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26226997,29794081,26724488,31171282,24998121,27587437,26088300,27706224,27207998,23338902,29103847,26627989,28744335,24315724,31230500,31752643,23575978,23325525,34459659,36448417,30385030,27307517,23583249,23500276,28720644,27534868,25579887,23698729,22041550,28029216,29339165,27343417,27771552,21207345,31479160,26070218,29101289,31520437,23150654,21242484,24986568,25912470,27139910,24687964,24291776,25773559,26324517,30305484,28215062,26698882,27262782,27797888,28730948,26335602,34740490,25711953,25060590,18180653,26838691,29526284,24076495,33632432,22684583,29453694,31055767,23391196,26306127,24327462,26492310,27474824,35933600,29970321,29526288,23790602,22494863,30962008,27412905,27225288,22912382,36180856,28679480,25399274,26318322,35969865,27495048,23973952,22450212,23931100,24200350,27581874,24715600,26616031,35872052,28625383,30041779,27571335,25559429,24798956,36400415,27199213,23252940,23659614,27870603,26335355,25298359,17347079,22827490,31036510,23870607,27547142,34668395,35512918,30088015,33903038,35060062,29526285,26401923,33687872,29274758,16034869,22286325,31721242,31710249,30857852,28545622,31959803,26516013,29495123,26516014,26088301,32941819,25634169,27898435,31088992,24650403,34192400,33189659,24400656,34371269,24998122,26935273,29526289,20544311,35488947,29526286,29759681,37076229,29228158,27426862,29143099,27769175,30483820,31774244,29680999,31092194,32755246,32504227,32323386,33423538,30322987,31076823,17577005,30931494,33376457,24315113,36270714,30758149,32728781,33315494,25332279,27161800,34547386,24217039,25791094,34669950,35361462,30171381,35918658,32067649,34582384,22539099,32535831,33999547,32643392,35512858,26561858,24260914,27560191,32910248,30777320,31714267,30376971,34565167,20356712,25975727,33259077,28256020,11386894,29526283,35467950,36336589,29728202,32024807,26717376,36257480,35469679,33110242,29628346,35515958,15604851,32975310,26914668,35467313,30994632,22949772,32439033,35194833,27816552,30573129,19901203,35801485,25147042,25786799,33264172,27957099,34281383,29411147,36352853,35373133,10356600,35369701,34706552,30594462,15610642,29903352,35467955,35467951,31474327,10230745,34798204,32583806,34664871,33022393,31184324,23184098,12839044,27816551,29718897,19901202,35655531,35490708,32778338,12515765,30724905,37076223,30855029,24638951,29185096,19589108,28033129,32459024,34830548,10632303,31171277,34949402,25997369,8067177,29739702,12352765,33722871,29739916,33413868,31360545,11176219,34338069,23036629,33272374,30982541,33334455,30712419,29796644,30072184,33155356,32067639,33576934,33072447,30182193,28888264,34218244,23846737,36940461,36940460,34919089,27729341,26203535,33516402,31951209,30704390,29453212,35523426,23965351,27729343,25894049,7823406,24534937,29782263,36340489,23909526,11239205,35981847,31599452,32445494,22304704,35644502,29071390,26616032,25876258,25837463,35969862,28847595,28799239,31351665,25717354,33249962,25277828,32709261,34580019,26166308,29530891,36286828,35959676,29104013,17938402,30562066,25080281,33413808,32259588,8552791,30249440,36357019,35506326,32583229,19721024,31573090,34793880,32495476,30209635,31876019,30354435,22286319,34955481,29122134,30459610,34949422,30354436,36008163,23421469,36245073,22923145,30671252,35869889,29706394,30745410,32238317,36378728,36357017,30391408,25463362,26738660,25756445,31996870,25756446,28296586,30309224,11342504,33210874,30398962,25227869,26738662,27894774,27345609,27619330,35521808,26627990,31522766,21599901,30939907,34387565,30119276,36890047,27307520,27625372,31898985,30112826,28690086,31779799,30742754,34412802,28081965,9490603,30834801,33203786,26309492,31473150,28104479,30318135,29454418,35393109,31531241,28320002,35819038,23647927,27194542,34496623,28259717,15954239,26994984,29197455,28181272,23398659,31877589,29917150,23551993,27462678,29759665,24281558,31865973,32766107,36514614,34991818,31889597,33274311,31691754,33809503,33851790,27544592,27125946,15008908,31092166,36538772,28496851,31090369,31672194,31672195,29487677,29759669,19204836,25732359,27557552,25402537,35969860,23204530,25301456,35002374,29399959,27957060,31648708,31267868,27388827,30240797,30871696,35365423,30398968,37130436,28242017,29153742,32498768,9734668,27199231,27858955,33906461,19399825,31352454,24790796,28187921,22727967,24986048,23172099,27609679,29607896,27931603,27719817,27470454,34300202,32135563,23251767,28807266,31226209,29960621,24773694,24005804,26764080,29960622,32250429,32224751,29607970,27151355,31033777,27151357,32528755,29051130,29798788,28512110,26049978,27240611,27091741,30112285,35830102,29779641,30753396,28881467,30576878,24493527,24394841,10525970,27659461,29759667,37100537,31539052,28466849,29051131,28658488,30819361,24493526,32060537,29998323,32082838,29024070,29056959,32943161,29797287,12911602,27478118,1531880,31912886,30652322,30485047,30592661,27101916,31913502,25253879,25224531,28254413,32240483,30846108,32460400,28466847,22550762,36876251,32563524,30575892,30334180,35976601,34604803,30500883,28213369,27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Results by year

