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Results: 1 to 20 of 323

1.

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.

Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ.

Science. 1997 Sep 5;277(5331):1497-501.

PMID:
9278511
[PubMed - indexed for MEDLINE]
Free Article
2.

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216.

Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H.

Science. 1997 Sep 5;277(5331):1501-5.

PMID:
9278512
[PubMed - indexed for MEDLINE]
Free Article
3.

Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1.

Zeng Y, Forbes KC, Wu Z, Moreno S, Piwnica-Worms H, Enoch T.

Nature. 1998 Oct 1;395(6701):507-10.

PMID:
9774107
[PubMed - indexed for MEDLINE]
4.

Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase.

Furnari B, Rhind N, Russell P.

Science. 1997 Sep 5;277(5331):1495-7.

PMID:
9278510
[PubMed - indexed for MEDLINE]
Free Article
5.

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms.

Sanchez Y, Bachant J, Wang H, Hu F, Liu D, Tetzlaff M, Elledge SJ.

Science. 1999 Nov 5;286(5442):1166-71.

PMID:
10550056
[PubMed - indexed for MEDLINE]
Free Article
6.

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.

Matsuoka S, Huang M, Elledge SJ.

Science. 1998 Dec 4;282(5395):1893-7.

PMID:
9836640
[PubMed - indexed for MEDLINE]
Free Article
7.

Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1.

Furnari B, Blasina A, Boddy MN, McGowan CH, Russell P.

Mol Biol Cell. 1999 Apr;10(4):833-45.

PMID:
10198041
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Replication checkpoint enforced by kinases Cds1 and Chk1.

Boddy MN, Furnari B, Mondesert O, Russell P.

Science. 1998 May 8;280(5365):909-12.

PMID:
9572736
[PubMed - indexed for MEDLINE]
Free Article
9.

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein.

Lopez-Girona A, Furnari B, Mondesert O, Russell P.

Nature. 1999 Jan 14;397(6715):172-5.

PMID:
9923681
[PubMed - indexed for MEDLINE]
10.

Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.

Lee HJ, Hwang HI, Jang YJ.

Cell Cycle. 2010 Jun 15;9(12):2389-98. Epub 2010 Jun 15.

PMID:
20581453
[PubMed - indexed for MEDLINE]
Free Article
11.

Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding.

Hutchins JR, Dikovskaya D, Clarke PR.

FEBS Lett. 2002 Sep 25;528(1-3):267-71.

PMID:
12297318
[PubMed - indexed for MEDLINE]
12.

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase.

Blasina A, de Weyer IV, Laus MC, Luyten WH, Parker AE, McGowan CH.

Curr Biol. 1999 Jan 14;9(1):1-10.

PMID:
9889122
[PubMed - indexed for MEDLINE]
Free Article
13.

Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest.

Capasso H, Palermo C, Wan S, Rao H, John UP, O'Connell MJ, Walworth NC.

J Cell Sci. 2002 Dec 1;115(Pt 23):4555-64.

PMID:
12415000
[PubMed - indexed for MEDLINE]
Free Article
14.

A DNA damage checkpoint meets the cell cycle engine.

Weinert T.

Science. 1997 Sep 5;277(5331):1450-1. No abstract available.

PMID:
9304216
[PubMed - indexed for MEDLINE]
15.

Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II.

Hutchins JR, Dikovskaya D, Clarke PR.

Mol Biol Cell. 2003 Oct;14(10):4003-14. Epub 2003 Jul 11. Erratum in: Mol Biol Cell. 2005 Mar;16(3):1568.

PMID:
14517314
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling.

Jurvansuu J, Fragkos M, Ingemarsdotter C, Beard P.

J Mol Biol. 2007 Sep 14;372(2):397-406. Epub 2007 Jul 3.

PMID:
17663993
[PubMed - indexed for MEDLINE]
17.

The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts.

Kumagai A, Guo Z, Emami KH, Wang SX, Dunphy WG.

J Cell Biol. 1998 Sep 21;142(6):1559-69.

PMID:
9744884
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The Chk1-Cdc25C regulation is involved in sensitizing A253 cells to a novel topoisomerase I inhibitor BNP1350 by bax gene transfer.

Yin M, Hapke G, Guo B, Azrak RG, Frank C, Rustum YM.

Oncogene. 2001 Aug 30;20(38):5249-57.

PMID:
11536038
[PubMed - indexed for MEDLINE]
Free Article
19.

C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding.

Peng CY, Graves PR, Ogg S, Thoma RS, Byrnes MJ 3rd, Wu Z, Stephenson MT, Piwnica-Worms H.

Cell Growth Differ. 1998 Mar;9(3):197-208.

PMID:
9543386
[PubMed - indexed for MEDLINE]
Free Article
20.

DNA damage: Chk1 and Cdc25, more than meets the eye.

Walworth NC.

Curr Opin Genet Dev. 2001 Feb;11(1):78-82. Review.

PMID:
11163155
[PubMed - indexed for MEDLINE]
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