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Results: 1 to 20 of 130

1.

Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis.

Tarrant TK, Silver PB, Wahlsten JL, Rizzo LV, Chan CC, Wiggert B, Caspi RR.

J Exp Med. 1999 Jan 18;189(2):219-30.

PMID:
9892605
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response.

Jones LS, Rizzo LV, Agarwal RK, Tarrant TK, Chan CC, Wiggert B, Caspi RR.

J Immunol. 1997 Jun 15;158(12):5997-6005.

PMID:
9190954
[PubMed - indexed for MEDLINE]
3.

Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis.

Tarrant TK, Silver PB, Chan CC, Wiggert B, Caspi RR.

J Immunol. 1998 Jul 1;161(1):122-7.

PMID:
9647215
[PubMed - indexed for MEDLINE]
Free Article
4.

Protective effect of the type IV phosphodiesterase inhibitor rolipram in EAU: protection is independent of IL-10-inducing activity.

Xu H, Strassmann G, Chan CC, Rizzo LV, Silver PB, Wiggert B, Caspi RR.

Invest Ophthalmol Vis Sci. 1999 Apr;40(5):942-50.

PMID:
10102291
[PubMed - indexed for MEDLINE]
Free Article
5.

SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU).

Vistica BP, Shi G, Nugent L, Tan C, Altman A, Gery I.

Mol Vis. 2012;18:1858-64. Epub 2012 Jul 7.

PMID:
22815639
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Differentiation of Th1 and Th2 cells in lymph nodes and spleens of mice during experimental autoimmune uveoretinitis.

Takeuchi M, Yokoi H, Tsukahara R, Sakai J, Usui M.

Jpn J Ophthalmol. 2001 Sep-Oct;45(5):463-9.

PMID:
11583666
[PubMed - indexed for MEDLINE]
7.
8.
9.

Exogenous nitric oxide inhibits experimental autoimmune uveoretinitis development in Lewis rats by modulation of the Th1-dependent immune response.

Kwak HJ, Yang YS, Pae HO, Kim YM, Chung HT.

Mol Cells. 2001 Oct 31;12(2):178-84.

PMID:
11710518
[PubMed - indexed for MEDLINE]
Free Article
10.

Delayed onset and decreased severity of experimental autoimmune uveoretinitis in mice lacking nitric oxide synthase type 2.

Thillaye-Goldenberg B, Goureau O, Naud MC, de Kozak Y.

J Neuroimmunol. 2000 Oct 2;110(1-2):31-44.

PMID:
11024532
[PubMed - indexed for MEDLINE]
11.

Abrogation of anti-retinal autoimmunity in IL-10 transgenic mice due to reduced T cell priming and inhibition of disease effector mechanisms.

Agarwal RK, Horai R, Viley AM, Silver PB, Grajewski RS, Su SB, Yazdani AT, Zhu W, Kronenberg M, Murray PJ, Rutschman RL, Chan CC, Caspi RR.

J Immunol. 2008 Apr 15;180(8):5423-9.

PMID:
18390724
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Activation of invariant NKT cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses.

Grajewski RS, Hansen AM, Agarwal RK, Kronenberg M, Sidobre S, Su SB, Silver PB, Tsuji M, Franck RW, Lawton AP, Chan CC, Caspi RR.

J Immunol. 2008 Oct 1;181(7):4791-7.

PMID:
18802082
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis.

Haruta H, Ohguro N, Fujimoto M, Hohki S, Terabe F, Serada S, Nomura S, Nishida K, Kishimoto T, Naka T.

Invest Ophthalmol Vis Sci. 2011 May 17;52(6):3264-71. doi: 10.1167/iovs.10-6272.

PMID:
21330657
[PubMed - indexed for MEDLINE]
Free Article
14.

Mice deficient in inducible nitric oxide synthase are susceptible to experimental autoimmune uveoretinitis.

Silver PB, Tarrant TK, Chan CC, Wiggert B, Caspi RR.

Invest Ophthalmol Vis Sci. 1999 May;40(6):1280-4.

PMID:
10235566
[PubMed - indexed for MEDLINE]
Free Article
15.

The role of TLR2, TRL3, TRL4, and TRL9 signaling in the pathogenesis of autoimmune disease in a retinal autoimmunity model.

Fang J, Fang D, Silver PB, Wen F, Li B, Ren X, Lin Q, Caspi RR, Su SB.

Invest Ophthalmol Vis Sci. 2010 Jun;51(6):3092-9. doi: 10.1167/iovs.09-4754. Epub 2010 Jan 27.

PMID:
20107166
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

S-nitrosoglutathione prevents interphotoreceptor retinoid-binding protein (IRBP(161-180))-induced experimental autoimmune uveitis.

Haq E, Rohrer B, Nath N, Crosson CE, Singh I.

J Ocul Pharmacol Ther. 2007 Jun;23(3):221-31.

PMID:
17593005
[PubMed - indexed for MEDLINE]
17.

Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis.

Keino H, Watanabe T, Sato Y, Niikura M, Wada Y, Okada AA.

Arthritis Res Ther. 2008;10(5):R122. doi: 10.1186/ar2530. Epub 2008 Oct 13.

PMID:
18847496
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

CCR5-deficient mice develop experimental autoimmune uveoretinitis in the context of a deviant effector response.

Takeuchi A, Usui Y, Takeuchi M, Hattori T, Kezuka T, Suzuki J, Okunuki Y, Iwasaki T, Haino M, Matsushima K, Usui M.

Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3753-60.

PMID:
16186359
[PubMed - indexed for MEDLINE]
Free Article
19.

Endogenous systemic IFN-gamma has a protective role against ocular autoimmunity in mice.

Caspi RR, Chan CC, Grubbs BG, Silver PB, Wiggert B, Parsa CF, Bahmanyar S, Billiau A, Heremans H.

J Immunol. 1994 Jan 15;152(2):890-9.

PMID:
8283058
[PubMed - indexed for MEDLINE]
20.

Methimazole protects from experimental autoimmune uveitis (EAU) by inhibiting antigen presenting cell function and reducing antigen priming.

Wang P, Sun SH, Silver PB, Chan CC, Agarwal RK, Wiggert B, Kohn LD, Jamieson GA Jr, Caspi RR.

J Leukoc Biol. 2003 Jan;73(1):57-64.

PMID:
12525562
[PubMed - indexed for MEDLINE]
Free Article

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