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Items: 1 to 20 of 73


XB130: A novel adaptor protein in cancer signal transduction.

Zhang R, Zhang J, Wu Q, Meng F, Liu C.

Biomed Rep. 2016 Mar;4(3):300-306. Epub 2016 Feb 1.


Expression of GADS enhances FLT3-induced mitogenic signaling.

Chougule RA, Cordero E, Moharram SA, Pietras K, Rönnstrand L, Kazi JU.

Oncotarget. 2016 Mar 22;7(12):14112-24. doi: 10.18632/oncotarget.7415.


GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells.

Bilal MY, Zhang EY, Dinkel B, Hardy D, Yankee TM, Houtman JC.

Cell Signal. 2015 Apr;27(4):841-50. doi: 10.1016/j.cellsig.2015.01.012. Epub 2015 Jan 28.


Phosphorylation site dynamics of early T-cell receptor signaling.

Chylek LA, Akimov V, Dengjel J, Rigbolt KT, Hu B, Hlavacek WS, Blagoev B.

PLoS One. 2014 Aug 22;9(8):e104240. doi: 10.1371/journal.pone.0104240. eCollection 2014.


The combined loss of Gads and CD127 reveals a novel function of Gads prior to TCRβ expression.

Xiong J, Parker BL, Yankee TM.

Immunol Res. 2014 Oct;60(1):77-84. doi: 10.1007/s12026-014-8556-6.


Induction and stability of the anergic phenotype in T cells.

Valdor R, Macian F.

Semin Immunol. 2013 Nov 15;25(4):313-20. doi: 10.1016/j.smim.2013.10.010. Epub 2013 Nov 5. Review.


T cell Receptor Signal Transduction in T lymphocytes.

Gorentla BK, Zhong XP.

J Clin Cell Immunol. 2012 Oct 27;2012(Suppl 12):5.


Proteomic analysis of the SH2 domain-containing leukocyte protein of 76 kDa (SLP76) interactome in resting and activated primary mast cells [corrected].

Bounab Y, Hesse AM, Iannascoli B, Grieco L, Couté Y, Niarakis A, Roncagalli R, Lie E, Lam KP, Demangel C, Thieffry D, Garin J, Malissen B, Daëron M.

Mol Cell Proteomics. 2013 Oct;12(10):2874-89. doi: 10.1074/mcp.M112.025908. Epub 2013 Jul 2. Erratum in: Mol Cell Proteomics. 2013 Feb ;13(2):678.


Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia.

Gillis LC, Berry DM, Minden MD, McGlade CJ, Barber DL.

Leukemia. 2013 Aug;27(8):1666-76. doi: 10.1038/leu.2013.40. Epub 2013 Feb 12.


The adaptor protein LAT serves as an integration node for signaling pathways that drive T cell activation.

Bartelt RR, Houtman JC.

Wiley Interdiscip Rev Syst Biol Med. 2013 Jan-Feb;5(1):101-10. doi: 10.1002/wsbm.1194. Epub 2012 Nov 13. Review.


The importance of the Erk pathway in the development of linker for activation of T cells-mediated autoimmunity.

Fuller DM, Zhu M, Koonpaew S, Nelson MI, Zhang W.

J Immunol. 2012 Oct 15;189(8):4005-13. doi: 10.4049/jimmunol.1201380. Epub 2012 Sep 14.


SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.

Liu BA, Engelmann BW, Jablonowski K, Higginbotham K, Stergachis AB, Nash PD.

Cell Commun Signal. 2012 Sep 14;10(1):27. doi: 10.1186/1478-811X-10-27.


Actin engine in immunological synapse.

Piragyte I, Jun CD.

Immune Netw. 2012 Jun;12(3):71-83. doi: 10.4110/in.2012.12.3.71. Epub 2012 Jun 30.


SLP-76 is required for optimal CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow.

Lee D, Kim J, Baker RG, Koretzky GA, Hammer DA.

Eur J Immunol. 2012 Oct;42(10):2736-43. doi: 10.1002/eji.201142303. Epub 2012 Sep 10.


Mast cell chemotaxis - chemoattractants and signaling pathways.

Halova I, Draberova L, Draber P.

Front Immunol. 2012 May 25;3:119. doi: 10.3389/fimmu.2012.00119. eCollection 2012.


Transmembrane adaptor proteins in the high-affinity IgE receptor signaling.

Draber P, Halova I, Levi-Schaffer F, Draberova L.

Front Immunol. 2012 Jan 11;2:95. doi: 10.3389/fimmu.2011.00095. eCollection 2011.


Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.

de Castro RO, Zhang J, Groves JR, Barbu EA, Siraganian RP.

J Biol Chem. 2012 Mar 9;287(11):8194-204. doi: 10.1074/jbc.M111.326850. Epub 2012 Jan 20.


Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation.

Lasserre R, Cuche C, Blecher-Gonen R, Libman E, Biquand E, Danckaert A, Yablonski D, Alcover A, Di Bartolo V.

J Cell Biol. 2011 Nov 28;195(5):839-53. doi: 10.1083/jcb.201103105. Epub 2011 Nov 21.


The SLP-76 Src homology 2 domain is required for T cell development and activation.

Burns JC, Corbo E, Degen J, Gohil M, Anterasian C, Schraven B, Koretzky GA, Kliche S, Jordan MS.

J Immunol. 2011 Nov 1;187(9):4459-66. doi: 10.4049/jimmunol.0903379. Epub 2011 Sep 26.


Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells.

Sela M, Bogin Y, Beach D, Oellerich T, Lehne J, Smith-Garvin JE, Okumura M, Starosvetsky E, Kosoff R, Libman E, Koretzky G, Kambayashi T, Urlaub H, Wienands J, Chernoff J, Yablonski D.

EMBO J. 2011 Jul 1;30(15):3160-72. doi: 10.1038/emboj.2011.213.

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