A, Bohmova T, Panenkova-Havlova G, Saskova A, Schultz RM, Motlik J.

Biol Reprod. 2012 Oct 11;87(4):85. doi: 10.1095/biolreprod.112.101014. Print 2012 Oct.

PMID:
22837479
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex.

Iyer J, Tsai MY.

Cell Signal. 2012 Aug;24(8):1677-89. doi: 10.1016/j.cellsig.2012.04.014. Epub 2012 Apr 25.

PMID:
22560880
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Aurora kinase-C-T191D is constitutively active mutant.

Khan J, Khan S, Attaullah S, Ali I, Khan SN.

BMC Cell Biol. 2012 Mar 26;13:8. doi: 10.1186/1471-2121-13-8. Retraction in: BMC Cell Biol. 2012;13:17.

PMID:
22443468
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Overexpression of active Aurora-C kinase results in cell transformation and tumour formation.

Khan J, Ezan F, Crémet JY, Fautrel A, Gilot D, Lambert M, Benaud C, Troadec MB, Prigent C.

PLoS One. 2011;6(10):e26512. doi: 10.1371/journal.pone.0026512. Epub 2011 Oct 27.

PMID:
22046298
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Aurora kinases are expressed in medullary thyroid carcinoma (MTC) and their inhibition suppresses in vitro growth and tumorigenicity of the MTC derived cell line TT.

Baldini E, Arlot-Bonnemains Y, Sorrenti S, Mian C, Pelizzo MR, De Antoni E, Palermo S, Morrone S, Barollo S, Nesca A, Moretti CG, D'Armiento M, Ulisse S.

BMC Cancer. 2011 Sep 26;11:411. doi: 10.1186/1471-2407-11-411.

PMID:
21943074
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

CCAAT/enhancer-binding protein delta mediates tumor necrosis factor alpha-induced Aurora kinase C transcription and promotes genomic instability.

Wu SR, Li CF, Hung LY, Huang AM, Tseng JT, Tsou JH, Wang JM.

J Biol Chem. 2011 Aug 19;286(33):28662-70. doi: 10.1074/jbc.M111.270710. Epub 2011 Jun 28.

PMID:
21715338
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer.

Azzariti A, Bocci G, Porcelli L, Fioravanti A, Sini P, Simone GM, Quatrale AE, Chiarappa P, Mangia A, Sebastian S, Del Bufalo D, Del Tacca M, Paradiso A.

Br J Cancer. 2011 Mar 1;104(5):769-80. doi: 10.1038/bjc.2011.21. Epub 2011 Feb 8.

PMID:
21304529
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imaging.

Moroz MA, Kochetkov T, Cai S, Wu J, Shamis M, Nair J, de Stanchina E, Serganova I, Schwartz GK, Banerjee D, Bertino JR, Blasberg RG.

Clin Cancer Res. 2011 Mar 1;17(5):1099-110. doi: 10.1158/1078-0432.CCR-10-1430. Epub 2011 Jan 18.

PMID:
21245090
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes.

Sharif B, Na J, Lykke-Hartmann K, McLaughlin SH, Laue E, Glover DM, Zernicka-Goetz M.

J Cell Sci. 2010 Dec 15;123(Pt 24):4292-300. doi: 10.1242/jcs.067447.

PMID:
21123620
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Aurora kinase inhibitors--rising stars in cancer therapeutics?

Dar AA, Goff LW, Majid S, Berlin J, El-Rifai W.

Mol Cancer Ther. 2010 Feb;9(2):268-78. doi: 10.1158/1535-7163.MCT-09-0765. Epub 2010 Feb 2. Review.

PMID:
20124450
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins.

Carmena M, Ruchaud S, Earnshaw WC.

Curr Opin Cell Biol. 2009 Dec;21(6):796-805. doi: 10.1016/j.ceb.2009.09.008. Review.

PMID:
19836940
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2.

Bibby RA, Tang C, Faisal A, Drosopoulos K, Lubbe S, Houlston R, Bayliss R, Linardopoulos S.

J Biol Chem. 2009 Nov 27;284(48):33177-84. doi: 10.1074/jbc.M109.032722. Epub 2009 Oct 2.

PMID:
19801554
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Aurora kinase B modulates chromosome alignment in mouse oocytes.

Shuda K, Schindler K, Ma J, Schultz RM, Donovan PJ.

Mol Reprod Dev. 2009 Nov;76(11):1094-105. doi: 10.1002/mrd.21075.

PMID:
19565641
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression.

Hung LY, Tseng JT, Lee YC, Xia W, Wang YN, Wu ML, Chuang YH, Lai CH, Chang WC.

Nucleic Acids Res. 2008 Aug;36(13):4337-51. doi: 10.1093/nar/gkn417. Epub 2008 Jun 27.

PMID:
18586824
[PubMed - indexed for MEDLINE]
Free PMC Article

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