Similar articles for PMID: 25677495

Year	Number of Results
2009	2
2010	4
2011	3
2012	7
2013	5
2014	11
2015	16
2016	9
2017	7
2021	1
2022	1
2024	0

1

Effectively targeting CRAF: rational serendipity targeting SRC?

Flaherty KT. Flaherty KT. Pigment Cell Melanoma Res. 2015 May;28(3):242-3. doi: 10.1111/pcmr.12360. Epub 2015 Mar 4. Pigment Cell Melanoma Res. 2015. PMID: 25677495 No abstract available.

2

Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma.

Girotti MR, Lopes F, Preece N, Niculescu-Duvaz D, Zambon A, Davies L, Whittaker S, Saturno G, Viros A, Pedersen M, Suijkerbuijk BM, Menard D, McLeary R, Johnson L, Fish L, Ejiama S, Sanchez-Laorden B, Hohloch J, Carragher N, Macleod K, Ashton G, Marusiak AA, Fusi A, Brognard J, Frame M, Lorigan P, Marais R, Springer C. Girotti MR, et al. Cancer Cell. 2015 Jan 12;27(1):85-96. doi: 10.1016/j.ccell.2014.11.006. Epub 2014 Dec 11. Cancer Cell. 2015. PMID: 25500121 Free PMC article.

3

Hepatocyte growth factor in the neighborhood reverses resistance to BRAF inhibitor in melanoma.

Nickoloff BJ, Vande Woude G. Nickoloff BJ, et al. Pigment Cell Melanoma Res. 2012 Nov;25(6):758-61. doi: 10.1111/pcmr.12020. Pigment Cell Melanoma Res. 2012. PMID: 22974232 No abstract available.

4

LY3009120, a panRAF inhibitor, has significant anti-tumor activity in BRAF and KRAS mutant preclinical models of colorectal cancer.

Vakana E, Pratt S, Blosser W, Dowless M, Simpson N, Yuan XJ, Jaken S, Manro J, Stephens J, Zhang Y, Huber L, Peng SB, Stancato LF. Vakana E, et al. Oncotarget. 2017 Feb 7;8(6):9251-9266. doi: 10.18632/oncotarget.14002. Oncotarget. 2017. PMID: 27999210 Free PMC article.

5

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.

Peng SB, Henry JR, Kaufman MD, Lu WP, Smith BD, Vogeti S, Rutkoski TJ, Wise S, Chun L, Zhang Y, Van Horn RD, Yin T, Zhang X, Yadav V, Chen SH, Gong X, Ma X, Webster Y, Buchanan S, Mochalkin I, Huber L, Kays L, Donoho GP, Walgren J, McCann D, Patel P, Conti I, Plowman GD, Starling JJ, Flynn DL. Peng SB, et al. Cancer Cell. 2015 Sep 14;28(3):384-98. doi: 10.1016/j.ccell.2015.08.002. Epub 2015 Sep 3. Cancer Cell. 2015. PMID: 26343583 Free article.

6

Design, synthesis and biological evaluation of benzyl 2-(1H-imidazole-1-yl) pyrimidine analogues as selective and potent Raf inhibitors.

Kim M, Lee J, Jung K, Kim H, Aman W, Ryu JS, Hah JM. Kim M, et al. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3600-4. doi: 10.1016/j.bmcl.2014.05.030. Epub 2014 May 17. Bioorg Med Chem Lett. 2014. PMID: 24878193

7

Antitumor activity of the selective pan-RAF inhibitor TAK-632 in BRAF inhibitor-resistant melanoma.

Nakamura A, Arita T, Tsuchiya S, Donelan J, Chouitar J, Carideo E, Galvin K, Okaniwa M, Ishikawa T, Yoshida S. Nakamura A, et al. Cancer Res. 2013 Dec 1;73(23):7043-55. doi: 10.1158/0008-5472.CAN-13-1825. Epub 2013 Oct 11. Cancer Res. 2013. PMID: 24121489

8

Efficacy of vemurafenib in a trametinib-resistant stage IV melanoma patient--letter.

Bernhardt M, Orouji E, Larribere L, Gebhardt C, Utikal J. Bernhardt M, et al. Clin Cancer Res. 2014 May 1;20(9):2498-9. doi: 10.1158/1078-0432.CCR-13-2349. Clin Cancer Res. 2014. PMID: 24789037 No abstract available.

9

A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib.

Graziani G, Artuso S, De Luca A, Muzi A, Rotili D, Scimeca M, Atzori MG, Ceci C, Mai A, Leonetti C, Levati L, Bonanno E, Tentori L, Caccuri AM. Graziani G, et al. Biochem Pharmacol. 2015 May 1;95(1):16-27. doi: 10.1016/j.bcp.2015.03.004. Epub 2015 Mar 17. Biochem Pharmacol. 2015. PMID: 25795251

10

Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance.

Wang L, Zhu G, Zhang Q, Duan C, Zhang Y, Zhang Z, Zhou Y, Lu T, Tang W. Wang L, et al. Org Biomol Chem. 2017 Apr 18;15(16):3455-3465. doi: 10.1039/c7ob00518k. Org Biomol Chem. 2017. PMID: 28368067

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