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Items: 1 to 20 of 150

1.
2.

Disposition of drugs in cystic fibrosis. V. In vivo CYP2C9 activity as probed by (S)-warfarin is not enhanced in cystic fibrosis.

O'Sullivan TA, Wang JP, Unadkat JD, al-Habet SM, Trager WF, Smith AL, McNamara S, Aitken ML.

Clin Pharmacol Ther. 1993 Sep;54(3):323-8.

PMID:
8375128
3.

Selective inhibition of warfarin metabolism by diltiazem in humans.

Abernethy DR, Kaminsky LS, Dickinson TH.

J Pharmacol Exp Ther. 1991 Apr;257(1):411-5.

PMID:
2020000
4.

Determination of unbound warfarin enantiomers in human plasma and 7-hydroxywarfarin in human urine by chiral stationary-phase liquid chromatography with ultraviolet or fluorescence and on-line circular dichroism detection.

Takahashi H, Kashima T, Kimura S, Muramoto N, Nakahata H, Kubo S, Shimoyama Y, Kajiwara M, Echizen H.

J Chromatogr B Biomed Sci Appl. 1997 Nov 7;701(1):71-80.

PMID:
9389340
5.

Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes.

Takahashi H, Kashima T, Nomizo Y, Muramoto N, Shimizu T, Nasu K, Kubota T, Kimura S, Echizen H.

Clin Pharmacol Ther. 1998 May;63(5):519-28.

PMID:
9630825
6.

Disposition of warfarin enantiomers and metabolites in patients during multiple dosing with rac-warfarin.

Chan E, McLachlan AJ, Pegg M, MacKay AD, Cole RB, Rowland M.

Br J Clin Pharmacol. 1994 Jun;37(6):563-9.

7.

Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin.

Kaminsky LS, Dunbar DA, Wang PP, Beaune P, Larrey D, Guengerich FP, Schnellmann RG, Sipes IG.

Drug Metab Dispos. 1984 Jul-Aug;12(4):470-7.

PMID:
6148215
8.

Human P450 metabolism of warfarin.

Kaminsky LS, Zhang ZY.

Pharmacol Ther. 1997;73(1):67-74. Review.

PMID:
9014207
9.

Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies.

Kunze KL, Wienkers LC, Thummel KE, Trager WF.

Drug Metab Dispos. 1996 Apr;24(4):414-21.

PMID:
8801056
10.

The role of cytochrome P450 3A4 in alfentanil clearance. Implications for interindividual variability in disposition and perioperative drug interactions.

Kharasch ED, Russell M, Mautz D, Thummel KE, Kunze KL, Bowdle A, Cox K.

Anesthesiology. 1997 Jul;87(1):36-50.

PMID:
9232132
11.

Disposition of drugs in cystic fibrosis. III. Acetaminophen.

Hutabarat RM, Unadkat JD, Kushmerick P, Aitken ML, Slattery JT, Smith AL.

Clin Pharmacol Ther. 1991 Dec;50(6):695-701.

PMID:
1752114
12.

Disposition of drugs in cystic fibrosis. I. Sulfamethoxazole and trimethoprim.

Hutabarat RM, Unadkat JD, Sahajwalla C, McNamara S, Ramsey B, Smith AL.

Clin Pharmacol Ther. 1991 Apr;49(4):402-9.

PMID:
2015729
13.

The mechanism of the warfarin-rifampin drug interaction in humans.

Heimark LD, Gibaldi M, Trager WF, O'Reilly RA, Goulart DA.

Clin Pharmacol Ther. 1987 Oct;42(4):388-94.

PMID:
3665337
14.

Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients.

Takahashi H, Wilkinson GR, Caraco Y, Muszkat M, Kim RB, Kashima T, Kimura S, Echizen H.

Clin Pharmacol Ther. 2003 Mar;73(3):253-63.

PMID:
12621390
15.

Kinetic study of cytochrome P450 3A4 activity on warfarin by capillary electrophoresis with fluorescence detection.

Zhang J, Ha PT, Lou Y, Hoogmartens Ja, Van Schepdael A.

J Chromatogr A. 2005 Aug 5;1082(2):235-9.

PMID:
16035367
16.

The mechanism of the interaction between amiodarone and warfarin in humans.

Heimark LD, Wienkers L, Kunze K, Gibaldi M, Eddy AC, Trager WF, O'Reilly RA, Goulart DA.

Clin Pharmacol Ther. 1992 Apr;51(4):398-407.

PMID:
1563209
18.

In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.

Ngui JS, Chen Q, Shou M, Wang RW, Stearns RA, Baillie TA, Tang W.

Drug Metab Dispos. 2001 Jun;29(6):877-86.

19.

Simultaneous determination of warfarin and 7-hydroxywarfarin enantiomers by high-performance liquid chromatography with ultraviolet detection.

Miura M, Okuyama S, Kato S, Kagaya H, Murata A, Komatsuda A, Wakui H, Sawada K.

Ther Drug Monit. 2011 Feb;33(1):108-14. doi: 10.1097/FTD.0b013e31820176d6.

PMID:
21157402
20.

Phase II metabolism of warfarin in primary culture of adult rat hepatocytes.

Jansing RL, Chao ES, Kaminsky LS.

Mol Pharmacol. 1992 Jan;41(1):209-15.

PMID:
1732719
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