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An alternatively spliced form of the transcription factor Sp1 containing only a single glutamine-rich transactivation domain.

Persengiev SP, Saffer JD, Kilpatrick DL.

Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9107-11.


Synergistic activation by the glutamine-rich domains of human transcription factor Sp1.

Courey AJ, Holtzman DA, Jackson SP, Tjian R.

Cell. 1989 Dec 1;59(5):827-36.


Molecular cloning and analysis of two subunits of the human TFIID complex: hTAFII130 and hTAFII100.

Tanese N, Saluja D, Vassallo MF, Chen JL, Admon A.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13611-6.


The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain.

Lee YH, Williams SC, Baer M, Sterneck E, Gonzalez FJ, Johnson PF.

Mol Cell Biol. 1997 Apr;17(4):2038-47.


An inhibitor domain in Sp3 regulates its glutamine-rich activation domains.

Dennig J, Beato M, Suske G.

EMBO J. 1996 Oct 15;15(20):5659-67.


The SANT domain of human MI-ER1 interacts with Sp1 to interfere with GC box recognition and repress transcription from its own promoter.

Ding Z, Gillespie LL, Mercer FC, Paterno GD.

J Biol Chem. 2004 Jul 2;279(27):28009-16. Epub 2004 Apr 26.


Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.

Koutsodontis G, Tentes I, Papakosta P, Moustakas A, Kardassis D.

J Biol Chem. 2001 Aug 3;276(31):29116-25. Epub 2001 May 30.


Synergistic regulation of human cystathionine-beta-synthase-1b promoter by transcription factors NF-YA isoforms and Sp1.

Ge Y, Jensen TL, Matherly LH, Taub JW.

Biochim Biophys Acta. 2002 Dec 12;1579(2-3):73-80.


Direct physical interactions between HNF-4 and Sp1 mediate synergistic transactivation of the apolipoprotein CIII promoter.

Kardassis D, Falvey E, Tsantili P, Hadzopoulou-Cladaras M, Zannis V.

Biochemistry. 2002 Jan 29;41(4):1217-28.


Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells.

Chen C, Zhou Y, Zhou Z, Sun X, Otto KB, Uht RM, Dong JT.

Gene. 2004 Apr 14;330:133-42.


Conservation of glutamine-rich transactivation function between yeast and humans.

Escher D, Bodmer-Glavas M, Barberis A, Schaffner W.

Mol Cell Biol. 2000 Apr;20(8):2774-82.


Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK.

Lee JA, Suh DC, Kang JE, Kim MH, Park H, Lee MN, Kim JM, Jeon BN, Roh HE, Yu MY, Choi KY, Kim KY, Hur MW.

J Biol Chem. 2005 Jul 29;280(30):28061-71. Epub 2005 May 6.


Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3.

Hagen G, Dennig J, Preiss A, Beato M, Suske G.

J Biol Chem. 1995 Oct 20;270(42):24989-94.

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