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Similar articles for PMID: 27982047

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Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.
Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA Jr, Moaddel R, Traynelis SF, Pereira EFR, Thompson SM, Albuquerque EX, Gould TD. Lumsden EW, et al. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5160-5169. doi: 10.1073/pnas.1816071116. Epub 2019 Feb 22. Proc Natl Acad Sci U S A. 2019. PMID: 30796190 Free PMC article.
(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression.
Yokoyama R, Higuchi M, Tanabe W, Tsukada S, Naito M, Yamaguchi T, Chen L, Kasai A, Seiriki K, Nakazawa T, Nakagawa S, Hashimoto K, Hashimoto H, Ago Y. Yokoyama R, et al. Pharmacol Biochem Behav. 2020 Apr;191:172876. doi: 10.1016/j.pbb.2020.172876. Epub 2020 Feb 20. Pharmacol Biochem Behav. 2020. PMID: 32088360
Mechanisms of ketamine action as an antidepressant.
Zanos P, Gould TD. Zanos P, et al. Mol Psychiatry. 2018 Apr;23(4):801-811. doi: 10.1038/mp.2017.255. Epub 2018 Mar 13. Mol Psychiatry. 2018. PMID: 29532791 Free PMC article. Review.
83 results