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Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development.

van der Flier A, Badu-Nkansah K, Whittaker CA, Crowley D, Bronson RT, Lacy-Hulbert A, Hynes RO.

Development. 2010 Jul;137(14):2439-49. doi: 10.1242/dev.049551.


Synergistic activities of alpha3 and alpha6 integrins are required during apical ectodermal ridge formation and organogenesis in the mouse.

De Arcangelis A, Mark M, Kreidberg J, Sorokin L, Georges-Labouesse E.

Development. 1999 Sep;126(17):3957-68.


Role for the alpha7beta1 integrin in vascular development and integrity.

Flintoff-Dye NL, Welser J, Rooney J, Scowen P, Tamowski S, Hatton W, Burkin DJ.

Dev Dyn. 2005 Sep;234(1):11-21.


Consequences of lack of beta 1 integrin gene expression in mice.

Fässler R, Meyer M.

Genes Dev. 1995 Aug 1;9(15):1896-908.


The role of alphav integrins during angiogenesis.

Eliceiri BP, Cheresh DA.

Mol Med. 1998 Dec;4(12):741-50. Review. No abstract available.


Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death.

McCarty JH, Lacy-Hulbert A, Charest A, Bronson RT, Crowley D, Housman D, Savill J, Roes J, Hynes RO.

Development. 2005 Jan;132(1):165-76. Epub 2004 Dec 2.


In vivo roles of integrins during leukocyte development and traffic: insights from the analysis of mice chimeric for alpha 5, alpha v, and alpha 4 integrins.

Arroyo AG, Taverna D, Whittaker CA, Strauch UG, Bader BL, Rayburn H, Crowley D, Parker CM, Hynes RO.

J Immunol. 2000 Oct 15;165(8):4667-75.


Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins.

Reynolds LE, Wyder L, Lively JC, Taverna D, Robinson SD, Huang X, Sheppard D, Hynes RO, Hodivala-Dilke KM.

Nat Med. 2002 Jan;8(1):27-34.


Overlapping and independent functions of fibronectin receptor integrins in early mesodermal development.

Yang JT, Bader BL, Kreidberg JA, Ullman-Culleré M, Trevithick JE, Hynes RO.

Dev Biol. 1999 Nov 15;215(2):264-77.


Functional consequences of integrin gene mutations in mice.

Bouvard D, Brakebusch C, Gustafsson E, Aszódi A, Bengtsson T, Berna A, Fässler R.

Circ Res. 2001 Aug 3;89(3):211-23. Review.


Loss of p53 compensates for alpha v-integrin function in retinal neovascularization.

Strömblad S, Fotedar A, Brickner H, Theesfeld C, Aguilar de Diaz E, Friedlander M, Cheresh DA.

J Biol Chem. 2002 Apr 19;277(16):13371-4. Epub 2002 Feb 20.


βPix plays a dual role in cerebral vascular stability and angiogenesis, and interacts with integrin αvβ8.

Liu J, Zeng L, Kennedy RM, Gruenig NM, Childs SJ.

Dev Biol. 2012 Mar 1;363(1):95-105. doi: 10.1016/j.ydbio.2011.12.022. Epub 2011 Dec 22.


Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins.

McCarty JH, Monahan-Earley RA, Brown LF, Keller M, Gerhardt H, Rubin K, Shani M, Dvorak HF, Wolburg H, Bader BL, Dvorak AM, Hynes RO.

Mol Cell Biol. 2002 Nov;22(21):7667-77.


The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

Eliceiri BP, Cheresh DA.

J Clin Invest. 1999 May;103(9):1227-30. Review. No abstract available.


Role of alpha v integrins during angiogenesis.

Eliceiri BP, Cheresh DA.

Cancer J. 2000 May;6 Suppl 3:S245-9. Review.


Functional overlap and cooperativity among alphav and beta1 integrin subfamilies during skin angiogenesis.

Perruzzi CA, de Fougerolles AR, Koteliansky VE, Whelan MC, Westlin WF, Senger DR.

J Invest Dermatol. 2003 Jun;120(6):1100-9.


Beta1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis.

Tanjore H, Zeisberg EM, Gerami-Naini B, Kalluri R.

Dev Dyn. 2008 Jan;237(1):75-82.

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