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Results: 1 to 20 of 95

1.

Variable region domain exchange influences the functional properties of IgG.

Morrison SL, Porter SB, Trinh KR, Wims LA, Denham J, Oi VT.

J Immunol. 1998 Mar 15;160(6):2802-8.

PMID:
9510182
[PubMed - indexed for MEDLINE]
Free Article
2.

Influence of the isotype of the light chain on the properties of IgG.

Monta├▒o RF, Morrison SL.

J Immunol. 2002 Jan 1;168(1):224-31.

PMID:
11751966
[PubMed - indexed for MEDLINE]
Free Article
3.
4.

Variable region domain exchange in human IgGs promotes antibody complex formation with accompanying structural changes and altered effector functions.

Chan LA, Phillips ML, Wims LA, Trinh KR, Denham J, Morrison SL.

Mol Immunol. 2004 Jul;41(5):527-38.

PMID:
15183931
[PubMed - indexed for MEDLINE]
5.
6.

Human IgG1 Cgamma1 domain is crucial for the bioactivity of the engineered anti-CD20 antibodies.

Geng S, Feng J, Li Y, Kang X, Sun Y, Gu X, Huang Y, Chang H, Shen BF.

Cell Mol Immunol. 2007 Apr;4(2):121-5.

PMID:
17484806
[PubMed - indexed for MEDLINE]
Free Article
7.

The antigen binding domain of non-idiotypic human anti-F(ab')2 autoantibodies: study of their interaction with IgG hinge region epitopes.

Welschof M, Reineke U, Kleist C, Kipriyanov S, Little M, Volkmer-Engert R, Schneider-Mergener J, Opelz G, Terness P.

Hum Immunol. 1999 Apr;60(4):282-90.

PMID:
10363719
[PubMed - indexed for MEDLINE]
8.

Absolute conservation of residue 6 of immunoglobulin heavy chain variable regions of class IIA is required for correct folding.

de Haard HJ, Kazemier B, van der Bent A, Oudshoorn P, Boender P, van Gemen B, Arends JW, Hoogenboom HR.

Protein Eng. 1998 Dec;11(12):1267-76.

PMID:
9930677
[PubMed - indexed for MEDLINE]
Free Article
9.

The immunoglobulin heavy chain constant region affects kinetic and thermodynamic parameters of antibody variable region interactions with antigen.

Torres M, Fernández-Fuentes N, Fiser A, Casadevall A.

J Biol Chem. 2007 May 4;282(18):13917-27. Epub 2007 Mar 12.

PMID:
17353196
[PubMed - indexed for MEDLINE]
Free Article
10.

Isotype can affect the fine specificity of an antibody for a polysaccharide antigen.

McLean GR, Torres M, Elguezabal N, Nakouzi A, Casadevall A.

J Immunol. 2002 Aug 1;169(3):1379-86.

PMID:
12133962
[PubMed - indexed for MEDLINE]
Free Article
11.

Horse cytokine/IgG fusion proteins--mammalian expression of biologically active cytokines and a system to verify antibody specificity to equine cytokines.

Wagner B, Robeson J, McCracken M, Wattrang E, Antczak DF.

Vet Immunol Immunopathol. 2005 May 1;105(1-2):1-14.

PMID:
15797470
[PubMed - indexed for MEDLINE]
12.

Chimeric mouse human IgG3 antibodies with an IgG4-like hinge region induce complement-mediated lysis more efficiently than IgG3 with normal hinge.

Norderhaug L, Brekke OH, Bremnes B, Sandin R, Aase A, Michaelsen TE, Sandlie I.

Eur J Immunol. 1991 Oct;21(10):2379-84.

PMID:
1915551
[PubMed - indexed for MEDLINE]
14.
15.

Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.

Staelens S, Desmet J, Ngo TH, Vauterin S, Pareyn I, Barbeaux P, Van Rompaey I, Stassen JM, Deckmyn H, Vanhoorelbeke K.

Mol Immunol. 2006 Mar;43(8):1243-57. Epub 2005 Aug 22.

PMID:
16118019
[PubMed - indexed for MEDLINE]
16.

A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells.

Michaelsen TE, Thommesen JE, Ihle O, Gregers TF, Sandin RH, Brekke OH, Sandlie I.

Eur J Immunol. 2006 Jan;36(1):129-38.

PMID:
16323243
[PubMed - indexed for MEDLINE]
17.

Circular Dichroism reveals evidence of coupling between immunoglobulin constant and variable region secondary structure.

Janda A, Casadevall A.

Mol Immunol. 2010 Apr;47(7-8):1421-5. doi: 10.1016/j.molimm.2010.02.018. Epub 2010 Mar 17.

PMID:
20299100
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Enhancement of complement activation and cytolysis of human IgG3 by deletion of hinge exons.

Michaelsen TE, Aase A, Westby C, Sandlie I.

Scand J Immunol. 1990 Nov;32(5):517-28.

PMID:
2125362
[PubMed - indexed for MEDLINE]
20.

Position effects of variable region carbohydrate on the affinity and in vivo behavior of an anti-(1-->6) dextran antibody.

Coloma MJ, Trinh RK, Martinez AR, Morrison SL.

J Immunol. 1999 Feb 15;162(4):2162-70.

PMID:
9973491
[PubMed - indexed for MEDLINE]
Free Article

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