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Results: 1 to 20 of 112

1.

Effects of aging on insulin secretion.

Gumbiner B, Polonsky KS, Beltz WF, Wallace P, Brechtel G, Fink RI.

Diabetes. 1989 Dec;38(12):1549-56.

PMID:
2684711
[PubMed - indexed for MEDLINE]
2.

Quantitative study of insulin secretion and clearance in normal and obese subjects.

Polonsky KS, Given BD, Hirsch L, Shapiro ET, Tillil H, Beebe C, Galloway JA, Frank BH, Karrison T, Van Cauter E.

J Clin Invest. 1988 Feb;81(2):435-41.

PMID:
3276729
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The metabolic clearance of insulin and the feedback inhibition of insulin secretion are altered with aging.

Fink RI, Revers RR, Kolterman OG, Olefsky JM.

Diabetes. 1985 Mar;34(3):275-80.

PMID:
3882495
[PubMed - indexed for MEDLINE]
4.

Metabolic alterations in middle-aged and elderly obese patients with type 2 diabetes.

Meneilly GS, Elliott T.

Diabetes Care. 1999 Jan;22(1):112-8.

PMID:
10333911
[PubMed - indexed for MEDLINE]
Free Article
5.

Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation.

Blackman JD, Polonsky KS, Jaspan JB, Sturis J, Van Cauter E, Thistlethwaite JR.

Diabetes. 1992 Oct;41(10):1346-54.

PMID:
1397710
[PubMed - indexed for MEDLINE]
6.

Mechanisms of the age-associated deterioration in glucose tolerance: contribution of alterations in insulin secretion, action, and clearance.

Basu R, Breda E, Oberg AL, Powell CC, Dalla Man C, Basu A, Vittone JL, Klee GG, Arora P, Jensen MD, Toffolo G, Cobelli C, Rizza RA.

Diabetes. 2003 Jul;52(7):1738-48. Erratum in: Diabetes. 2003 Dec;52(12):3014.

PMID:
12829641
[PubMed - indexed for MEDLINE]
Free Article
7.

Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects.

Polonsky KS, Given BD, Van Cauter E.

J Clin Invest. 1988 Feb;81(2):442-8.

PMID:
3276730
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Effects of weight loss and reduced hyperglycemia on the kinetics of insulin secretion in obese non-insulin dependent diabetes mellitus.

Gumbiner B, Polonsky KS, Beltz WF, Griver K, Wallace P, Brechtel G, Henry RR.

J Clin Endocrinol Metab. 1990 Jun;70(6):1594-602.

PMID:
2189885
[PubMed - indexed for MEDLINE]
9.

Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans.

Tillil H, Shapiro ET, Rubenstein AH, Galloway JA, Polonsky KS.

Diabetes. 1988 Oct;37(10):1351-7.

PMID:
3046967
[PubMed - indexed for MEDLINE]
10.

A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes.

Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, Pratipanawatr W, Bajaj M, Mandarino L, DeFronzo R, Cusi K.

Diabetes. 2003 Oct;52(10):2461-74.

PMID:
14514628
[PubMed - indexed for MEDLINE]
Free Article
11.

The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus.

Garvey WT, Olefsky JM, Griffin J, Hamman RF, Kolterman OG.

Diabetes. 1985 Mar;34(3):222-34.

PMID:
3882489
[PubMed - indexed for MEDLINE]
12.

Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance.

Van Cauter E, Mestrez F, Sturis J, Polonsky KS.

Diabetes. 1992 Mar;41(3):368-77.

PMID:
1551497
[PubMed - indexed for MEDLINE]
13.

Mechanisms of insulin resistance in aging.

Fink RI, Kolterman OG, Griffin J, Olefsky JM.

J Clin Invest. 1983 Jun;71(6):1523-35.

PMID:
6345584
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Day-long integrated serum insulin and C-peptide profiles in patients with NIDDM. Correlation with urinary C-peptide excretion.

Garvey WT, Olefsky JM, Rubenstein AH, Kolterman OG.

Diabetes. 1988 May;37(5):590-9.

PMID:
3282946
[PubMed - indexed for MEDLINE]
15.

Human aging is associated with altered TNF-alpha production during hyperglycemia and hyperinsulinemia.

Kirwan JP, Krishnan RK, Weaver JA, Del Aguila LF, Evans WJ.

Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1137-43.

PMID:
11701426
[PubMed - indexed for MEDLINE]
Free Article
16.

Elevated basal insulin secretion and normal dynamic insulin sensitivity in borderline hypertension.

Piccardo MG, Turchetti G, Rosa MS, Pacini G.

Nutr Metab Cardiovasc Dis. 1999 Oct;9(5):244-9.

PMID:
10656171
[PubMed - indexed for MEDLINE]
17.

Age-related differences in the pancreatic beta-cell response to hyperglycemia after eccentric exercise.

Krishnan RK, Hernandez JM, Williamson DL, O'Gorman DJ, Evans WJ, Kirwan JP.

Am J Physiol. 1998 Sep;275(3 Pt 1):E463-70.

PMID:
9725813
[PubMed - indexed for MEDLINE]
Free Article
18.

Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.

Meier JJ, Nauck MA, Siepmann N, Greulich M, Holst JJ, Deacon CF, Schmidt WE, Gallwitz B.

Metabolism. 2003 Dec;52(12):1579-85.

PMID:
14669159
[PubMed - indexed for MEDLINE]
19.

Insulin sensitivity and secretion in healthy elderly human subjects with 'abnormal' glucose tolerance.

Broughton DL, Webster J, Taylor R.

Eur J Clin Invest. 1992 Sep;22(9):582-90.

PMID:
1459175
[PubMed - indexed for MEDLINE]
20.

Effects of age and sex on postprandial glucose metabolism: differences in glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction.

Basu R, Dalla Man C, Campioni M, Basu A, Klee G, Toffolo G, Cobelli C, Rizza RA.

Diabetes. 2006 Jul;55(7):2001-14. Erratum in: Diabetes. 2006 Sep;55(9):2665.

PMID:
16804069
[PubMed - indexed for MEDLINE]
Free Article

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