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Items: 1 to 20 of 171

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Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing.

Sekine N, Cirulli V, Regazzi R, Brown LJ, Gine E, Tamarit-Rodriguez J, Girotti M, Marie S, MacDonald MJ, Wollheim CB, et al.

J Biol Chem. 1994 Feb 18;269(7):4895-902.

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Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets.

Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Kikuchi M, Yazaki Y, Miyazaki JI, Oka Y.

Diabetologia. 1993 Nov;36(11):1139-45.

PMID:
8270128
7.

Overexpression of hexokinase I but not GLUT1 glucose transporter alters concentration dependence of glucose-stimulated insulin secretion in pancreatic beta-cell line MIN6.

Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Kikuchi M, Yazaki Y, Miyazaki J, Oka Y.

J Biol Chem. 1994 Jan 28;269(4):3081-7.

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Insulin secretion and differential gene expression in glucose-responsive and -unresponsive MIN6 sublines.

Minami K, Yano H, Miki T, Nagashima K, Wang CZ, Tanaka H, Miyazaki JI, Seino S.

Am J Physiol Endocrinol Metab. 2000 Oct;279(4):E773-81.

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Enzymic activities in two populations of purified rat islet beta-cells.

Sener A, Mercan D, Malaisse WJ.

Int J Mol Med. 2001 Sep;8(3):285-9.

PMID:
11494057
10.

Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.

Becker TC, Noel RJ, Johnson JH, Lynch RM, Hirose H, Tokuyama Y, Bell GI, Newgard CB.

J Biol Chem. 1996 Jan 5;271(1):390-4.

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Characterization of a novel glucose-responsive insulin-secreting cell line, BRIN-BD11, produced by electrofusion.

McClenaghan NH, Barnett CR, Ah-Sing E, Abdel-Wahab YH, O'Harte FP, Yoon TW, Swanston-Flatt SK, Flatt PR.

Diabetes. 1996 Aug;45(8):1132-40.

PMID:
8690162
12.

Glucose regulates glucokinase activity in cultured islets from rat pancreas.

Liang Y, Najafi H, Matschinsky FM.

J Biol Chem. 1990 Oct 5;265(28):16863-6.

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ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans.

Al-Majed HT, Jones PM, Persaud SJ, Sugden D, Huang GC, Amiel S, Whitehouse BJ.

J Endocrinol. 2004 Jan;180(1):155-66.

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Regulation of insulin secretion from novel engineered insulinoma cell lines.

Hohmeier HE, BeltrandelRio H, Clark SA, Henkel-Rieger R, Normington K, Newgard CB.

Diabetes. 1997 Jun;46(6):968-77.

PMID:
9166667
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Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas.

Tsuruzoe K, Araki E, Furukawa N, Shirotani T, Matsumoto K, Kaneko K, Motoshima H, Yoshizato K, Shirakami A, Kishikawa H, Miyazaki J, Shichiri M.

Diabetes. 1998 Apr;47(4):621-31.

PMID:
9568696
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Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells.

Ishihara H, Nakazaki M, Kanegae Y, Inukai K, Asano T, Katagiri H, Yazaki Y, Kikuchi M, Miyazaki J, Saito I, Oka Y.

Diabetes. 1996 Sep;45(9):1238-44.

PMID:
8772729
18.

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.

Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB.

Diabetes. 2000 Mar;49(3):424-30.

PMID:
10868964
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Human GLUT-2 overexpression does not affect glucose-stimulated insulin secretion in MIN6 cells.

Ishihara H, Asano T, Tsukuda K, Katagiri H, Inukai K, Anai M, Yazaki Y, Miyazaki J, Kikuchi M, Oka Y.

Am J Physiol. 1995 Nov;269(5 Pt 1):E897-902.

PMID:
7491941
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