Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 140

1.

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways.

Velier J, Kim M, Schwarz C, Kim TW, Sapp E, Chase K, Aronin N, DiFiglia M.

Exp Neurol. 1998 Jul;152(1):34-40.

PMID:
9682010
[PubMed - indexed for MEDLINE]
2.

Mutant huntingtin impairs vesicle formation from recycling endosomes by interfering with Rab11 activity.

Li X, Standley C, Sapp E, Valencia A, Qin ZH, Kegel KB, Yoder J, Comer-Tierney LA, Esteves M, Chase K, Alexander J, Masso N, Sobin L, Bellve K, Tuft R, Lifshitz L, Fogarty K, Aronin N, DiFiglia M.

Mol Cell Biol. 2009 Nov;29(22):6106-16. doi: 10.1128/MCB.00420-09. Epub 2009 Sep 14.

PMID:
19752198
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Analysis of Huntingtin-associated protein 1 in mouse brain and immortalized striatal neurons.

Martin EJ, Kim M, Velier J, Sapp E, Lee HS, Laforet G, Won L, Chase K, Bhide PG, Heller A, Aronin N, Difiglia M.

J Comp Neurol. 1999 Jan 25;403(4):421-30.

PMID:
9888310
[PubMed - indexed for MEDLINE]
4.

Forskolin and dopamine D1 receptor activation increase huntingtin's association with endosomes in immortalized neuronal cells of striatal origin.

Kim M, Velier J, Chase K, Laforet G, Kalchman MA, Hayden MR, Won L, Heller A, Aronin N, Difiglia M.

Neuroscience. 1999;89(4):1159-67.

PMID:
10362304
[PubMed - indexed for MEDLINE]
5.

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription.

Kegel KB, Meloni AR, Yi Y, Kim YJ, Doyle E, Cuiffo BG, Sapp E, Wang Y, Qin ZH, Chen JD, Nevins JR, Aronin N, DiFiglia M.

J Biol Chem. 2002 Mar 1;277(9):7466-76. Epub 2001 Dec 5.

PMID:
11739372
[PubMed - indexed for MEDLINE]
Free Article
6.

Abnormal association of mutant huntingtin with synaptic vesicles inhibits glutamate release.

Li H, Wyman T, Yu ZX, Li SH, Li XJ.

Hum Mol Genet. 2003 Aug 15;12(16):2021-30.

PMID:
12913073
[PubMed - indexed for MEDLINE]
Free Article
7.

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

Kegel KB, Kim M, Sapp E, McIntyre C, Castaño JG, Aronin N, DiFiglia M.

J Neurosci. 2000 Oct 1;20(19):7268-78.

PMID:
11007884
[PubMed - indexed for MEDLINE]
Free Article
8.

Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.

Kim M, Lee HS, LaForet G, McIntyre C, Martin EJ, Chang P, Kim TW, Williams M, Reddy PH, Tagle D, Boyce FM, Won L, Heller A, Aronin N, DiFiglia M.

J Neurosci. 1999 Feb 1;19(3):964-73.

PMID:
9920660
[PubMed - indexed for MEDLINE]
Free Article
9.

Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease.

Valencia A, Reeves PB, Sapp E, Li X, Alexander J, Kegel KB, Chase K, Aronin N, DiFiglia M.

J Neurosci Res. 2010 Jan;88(1):179-90. doi: 10.1002/jnr.22184.

PMID:
19642201
[PubMed - indexed for MEDLINE]
10.

Wild-type huntingtin participates in protein trafficking between the Golgi and the extracellular space.

Strehlow AN, Li JZ, Myers RM.

Hum Mol Genet. 2007 Feb 15;16(4):391-409. Epub 2006 Dec 22.

PMID:
17189290
[PubMed - indexed for MEDLINE]
Free Article
11.

Interaction of huntingtin fragments with brain membranes--clues to early dysfunction in Huntington's disease.

Suopanki J, Götz C, Lutsch G, Schiller J, Harjes P, Herrmann A, Wanker EE.

J Neurochem. 2006 Feb;96(3):870-84. Epub 2006 Jan 9.

PMID:
16405500
[PubMed - indexed for MEDLINE]
12.

Polyglutamine expansion in huntingtin alters its interaction with phospholipids.

Kegel KB, Sapp E, Alexander J, Valencia A, Reeves P, Li X, Masso N, Sobin L, Aronin N, DiFiglia M.

J Neurochem. 2009 Sep;110(5):1585-97. doi: 10.1111/j.1471-4159.2009.06255.x. Epub 2009 Jun 29.

PMID:
19566678
[PubMed - indexed for MEDLINE]
13.

Expression of normal and mutant huntingtin in the developing brain.

Bhide PG, Day M, Sapp E, Schwarz C, Sheth A, Kim J, Young AB, Penney J, Golden J, Aronin N, DiFiglia M.

J Neurosci. 1996 Sep 1;16(17):5523-35.

PMID:
8757264
[PubMed - indexed for MEDLINE]
Free Article
14.

The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human.

Gutekunst CA, Li SH, Yi H, Ferrante RJ, Li XJ, Hersch SM.

J Neurosci. 1998 Oct 1;18(19):7674-86.

PMID:
9742138
[PubMed - indexed for MEDLINE]
Free Article
15.

Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling.

Maycox PR, Link E, Reetz A, Morris SA, Jahn R.

J Cell Biol. 1992 Sep;118(6):1379-88.

PMID:
1325974
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Expression of mutant N-terminal huntingtin fragment (htt552-100Q) in astrocytes suppresses the secretion of BDNF.

Wang L, Lin F, Wang J, Wu J, Han R, Zhu L, Difiglia M, Qin Z.

Brain Res. 2012 Apr 17;1449:69-82. doi: 10.1016/j.brainres.2012.01.077. Epub 2012 Feb 23.

PMID:
22410294
[PubMed - indexed for MEDLINE]
17.

Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus.

del Toro D, Alberch J, Lázaro-Diéguez F, Martín-Ibáñez R, Xifró X, Egea G, Canals JM.

Mol Biol Cell. 2009 Mar;20(5):1478-92. doi: 10.1091/mbc.E08-07-0726. Epub 2009 Jan 14.

PMID:
19144827
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo.

Trushina E, Singh RD, Dyer RB, Cao S, Shah VH, Parton RG, Pagano RE, McMurray CT.

Hum Mol Genet. 2006 Dec 15;15(24):3578-91.

PMID:
17142251
[PubMed - indexed for MEDLINE]
Free Article
19.

Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins.

Huang CC, Faber PW, Persichetti F, Mittal V, Vonsattel JP, MacDonald ME, Gusella JF.

Somat Cell Mol Genet. 1998 Jul;24(4):217-33.

PMID:
10410676
[PubMed - indexed for MEDLINE]
20.

Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells.

Chun W, Lesort M, Tucholski J, Faber PW, MacDonald ME, Ross CA, Johnson GV.

Neurobiol Dis. 2001 Jun;8(3):391-404.

PMID:
11442349
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk