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Items: 1 to 20 of 176

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Dihydroxynitrobenzaldehydes and hydroxymethoxynitrobenzaldehydes: synthesis and biological activity as catechol-O-methyltransferase inhibitors.

Pérez RA, Fernández-Alvarez E, Nieto O, Piedrafita FJ.

J Med Chem. 1992 Nov 27;35(24):4584-8.

PMID:
1469689
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Structure-based design, synthesis, and in vitro evaluation of bisubstrate inhibitors for catechol O-methyltransferase (COMT).

Masjost B, Ballmer P, Borroni E, Zürcher G, Winkler FK, Jakob-Roetne R, Diederich F.

Chemistry. 2000 Mar 17;6(6):971-82.

PMID:
10785817
7.

Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors.

Bäckström R, Honkanen E, Pippuri A, Kairisalo P, Pystynen J, Heinola K, Nissinen E, Linden IB, Männistö PT, Kaakkola S, et al.

J Med Chem. 1989 Apr;32(4):841-6.

PMID:
2704029
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Catechol O-methyltransferase. 8. Structure-activity relationships for inhibtion by 8-hydroxyquinolines.

Borchardt RT, Thakker DR, Warner VD, Mirth DB, Sane JN.

J Med Chem. 1976 Apr;19(4):558-60.

PMID:
817025
10.

Inhibition of rat liver catechol-O-methyltransferase by lanthanum. neodymium and europium.

Quiram DR, Weinshilboum RM.

Biochem Pharmacol. 1976 Aug 1;25(15):1727-32. No abstract available.

PMID:
942475
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Catechol O-methyltransferase. 2. In vitro inhibition by substituted 8-hydroxyquinolines.

Borchardt RT.

J Med Chem. 1973 Apr;16(4):382-7. No abstract available.

PMID:
4736750
16.

PLS modelling of structure-activity relationships of catechol O-methyltransferase inhibitors.

Lotta T, Taskinen J, Bäckström R, Nissinen E.

J Comput Aided Mol Des. 1992 Jun;6(3):253-72.

PMID:
1517777
17.

Synthesis and biological activity of 2- and 4-substituted 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines.

Smissman EE, Reid JR, Walsh DA, Borchardt RT.

J Med Chem. 1976 Jan;19(1):127-31.

PMID:
1246034
18.

Catechol-O-methyltransferase. II. A new class of inhibitors of catechol-o-methyltransferase; 3,5-dihydroxy-4-methoxybenzoic acid and related compounds.

Nikodejevic B, Senoh S, Daly JW, Creveling CR.

J Pharmacol Exp Ther. 1970 Jul;174(1):83-93. No abstract available.

PMID:
5432229
19.

[O-Methylation of epinephrine, 3,4-dihydroxybenzoic acid and 6,7-dihydroxycoumarin in yeasts (author's transl)].

Müller-Enoch D, Thomas H, Streng W, Wildfeuer W, Haferkamp O.

Z Naturforsch C. 1976 Sep-Oct;31(9-10):509-13. German.

PMID:
136120
20.

Dehydrodicaffeic acid dilactone, an inhibitor of catechol-O-methyl transferase.

Kumada Y, Naganawa H, Iinuma H, Matsuzaki M, Takeuchi T.

J Antibiot (Tokyo). 1976 Sep;29(9):882-9.

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