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Items: 1 to 20 of 373

1.

Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

Fiering S, Epner E, Robinson K, Zhuang Y, Telling A, Hu M, Martin DI, Enver T, Ley TJ, Groudine M.

Genes Dev. 1995 Sep 15;9(18):2203-13.

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Analysis of the developmental and transcriptional potentiation functions of 5'HS2 of the murine beta-globin locus control region in transgenic mice.

Enver T, Li Q, Gale KB, Hu M, May GE, Karlinsey JE, Jimenez G, Papayannopoulou T, Costantini F.

Dev Biol. 1994 Oct;165(2):574-84.

PMID:
7958423
6.

Long-distance control of origin choice and replication timing in the human beta-globin locus are independent of the locus control region.

Cimbora DM, Schübeler D, Reik A, Hamilton J, Francastel C, Epner EM, Groudine M.

Mol Cell Biol. 2000 Aug;20(15):5581-91.

7.

The human beta-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene.

Tewari R, Gillemans N, Harper A, Wijgerde M, Zafarana G, Drabek D, Grosveld F, Philipsen S.

Development. 1996 Dec;122(12):3991-9.

8.

Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.

Bungert J, Davé U, Lim KC, Lieuw KH, Shavit JA, Liu Q, Engel JD.

Genes Dev. 1995 Dec 15;9(24):3083-96.

9.

Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.

Ellis J, Pasceri P, Tan-Un KC, Wu X, Harper A, Fraser P, Grosveld F.

Nucleic Acids Res. 1997 Mar 15;25(6):1296-302.

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Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.

Hug BA, Wesselschmidt RL, Fiering S, Bender MA, Epner E, Groudine M, Ley TJ.

Mol Cell Biol. 1996 Jun;16(6):2906-12.

13.

Sequences located 3' to the breakpoint of the hereditary persistence of fetal hemoglobin-3 deletion exhibit enhancer activity and can modify the developmental expression of the human fetal A gamma-globin gene in transgenic mice.

Anagnou NP, Perez-Stable C, Gelinas R, Costantini F, Liapaki K, Constantopoulou M, Kosteas T, Moschonas NK, Stamatoyannopoulos G.

J Biol Chem. 1995 Apr 28;270(17):10256-63.

14.

Human gamma-globin gene promoter element regulates human beta-globin gene developmental specificity.

Ryan TM, Sun CW, Ren J, Townes TM.

Nucleic Acids Res. 2000 Jul 15;28(14):2736-40.

15.

Effects of human locus control region elements HS2 and HS3 on human beta-globin gene expression in transgenic mouse.

Jia CP, Huang SZ, Yan JB, Xiao YP, Ren ZR, Zeng YT.

Blood Cells Mol Dis. 2003 Nov-Dec;31(3):360-9.

PMID:
14636653
16.

Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region.

Kim CG, Epner EM, Forrester WC, Groudine M.

Genes Dev. 1992 Jun;6(6):928-38.

17.

Regulated expression of the human beta globin gene in transgenic mice requires an upstream globin or nonglobin promoter.

Anderson KP, Lloyd JA, Ponce E, Crable SC, Neumann JC, Lingrel JB.

Mol Biol Cell. 1993 Oct;4(10):1077-85.

18.

Targeted deletion of 5'HS1 and 5'HS4 of the beta-globin locus control region reveals additive activity of the DNaseI hypersensitive sites.

Bender MA, Roach JN, Halow J, Close J, Alami R, Bouhassira EE, Groudine M, Fiering SN.

Blood. 2001 Oct 1;98(7):2022-7.

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