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Results: 1 to 20 of 137

1.

A DNA double-strand break defective fibroblast cell line (180BR) derived from a radiosensitive patient represents a new mutant phenotype.

Badie C, Goodhardt M, Waugh A, Doyen N, Foray N, Calsou P, Singleton B, Gell D, Salles B, Jeggo P, Arlett CF, Malaise EP.

Cancer Res. 1997 Oct 15;57(20):4600-7.

PMID:
9377575
[PubMed - indexed for MEDLINE]
Free Article
2.

Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient.

Riballo E, Critchlow SE, Teo SH, Doherty AJ, Priestley A, Broughton B, Kysela B, Beamish H, Plowman N, Arlett CF, Lehmann AR, Jackson SP, Jeggo PA.

Curr Biol. 1999 Jul 1;9(13):699-702.

PMID:
10395545
[PubMed - indexed for MEDLINE]
Free Article
3.

The radiosensitive cell line 180BR is not defective in the major DNA damage-sensing proteins.

Lu H, Song Q, Arlett C, Lavin MF.

Cancer Res. 1998 Jan 1;58(1):84-8.

PMID:
9426062
[PubMed - indexed for MEDLINE]
Free Article
4.

Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.

Wang H, Zeng ZC, Perrault AR, Cheng X, Qin W, Iliakis G.

Nucleic Acids Res. 2001 Apr 15;29(8):1653-60.

PMID:
11292837
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20.

Priestley A, Beamish HJ, Gell D, Amatucci AG, Muhlmann-Diaz MC, Singleton BK, Smith GC, Blunt T, Schalkwyk LC, Bedford JS, Jackson SP, Jeggo PA, Taccioli GE.

Nucleic Acids Res. 1998 Apr 15;26(8):1965-73.

PMID:
9518490
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

A new X-ray sensitive CHO cell mutant of ionizing radiation group 7,XR-C2, that is defective in DSB repair but has only a mild defect in V(D)J recombination.

Errami A, Overkamp WJ, He DM, Friedl AA, Gell DA, Eckardt-Schupp F, Jackson SP, Hendrickson EA, Lohman PH, Zdzienicka MZ.

Mutat Res. 2000 Sep 15;461(1):59-69.

PMID:
10980412
[PubMed - indexed for MEDLINE]
7.

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016. Epub 2009 Jul 5.

PMID:
19583974
[PubMed - indexed for MEDLINE]
8.

Restoration of T cell-specific V(D)J recombination in DNA-PKcs(-/-) mice by ionizing radiation: The effects on survival, development, and tumorigenesis.

Li XL, Shen SR, Wang S, Ouyang HH, Li GC.

Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2002 Mar;34(2):149-57.

PMID:
12006988
[PubMed - indexed for MEDLINE]
Free Article
9.

Defective repair of DNA double-strand breaks and chromosome damage in fibroblasts from a radiosensitive leukemia patient.

Badie C, Iliakis G, Foray N, Alsbeih G, Pantellias GE, Okayasu R, Cheong N, Russell NS, Begg AC, Arlett CF, et al.

Cancer Res. 1995 Mar 15;55(6):1232-4.

PMID:
7882314
[PubMed - indexed for MEDLINE]
Free Article
11.

The scid factor on human chromosome 8 restores V(D)J recombination in addition to double-strand break repair.

Komatsu K, Kubota N, Gallo M, Okumura Y, Lieber MR.

Cancer Res. 1995 Apr 15;55(8):1774-9.

PMID:
7712487
[PubMed - indexed for MEDLINE]
Free Article
12.

Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines.

Badie C, Iliakis G, Foray N, Alsbeih G, Cedervall B, Chavaudra N, Pantelias G, Arlett C, Malaise EP.

Radiat Res. 1995 Oct;144(1):26-35.

PMID:
7568768
[PubMed - indexed for MEDLINE]
13.

Transfer of Ku86 RNA antisense decreases the radioresistance of human fibroblasts.

Marangoni E, Le Romancer M, Foray N, Muller C, Douc-Rasy S, Vaganay S, Abdulkarim B, Barrois M, Calsou P, Bernier J, Salles B, Bourhis J.

Cancer Gene Ther. 2000 Feb;7(2):339-46.

PMID:
10770645
[PubMed - indexed for MEDLINE]
Free Article
14.
15.

Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells.

Collis SJ, Ketner GW, Hicks JL, Nelson WG, Demarzo AM, Deweese TL.

Int J Radiat Biol. 2003 Jan;79(1):53-60.

PMID:
12556331
[PubMed - indexed for MEDLINE]
16.

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

Riballo E, Kühne M, Rief N, Doherty A, Smith GC, Recio MJ, Reis C, Dahm K, Fricke A, Krempler A, Parker AR, Jackson SP, Gennery A, Jeggo PA, Löbrich M.

Mol Cell. 2004 Dec 3;16(5):715-24.

PMID:
15574327
[PubMed - indexed for MEDLINE]
17.

An ionizing radiation-sensitive CHO mutant cell line: irs-20. IV. Genetic complementation, V(D)J recombination and the scid phenotype.

Lin JY, Mühlmann-Diaz MC, Stackhouse MA, Robinson JF, Taccioli GE, Chen DJ, Bedford JS.

Radiat Res. 1997 Feb;147(2):166-71.

PMID:
9008208
[PubMed - indexed for MEDLINE]
18.

Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination.

Kienker LJ, Shin EK, Meek K.

Nucleic Acids Res. 2000 Jul 15;28(14):2752-61.

PMID:
10908332
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

Jeggo PA, Taccioli GE, Jackson SP.

Bioessays. 1995 Nov;17(11):949-57. Review.

PMID:
8526889
[PubMed - indexed for MEDLINE]
20.

Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle.

Lee SE, Mitchell RA, Cheng A, Hendrickson EA.

Mol Cell Biol. 1997 Mar;17(3):1425-33.

PMID:
9032269
[PubMed - indexed for MEDLINE]
Free PMC Article

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