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Results: 1 to 20 of 320

1.
2.

Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons.

Virdee K, Xue L, Hemmings BA, Goemans C, Heumann R, Tolkovsky AM.

Brain Res. 1999 Aug 7;837(1-2):127-42.

PMID:
10433995
[PubMed - indexed for MEDLINE]
3.

Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons.

Orike N, Middleton G, Borthwick E, Buchman V, Cowen T, Davies AM.

J Cell Biol. 2001 Sep 3;154(5):995-1005. Epub 2001 Aug 27.

PMID:
11524433
[PubMed - indexed for MEDLINE]
Free PMC Article
4.
5.

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway.

Mazzoni IE, Saïd FA, Aloyz R, Miller FD, Kaplan D.

J Neurosci. 1999 Nov 15;19(22):9716-27.

PMID:
10559381
[PubMed - indexed for MEDLINE]
Free Article
6.

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons.

Philpott KL, McCarthy MJ, Klippel A, Rubin LL.

J Cell Biol. 1997 Nov 3;139(3):809-15.

PMID:
9348296
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

Eilers A, Whitfield J, Babij C, Rubin LL, Ham J.

J Neurosci. 1998 Mar 1;18(5):1713-24.

PMID:
9464996
[PubMed - indexed for MEDLINE]
Free Article
8.

Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3.

Barber AJ, Nakamura M, Wolpert EB, Reiter CE, Seigel GM, Antonetti DA, Gardner TW.

J Biol Chem. 2001 Aug 31;276(35):32814-21. Epub 2001 Jul 6.

PMID:
11443130
[PubMed - indexed for MEDLINE]
Free Article
9.

Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons.

Tsui-Pierchala BA, Putcha GV, Johnson EM Jr.

J Neurosci. 2000 Oct 1;20(19):7228-37.

PMID:
11007879
[PubMed - indexed for MEDLINE]
Free Article
11.

Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival.

Vaillant AR, Mazzoni I, Tudan C, Boudreau M, Kaplan DR, Miller FD.

J Cell Biol. 1999 Sep 6;146(5):955-66.

PMID:
10477751
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line.

Eves EM, Xiong W, Bellacosa A, Kennedy SG, Tsichlis PN, Rosner MR, Hay N.

Mol Cell Biol. 1998 Apr;18(4):2143-52.

PMID:
9528786
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.

Shimamura H, Terada Y, Okado T, Tanaka H, Inoshita S, Sasaki S.

J Am Soc Nephrol. 2003 Jun;14(6):1427-34.

PMID:
12761242
[PubMed - indexed for MEDLINE]
Free Article
15.

Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway.

Bai RY, Ouyang T, Miething C, Morris SW, Peschel C, Duyster J.

Blood. 2000 Dec 15;96(13):4319-27.

PMID:
11110708
[PubMed - indexed for MEDLINE]
Free Article
16.

Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways.

Subramaniam S, Strelau J, Unsicker K.

J Biol Chem. 2003 Mar 14;278(11):8904-12. Epub 2003 Jan 3.

PMID:
12514175
[PubMed - indexed for MEDLINE]
Free Article
18.

The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth.

Ashcroft M, Stephens RM, Hallberg B, Downward J, Kaplan DR.

Oncogene. 1999 Aug 12;18(32):4586-97.

PMID:
10467403
[PubMed - indexed for MEDLINE]
Free Article
19.

S100B increases proliferation in PC12 neuronal cells and reduces their responsiveness to nerve growth factor via Akt activation.

Arcuri C, Bianchi R, Brozzi F, Donato R.

J Biol Chem. 2005 Feb 11;280(6):4402-14. Epub 2004 Nov 30.

PMID:
15572370
[PubMed - indexed for MEDLINE]
Free Article

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