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9084410,9886060,8769854,8816273,9210523,10668447,10486197,8615854,11223912,14756808,12042097,7498411,9300398,9930721,11007874,10972962,10874687,11279257,11170720,16081051,8791003,14635220,7475942,9030641,7505825,7512617,12746225,8584110,11746384,11738131,11387401,11782971,8844700,19666192,8884386,20052014,9139243,15858417,16706843,9538905,7540679,15139026,10894179,10668444,9676750,11895374,7538561,9758158,12421605,10095077,10627601,11445182,8522949,9254679,15255976,15557470,9572271,10219977,10476684,1371601,7527559,12699785,9424022,8739156,10715585,10530818,18328812,10592292,28322832,9617487,15806114,10493110,20457221,7720791,2568579,10796040,1980647,16000124,8556324,8890280,1689850,9648857,11134617,15350646,9292202,9109508,10773011,8821749,9166755,9788286,14637103,15695547,9648865,12008069,8713451,7520539,9464649,9918228,7595547,7722657,19913087,11701154,9401673,7559406,9758154,11122374,12809699,10051767,10737619,9391008,12093081,7685870,11087221,7870298,8946051,10218861,14698758,7538570,11978403,10383638,8713457,11483648,8613786,11595759,9742143,7595504,7540678,11520892,10804193,9357063,16340463,11958537,9698321,9041361,8075826,10213187,10078615,7514651,7643087,15574735,7504083,10820201,10653015,9348336,8769858,11359879,7472462,7509863,9209112,9043714,7519663,7545794,9655508,34089465,9084441,9577844,12821189,14514037,19822212,7523591,8762714,7722497,9855300,11958530,7751911,23449322,9111031,10456232,9798924,10650884,7521953,11739640,19226256,10820206,19020286,33713149,7751912,9767383,12379242,26134564,7643085,12533598,18666632,9391010,7510053,11876774,10844014,18289526,12435411,1649249,12117583,8841983,8522995,11298788,9231719,12622405,9133370,9550304,8143904,7509048,19145290,21556733,11488951,15537885,12044483,8783198,14622914,8093648,15703386,12384442,7908723,8455139,12657683,12741473,32722349,9106742,9805276,7514776,11733718,11401823,12871585,11985829,1927584,10341246,11483661,7643968,7513843,7531122,10674493,10804206,7904304,12842286,9482210,7643082,8921275,1353614,1380682,9058043,7495376,10025666,7536828,9931492,12052443,10748226,19340578,12759177,14968164,12832529,7528074,14992287,18522896,12654475,12153475,7545016,11876769,14753440,15210575,9348349,8978741,11720781,10501564,18305246,23559014,10473275,1362603,10098629,8757258,16601148,9832133,9753187,9464944,16923173,14507968,9003036,10051219,19396876,7838320,7616215,7969911,10366003,9011746,33089839,24349798,7901348,12875909,7532210,35746896,12358723,10024352,17392461,10964947,9572298,23721822,30883902,7643105,9216985,34891041,8929986,9231736,9364453,8455022,12843260,10215519,9596563,8753869,12490613,11874198,11920724,7506590,12065656,31147524,7566374,31945382,11839752,10428039,18283118,10098868,11138735,12644387,9282922,11432983,10428417,8529264,12784912,19462233,1421132,9500601,33817875,22921461,10871701,17360906,7513376,19214610,31167782,7477670,10465686,7542179,8824316,9526039,9281459,8997504,11335047,7526660,2570129,11069579,15009636,9753133,9507950,7529611,20651809,9151719,8613724,30194439,11087222,1717307,9677417,21620933,17006121,12832516,8101871,12417645,9718133,16510724,10203336,10683854,14596851,11567785,12504881,10493776,12003848,8971763,16442504,20945398,10066141,36286468,7540711,11339637,14625034,11914719,10901265,32701951,9786205,10501475,17121841,11668082,22253441,9693788,12614334,11277591,12742598,1976762,9285640,9987035,9007759,12093097,11522957,29463792,11905998,18354023,11996657,18483069,11737151,12820987,19513417,12590940,9648867,7643961,18715754,7554232,12799020,10632599,7541298,10947802,9685580,9241442,7536809,12231429,19236863,11182258,7505417,1922771,17944868,12401608,10510185,8104432,8654784,15773908,8789949,10802384,9084420,12621038,32783140,24967436,10098884,7507336,9593226,11146002,7538642,15991512,11564417,10651855,10507549,1346802,8737404,9692761,15201334,7643130,21371490,15994856,7595523,8835783,19005059,1983355,10783394,7533557,18363826,7561880,8815895,14600500,9539127,10908611,14720220,7651616,18667711,1318298,7790896,1358879,1970220,19429793,7544183,11486239,3385492,33497742,12351268,10510201,11520895,7526607,1963475,18619982,9440691,11209938,1431900,3385493,9489718,7533140,10461910,19853865,1625806,12640005,1332807,20489728,10987843,11113517,9121686,12524178,25016660,7504079,16805812,1982523,14523099,24802057,1671584,19084587,12467596,16782274,19384574,10402559,14552910,1979692,12387359,9596557,18372514,11448516,9928847,1922921,9468383,12909079,23658158,8120630,12764097,1359475,7529505,25180671,31296845,10553956,11642660,9084433,12153528,11070093,22018691,22992730,7907262,9081629,2156190,9568533,7475243,9495544,14678751,23804203,9877315,11259864,1680739,21509037,9697120,21029094,31085233,16775128,3925091,12559098,23719929,21624785,8455043,11179042,10958396,8848283,30649102,9464998,24323418,30714959,12628649,19285052,2190715,12480091,15161371,11461967,8614293,14980205,20157393,18315563,12828983,8940101,9832158,31673221,11589990,9003041,22940423,21414921,11684327,10627578,9522167,11413243,30783614,11312602,9552164,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Evidence that the early loss of membrane protein kinase C is a necessary step in the excitatory amino acid-induced death of primary cortical neurons.

