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Results: 1 to 20 of 85

1.

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

Wang Q, Stacy T, Binder M, Marin-Padilla M, Sharpe AH, Speck NA.

Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3444-9.

PMID:
8622955
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo.

Wang Q, Stacy T, Miller JD, Lewis AF, Gu TL, Huang X, Bushweller JH, Bories JC, Alt FW, Ryan G, Liu PP, Wynshaw-Boris A, Binder M, Marín-Padilla M, Sharpe AH, Speck NA.

Cell. 1996 Nov 15;87(4):697-708.

PMID:
8929538
[PubMed - indexed for MEDLINE]
Free Article
3.

Core-binding factor: a central player in hematopoiesis and leukemia.

Speck NA, Stacy T, Wang Q, North T, Gu TL, Miller J, Binder M, Marín-Padilla M.

Cancer Res. 1999 Apr 1;59(7 Suppl):1789s-1793s. Review.

PMID:
10197598
[PubMed - indexed for MEDLINE]
4.
5.

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR.

Cell. 1996 Jan 26;84(2):321-30.

PMID:
8565077
[PubMed - indexed for MEDLINE]
Free Article
6.

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

Yergeau DA, Hetherington CJ, Wang Q, Zhang P, Sharpe AH, Binder M, Marín-Padilla M, Tenen DG, Speck NA, Zhang DE.

Nat Genet. 1997 Mar;15(3):303-6.

PMID:
9054947
[PubMed - indexed for MEDLINE]
7.

Hematopoietic deficiencies and core binding factor expression in murine Ts16, an animal model for Down syndrome.

Gjertson C, Sturm KS, Berger CN.

Clin Immunol. 1999 Apr;91(1):50-60.

PMID:
10219254
[PubMed - indexed for MEDLINE]
8.

Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta.

Sasaki K, Yagi H, Bronson RT, Tominaga K, Matsunashi T, Deguchi K, Tani Y, Kishimoto T, Komori T.

Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12359-63.

PMID:
8901586
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor.

Niki M, Okada H, Takano H, Kuno J, Tani K, Hibino H, Asano S, Ito Y, Satake M, Noda T.

Proc Natl Acad Sci U S A. 1997 May 27;94(11):5697-702.

PMID:
9159135
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.

Lo Coco F, Pisegna S, Diverio D.

Haematologica. 1997 May-Jun;82(3):364-70. Review.

PMID:
9234595
[PubMed - indexed for MEDLINE]
Free Article
11.

AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.

Okada H, Watanabe T, Niki M, Takano H, Chiba N, Yanai N, Tani K, Hibino H, Asano S, Mucenski ML, Ito Y, Noda T, Satake M.

Oncogene. 1998 Nov 5;17(18):2287-93.

PMID:
9811459
[PubMed - indexed for MEDLINE]
Free Article
12.

Dysplastic definitive hematopoiesis in AML1/EVI1 knock-in embryos.

Maki K, Yamagata T, Asai T, Yamazaki I, Oda H, Hirai H, Mitani K.

Blood. 2005 Sep 15;106(6):2147-55. Epub 2005 May 24.

PMID:
15914564
[PubMed - indexed for MEDLINE]
Free Article
13.

Zebrafish homolog of the leukemia gene CBFB: its expression during embryogenesis and its relationship to scl and gata-1 in hematopoiesis.

Blake T, Adya N, Kim CH, Oates AC, Zon L, Chitnis A, Weinstein BM, Liu PP.

Blood. 2000 Dec 15;96(13):4178-84.

PMID:
11110689
[PubMed - indexed for MEDLINE]
Free Article
14.

Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.

Kalev-Zylinska ML, Horsfield JA, Flores MV, Postlethwait JH, Vitas MR, Baas AM, Crosier PS, Crosier KE.

Development. 2002 Apr;129(8):2015-30.

PMID:
11934867
[PubMed - indexed for MEDLINE]
Free Article
15.

CBFA2(AML1) translocations with novel partner chromosomes in myeloid leukemias: association with prior therapy.

Roulston D, Espinosa R 3rd, Nucifora G, Larson RA, Le Beau MM, Rowley JD.

Blood. 1998 Oct 15;92(8):2879-85.

PMID:
9763573
[PubMed - indexed for MEDLINE]
Free Article
16.

Cbfa2 is required for the formation of intra-aortic hematopoietic clusters.

North T, Gu TL, Stacy T, Wang Q, Howard L, Binder M, Marín-Padilla M, Speck NA.

Development. 1999 Jun;126(11):2563-75.

PMID:
10226014
[PubMed - indexed for MEDLINE]
Free Article
17.

The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.

Zent CS, Mathieu C, Claxton DF, Zhang DE, Tenen DG, Rowley JD, Nucifora G.

Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1044-8.

PMID:
8577711
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Overexpression of AML1 renders a T hybridoma resistant to T cell receptor-mediated apoptosis.

Fujii M, Hayashi K, Niki M, Chiba N, Meguro K, Endo K, Kameoka J, Ito S, Abe K, Watanabe T, Satake M.

Oncogene. 1998 Oct 8;17(14):1813-20.

PMID:
9778047
[PubMed - indexed for MEDLINE]
Free Article
19.

Familial mutations of the transcription factor RUNX1 (AML1, CBFA2) predispose to acute myeloid leukemia.

Ganly P, Walker LC, Morris CM.

Leuk Lymphoma. 2004 Jan;45(1):1-10. Review.

PMID:
15061191
[PubMed - indexed for MEDLINE]
20.

Biological characteristics of the leukemia-associated transcriptional factor AML1 disclosed by hematopoietic rescue of AML1-deficient embryonic stem cells by using a knock-in strategy.

Okuda T, Takeda K, Fujita Y, Nishimura M, Yagyu S, Yoshida M, Akira S, Downing JR, Abe T.

Mol Cell Biol. 2000 Jan;20(1):319-28.

PMID:
10594034
[PubMed - indexed for MEDLINE]
Free PMC Article

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