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Should we exclude acute stroke patients with previous intracerebral hemorrhage from receiving intravenous thrombolysis?

Lee SH, Kim BJ, Han MK, Park TH, Lee KB, Lee BC, Yu KH, Oh MS, Cha JK, Kim DH, Nah HW, Lee J, Lee SJ, Ko Y, Kim JG, Park JM, Kang K, Cho YJ, Hong KS, Choi JC, Kim JT, Choi K, Kim DE, Ryu WS, Kim WJ, Shin DI, Yeo M, Lee J, Lee JS, Gorelick PB, Bae HJ. Lee SH, et al. Int J Stroke. 2016 Oct;11(7):783-90. doi: 10.1177/1747493016654289. Epub 2016 Jun 16. Int J Stroke. 2016. PMID: 27312681

Remote Intracerebral Hemorrhage After Intravenous Thrombolysis: Results From a Multicenter Study.

Prats-Sánchez L, Camps-Renom P, Sotoca-Fernández J, Delgado-Mederos R, Martínez-Domeño A, Marín R, Almendrote M, Dorado L, Gomis M, Codas J, Llull L, Gómez González A, Roquer J, Purroy F, Gómez-Choco M, Cánovas D, Cocho D, Garces M, Abilleira S, Martí-Fàbregas J; Catalan Stroke Code and Reperfusion Consortium (Cat-SCR). Prats-Sánchez L, et al. Stroke. 2016 Aug;47(8):2003-9. doi: 10.1161/STROKEAHA.116.013952. Epub 2016 Jul 12. Stroke. 2016. PMID: 27406103

The THRIVE score predicts symptomatic intracerebral hemorrhage after intravenous tPA administration in SITS-MOST.

Flint AC, Gupta R, Smith WS, Kamel H, Faigeles BS, Cullen SP, Rao VA, Bath PM, Wahlgren N, Ahmed N, Donnan GA; SITS International and VISTA-plus investigators. Flint AC, et al. Int J Stroke. 2014 Aug;9(6):705-10. doi: 10.1111/ijs.12335. Epub 2014 Jul 15. Int J Stroke. 2014. PMID: 25042855

Two tales: hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is related to severity and duration of ischemia: MRI study of acute stroke patients treated with intravenous tissue plasminogen activator within 6 hours.

Thomalla G, Sobesky J, Köhrmann M, Fiebach JB, Fiehler J, Zaro Weber O, Kruetzelmann A, Kucinski T, Rosenkranz M, Röther J, Schellinger PD. Thomalla G, et al. Stroke. 2007 Feb;38(2):313-8. doi: 10.1161/01.STR.0000254565.51807.22. Epub 2007 Jan 4. Stroke. 2007. PMID: 17204683

Predictors of in-hospital death and symptomatic intracranial hemorrhage in patients with acute ischemic stroke treated with thrombolytic therapy: Paul Coverdell Acute Stroke Registry 2008-2012.

Tong X, George MG, Yang Q, Gillespie C. Tong X, et al. Int J Stroke. 2014 Aug;9(6):728-34. doi: 10.1111/ijs.12155. Epub 2013 Sep 12. Int J Stroke. 2014. PMID: 24024962 Free PMC article.

Remote or extraischemic intracerebral hemorrhage--an uncommon complication of stroke thrombolysis: results from the safe implementation of treatments in stroke-international stroke thrombolysis register.

Mazya MV, Ahmed N, Ford GA, Hobohm C, Mikulik R, Nunes AP, Wahlgren N; Scientific Committee of SITS International. Mazya MV, et al. Stroke. 2014 Jun;45(6):1657-63. doi: 10.1161/STROKEAHA.114.004923. Epub 2014 May 1. Stroke. 2014. PMID: 24788971 Clinical Trial.

Computed Tomography--Verified Leukoaraiosis Is a Risk Factor for Post-thrombolytic Hemorrhage.

Willer L, Havsteen I, Ovesen C, Christensen AF, Christensen H. Willer L, et al. J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1126-30. doi: 10.1016/j.jstrokecerebrovasdis.2014.12.018. Epub 2015 Apr 25. J Stroke Cerebrovasc Dis. 2015. PMID: 25920756

Symptomatic intracranial hemorrhage following intravenous thrombolysis for acute ischemic stroke: a critical review of case definitions.

Seet RC, Rabinstein AA. Seet RC, et al. Cerebrovasc Dis. 2012;34(2):106-14. doi: 10.1159/000339675. Epub 2012 Aug 1. Cerebrovasc Dis. 2012. PMID: 22868870 Free article. Review.

Severe renal impairment is associated with symptomatic intracerebral hemorrhage after thrombolysis for ischemic stroke.

Tütüncü S, Ziegler AM, Scheitz JF, Slowinski T, Rocco A, Endres M, Nolte CH. Tütüncü S, et al. Stroke. 2013 Nov;44(11):3217-9. doi: 10.1161/STROKEAHA.113.002859. Epub 2013 Sep 3. Stroke. 2013. PMID: 24003042

Comparison of combined venous and arterial thrombolysis with primary arterial therapy using recombinant tissue plasminogen activator in acute ischemic stroke.

Wolfe T, Suarez JI, Tarr RW, Welter E, Landis D, Sunshine JL, Zaidat OO. Wolfe T, et al. J Stroke Cerebrovasc Dis. 2008 May-Jun;17(3):121-8. doi: 10.1016/j.jstrokecerebrovasdis.2007.12.004. J Stroke Cerebrovasc Dis. 2008. PMID: 18436152

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