Similar articles for PMID: 9680315

Year	Number of Results
1991	1
1993	1
1995	1
1996	5
1997	14
1998	17
1999	21
2000	14
2001	5
2002	7
2003	3
2004	4
2005	1
2006	5
2007	1
2008	1
2009	1
2010	2
2015	1
2017	1
2018	3
2019	1
2020	2
2021	2
2022	3
2024	0

1

Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing.

Baumeister R, Leimer U, Zweckbronner I, Jakubek C, Grünberg J, Haass C. Baumeister R, et al. Genes Funct. 1997 Apr;1(2):149-59. doi: 10.1046/j.1365-4624.1997.00012.x. Genes Funct. 1997. PMID: 9680315

2

HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling.

Li X, Greenwald I. Li X, et al. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12204-9. doi: 10.1073/pnas.94.22.12204. Proc Natl Acad Sci U S A. 1997. PMID: 9342387 Free PMC article.

3

Presenilin is required for proper morphology and function of neurons in C. elegans.

Wittenburg N, Eimer S, Lakowski B, Röhrig S, Rudolph C, Baumeister R. Wittenburg N, et al. Nature. 2000 Jul 20;406(6793):306-9. doi: 10.1038/35018575. Nature. 2000. PMID: 10917532

4

A loss of function mutant of the presenilin homologue SEL-12 undergoes aberrant endoproteolysis in Caenorhabditis elegans and increases abeta 42 generation in human cells.

Okochi M, Eimer S, Bottcher A, Baumeister R, Romig H, Walter J, Capell A, Steiner H, Haass C. Okochi M, et al. J Biol Chem. 2000 Dec 29;275(52):40925-32. doi: 10.1074/jbc.M005254200. J Biol Chem. 2000. PMID: 11013240 Free article.

5

Suppressors of the egg-laying defective phenotype of sel-12 presenilin mutants implicate the CoREST corepressor complex in LIN-12/Notch signaling in C. elegans.

Jarriault S, Greenwald I. Jarriault S, et al. Genes Dev. 2002 Oct 15;16(20):2713-28. doi: 10.1101/gad.1022402. Genes Dev. 2002. PMID: 12381669 Free PMC article.

6

Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans.

Zhang DM, Levitan D, Yu G, Nishimura M, Chen F, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Liang Y, Holmes E, Milman P, Sato C, Zhang L, St George-Hyslop P. Zhang DM, et al. Neuroreport. 2000 Sep 28;11(14):3227-30. doi: 10.1097/00001756-200009280-00035. Neuroreport. 2000. PMID: 11043553

7

Notch-1 activation by familial Alzheimer's disease (FAD)-linked mutant forms of presenilin-1.

Nakajima M, Shimizu T, Shirasawa T. Nakajima M, et al. J Neurosci Res. 2000 Oct 15;62(2):311-7. doi: 10.1002/1097-4547(20001015)62:2<311::AID-JNR16>3.0.CO;2-G. J Neurosci Res. 2000. PMID: 11020224

8

Mutations in genes involved in nonsense mediated decay ameliorate the phenotype of sel-12 mutants with amber stop mutations in Caenorhabditis elegans.

Gontijo AM, Aubert S, Roelens I, Lakowski B. Gontijo AM, et al. BMC Genet. 2009 Mar 20;10:14. doi: 10.1186/1471-2156-10-14. BMC Genet. 2009. PMID: 19302704 Free PMC article.

9

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans.

Levitan D, Doyle TG, Brousseau D, Lee MK, Thinakaran G, Slunt HH, Sisodia SS, Greenwald I. Levitan D, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14940-4. doi: 10.1073/pnas.93.25.14940. Proc Natl Acad Sci U S A. 1996. PMID: 8962160 Free PMC article.

10

Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling.

Westlund B, Parry D, Clover R, Basson M, Johnson CD. Westlund B, et al. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2497-502. doi: 10.1073/pnas.96.5.2497. Proc Natl Acad Sci U S A. 1999. PMID: 10051671 Free PMC article.

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