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Results: 1 to 20 of 389

1.

L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides.

Ye B, Akamatsu M, Shoelson SE, Wolf G, Giorgetti-Peraldi S, Yan X, Roller PP, Burke TR Jr.

J Med Chem. 1995 Oct 13;38(21):4270-5.

PMID:
7473554
[PubMed - indexed for MEDLINE]
2.

4'-O-[2-(2-fluoromalonyl)]-L-tyrosine: a phosphotyrosyl mimic for the preparation of signal transduction inhibitory peptides.

Burke TR Jr, Ye B, Akamatsu M, Ford H Jr, Yan X, Kole HK, Wolf G, Shoelson SE, Roller PP.

J Med Chem. 1996 Mar 1;39(5):1021-7.

PMID:
8676336
[PubMed - indexed for MEDLINE]
3.

Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.

Burke TR Jr, Smyth MS, Otaka A, Nomizu M, Roller PP, Wolf G, Case R, Shoelson SE.

Biochemistry. 1994 May 31;33(21):6490-4.

PMID:
7515682
[PubMed - indexed for MEDLINE]
4.

Conformationally constrained phosphotyrosyl mimetics designed as monomeric Src homology 2 domain inhibitors.

Burke TR Jr, Barchi JJ Jr, George C, Wolf G, Shoelson SE, Yan X.

J Med Chem. 1995 Apr 14;38(8):1386-96.

PMID:
7537333
[PubMed - indexed for MEDLINE]
5.

Protein-tyrosine phosphatase inhibition by a peptide containing the phosphotyrosyl mimetic, L-O-malonyltyrosine.

Kole HK, Akamatsu M, Ye B, Yan X, Barford D, Roller PP, Burke TR Jr.

Biochem Biophys Res Commun. 1995 Apr 26;209(3):817-22.

PMID:
7537500
[PubMed - indexed for MEDLINE]
6.

N-terminal carboxyl and tetrazole-containing amides as adjuvants to Grb2 SH2 domain ligand binding.

Burke TR Jr, Yao ZJ, Gao Y, Wu JX, Zhu X, Luo JH, Guo R, Yang D.

Bioorg Med Chem. 2001 Jun;9(6):1439-45.

PMID:
11408162
[PubMed - indexed for MEDLINE]
7.

Inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands. 2. 4-(2-Malonyl)phenylalanine as a potent phosphotyrosyl mimetic.

Gao Y, Luo J, Yao ZJ, Guo R, Zou H, Kelley J, Voigt JH, Yang D, Burke TR Jr.

J Med Chem. 2000 Mar 9;43(5):911-20.

PMID:
10715157
[PubMed - indexed for MEDLINE]
8.

Potent inhibition of insulin receptor dephosphorylation by a hexamer peptide containing the phosphotyrosyl mimetic F2Pmp.

Burke TR Jr, Kole HK, Roller PP.

Biochem Biophys Res Commun. 1994 Oct 14;204(1):129-34.

PMID:
7524496
[PubMed - indexed for MEDLINE]
9.

Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives.

Song YL, Peach ML, Roller PP, Qiu S, Wang S, Long YQ.

J Med Chem. 2006 Mar 9;49(5):1585-96.

PMID:
16509576
[PubMed - indexed for MEDLINE]
10.

Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.

Burke TR Jr, Yao ZJ, Liu DG, Voigt J, Gao Y.

Biopolymers. 2001;60(1):32-44. Review.

PMID:
11376431
[PubMed - indexed for MEDLINE]
11.

Incorporation of phosphotyrosyl mimetic 4-(phosphonodifluoromethyl)phenylalanine (F2Pmp) into signal transduction-directed peptides.

Yao ZJ, Lee K, Burke TR Jr.

Methods Mol Biol. 2005;298:91-103.

PMID:
16044542
[PubMed - indexed for MEDLINE]
12.

Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands.

Yao ZJ, King CR, Cao T, Kelley J, Milne GW, Voigt JH, Burke TR Jr.

J Med Chem. 1999 Jan 14;42(1):25-35.

PMID:
9888830
[PubMed - indexed for MEDLINE]
13.

Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1.

Sugimoto S, Wandless TJ, Shoelson SE, Neel BG, Walsh CT.

J Biol Chem. 1994 May 6;269(18):13614-22.

PMID:
7513703
[PubMed - indexed for MEDLINE]
Free Article
14.
15.

Nonphosphorylated peptide ligands for the Grb2 Src homology 2 domain.

Oligino L, Lung FD, Sastry L, Bigelow J, Cao T, Curran M, Burke TR Jr, Wang S, Krag D, Roller PP, King CR.

J Biol Chem. 1997 Nov 14;272(46):29046-52.

PMID:
9360978
[PubMed - indexed for MEDLINE]
Free Article
16.

Design of tetrapeptide ligands as inhibitors of the Src SH2 domain.

Nam NH, Pitts RL, Sun G, Sardari S, Tiemo A, Xie M, Yan B, Parang K.

Bioorg Med Chem. 2004 Feb 15;12(4):779-87.

PMID:
14759738
[PubMed - indexed for MEDLINE]
17.

Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck.

Eck MJ, Shoelson SE, Harrison SC.

Nature. 1993 Mar 4;362(6415):87-91.

PMID:
7680435
[PubMed - indexed for MEDLINE]
18.
19.

Direct determination of the sequence recognition requirements of the SH2 domains of SH-PTP2.

Huyer G, Li ZM, Adam M, Huckle WR, Ramachandran C.

Biochemistry. 1995 Jan 24;34(3):1040-9.

PMID:
7530043
[PubMed - indexed for MEDLINE]
20.

Design and synthesis of phosphonodifluoromethyl phenylalanine (F2Pmp): a useful phosphotyrosyl mimetic.

Burke TR Jr.

Curr Top Med Chem. 2006;6(14):1465-71. Review.

PMID:
16918462
[PubMed - indexed for MEDLINE]

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