Durkin JP, Tremblay R, Chakravarthy B, Mealing G, Morley P, Small D, Song D. Durkin JP, et al. J Neurochem. 1997 Apr;68(4):1400-12. doi: 10.1046/j.1471-4159.1997.68041400.x. J Neurochem. 1997. PMID: 9084410 Free article.

Evidence that brain-derived neurotrophic factor neuroprotection is linked to its ability to reverse the NMDA-induced inactivation of protein kinase C in cortical neurons.

Tremblay R, Hewitt K, Lesiuk H, Mealing G, Morley P, Durkin JP. Tremblay R, et al. J Neurochem. 1999 Jan;72(1):102-11. doi: 10.1046/j.1471-4159.1999.0720102.x. J Neurochem. 1999. PMID: 9886060 Free article.

An early loss in membrane protein kinase C activity precedes the excitatory amino acid-induced death of primary cortical neurons.

Durkin JP, Tremblay R, Buchan A, Blosser J, Chakravarthy B, Mealing G, Morley P, Song D. Durkin JP, et al. J Neurochem. 1996 Mar;66(3):951-62. doi: 10.1046/j.1471-4159.1996.66030951.x. J Neurochem. 1996. PMID: 8769854

Developmental changes in glutamate receptor-activated translocation of protein kinase C in cerebellar granule neurons.

Barrios M, Liljequist S. Barrios M, et al. Brain Res Dev Brain Res. 1996 Jun 14;94(1):22-30. doi: 10.1016/0165-3806(96)00039-9. Brain Res Dev Brain Res. 1996. PMID: 8816273

Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons.

Griffiths R, Malcolm C, Ritchie L, Frandsen A, Schousboe A, Scott M, Rumsby P, Meredith C. Griffiths R, et al. J Neurosci Res. 1997 Jun 15;48(6):533-42. doi: 10.1002/(sici)1097-4547(19970615)48:6<533::aid-jnr6>3.0.co;2-b. J Neurosci Res. 1997. PMID: 9210523

Intracellular survival pathways against glutamate receptor agonist excitotoxicity in cultured neurons. Intracellular calcium responses.

Marini AM, Ueda Y, June CH. Marini AM, et al. Ann N Y Acad Sci. 1999;890:421-37. doi: 10.1111/j.1749-6632.1999.tb08021.x. Ann N Y Acad Sci. 1999. PMID: 10668447

NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.

Chen Q, Surmeier DJ, Reiner A. Chen Q, et al. Exp Neurol. 1999 Sep;159(1):283-96. doi: 10.1006/exnr.1999.7135. Exp Neurol. 1999. PMID: 10486197

Effects of decahydroisoquinoline-3-carboxylic acid monohydrate, a novel AMPA receptor antagonist, on glutamate-induced CA2+ responses and neurotoxicity in rat cortical and cerebellar granule neurons.

Liljequist S, Cebers G, Kalda A. Liljequist S, et al. Biochem Pharmacol. 1995 Nov 27;50(11):1761-74. doi: 10.1016/0006-2952(95)02032-2. Biochem Pharmacol. 1995. PMID: 8615854

N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.

Urushitani M, Nakamizo T, Inoue R, Sawada H, Kihara T, Honda K, Akaike A, Shimohama S. Urushitani M, et al. J Neurosci Res. 2001 Mar 1;63(5):377-87. doi: 10.1002/1097-4547(20010301)63:5<377::AID-JNR1032>3.0.CO;2-#. J Neurosci Res. 2001. PMID: 11223912

Hypoxia increases calcium flux through cortical neuron glutamate receptors via protein kinase C.

Bickler PE, Fahlman CS, Ferriero DM. Bickler PE, et al. J Neurochem. 2004 Feb;88(4):878-84. doi: 10.1046/j.1471-4159.2003.02203.x. J Neurochem. 2004. PMID: 14756808 Free article.

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