Year	Number of Results
1992	1
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726 results

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Left Atrial Appendage Occlusion Device and Novel Oral Anticoagulants Versus Warfarin for Stroke Prevention in Nonvalvular Atrial Fibrillation: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Briceno DF, Villablanca P, Cyrille N, Massera D, Bader E, Manheimer E, Aagaard P, Ferrick K, Gross J, Kim SG, Krumerman A, Palma E, Guttenplan N, Romero J, Fisher J, Garcia M, Natale A, Di Biase L. Briceno DF, et al. Circ Arrhythm Electrophysiol. 2015 Oct;8(5):1057-64. doi: 10.1161/CIRCEP.115.002993. Epub 2015 Jul 30. Circ Arrhythm Electrophysiol. 2015. PMID: 26226997 Review.

Periprocedural Outcomes of Direct Oral Anticoagulants Versus Warfarin in Nonvalvular Atrial Fibrillation.

Nazha B, Pandya B, Cohen J, Zhang M, Lopes RD, Garcia DA, Sherwood MW, Spyropoulos AC. Nazha B, et al. Circulation. 2018 Oct 2;138(14):1402-1411. doi: 10.1161/CIRCULATIONAHA.117.031457. Circulation. 2018. PMID: 29794081

Over 1-year efficacy and safety of left atrial appendage occlusion versus novel oral anticoagulants for stroke prevention in atrial fibrillation: A systematic review and meta-analysis of randomized controlled trials and observational studies.

Li X, Wen SN, Li SN, Bai R, Liu N, Feng L, Ruan YF, Du X, Dong JZ, Ma CS. Li X, et al. Heart Rhythm. 2016 Jun;13(6):1203-14. doi: 10.1016/j.hrthm.2015.12.037. Epub 2015 Dec 24. Heart Rhythm. 2016. PMID: 26724488 Review.

Propensity-Matched Comparison of Oral Anticoagulation Versus Antiplatelet Therapy After Left Atrial Appendage Closure With WATCHMAN.

Søndergaard L, Wong YH, Reddy VY, Boersma LVA, Bergmann MW, Doshi S, Kar S, Sievert H, Wehrenberg S, Stein K, Holmes DR Jr. Søndergaard L, et al. JACC Cardiovasc Interv. 2019 Jun 10;12(11):1055-1063. doi: 10.1016/j.jcin.2019.04.004. JACC Cardiovasc Interv. 2019. PMID: 31171282 Free article.

Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial.

Holmes DR Jr, Kar S, Price MJ, Whisenant B, Sievert H, Doshi SK, Huber K, Reddy VY. Holmes DR Jr, et al. J Am Coll Cardiol. 2014 Jul 8;64(1):1-12. doi: 10.1016/j.jacc.2014.04.029. J Am Coll Cardiol. 2014. PMID: 24998121 Free article. Clinical Trial.

Efficacy and safety of left atrial appendage closure versus medical treatment in atrial fibrillation: a network meta-analysis from randomised trials.

Sahay S, Nombela-Franco L, Rodes-Cabau J, Jimenez-Quevedo P, Salinas P, Biagioni C, Nuñez-Gil I, Gonzalo N, de Agustín JA, Del Trigo M, Perez de Isla L, Fernández-Ortiz A, Escaned J, Macaya C. Sahay S, et al. Heart. 2017 Jan 15;103(2):139-147. doi: 10.1136/heartjnl-2016-309782. Epub 2016 Sep 1. Heart. 2017. PMID: 27587437

Left Atrial Appendage Closure as an Alternative to Warfarin for Stroke Prevention in Atrial Fibrillation: A Patient-Level Meta-Analysis.

Holmes DR Jr, Doshi SK, Kar S, Price MJ, Sanchez JM, Sievert H, Valderrabano M, Reddy VY. Holmes DR Jr, et al. J Am Coll Cardiol. 2015 Jun 23;65(24):2614-2623. doi: 10.1016/j.jacc.2015.04.025. J Am Coll Cardiol. 2015. PMID: 26088300 Free article.

Comparison of Approaches for Stroke Prophylaxis in Patients with Non-Valvular Atrial Fibrillation: Network Meta-Analyses of Randomized Controlled Trials.

Bajaj NS, Kalra R, Patel N, Hashim T, Godara H, Ather S, Arora G, Pasala T, Whitfield TT, McGiffin DC, Ahmed MI, Lloyd SG, Limdi NA, Arora P. Bajaj NS, et al. PLoS One. 2016 Oct 5;11(10):e0163608. doi: 10.1371/journal.pone.0163608. eCollection 2016. PLoS One. 2016. PMID: 27706224 Free PMC article.

Comparative Effectiveness of Interventions for Stroke Prevention in Atrial Fibrillation: A Network Meta-Analysis.

Tereshchenko LG, Henrikson CA, Cigarroa J, Steinberg JS. Tereshchenko LG, et al. J Am Heart Assoc. 2016 May 20;5(5):e003206. doi: 10.1161/JAHA.116.003206. J Am Heart Assoc. 2016. PMID: 27207998 Free PMC article.

Novel oral anticoagulants in atrial fibrillation: a meta-analysis of large, randomized, controlled trials vs warfarin.

Dogliotti A, Paolasso E, Giugliano RP. Dogliotti A, et al. Clin Cardiol. 2013 Feb;36(2):61-7. doi: 10.1002/clc.22081. Epub 2013 Jan 21. Clin Cardiol. 2013. PMID: 23338902 Free PMC article. Review.

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