Similar articles for PMID: 25589936

Year	Number of Results
1988	1
1990	1
1995	1
1997	3
1998	2
2000	4
2001	4
2002	4
2003	3
2005	1
2006	1
2007	2
2008	2
2009	4
2010	3
2011	2
2013	4
2014	7
2015	6
2016	6
2017	10
2018	9
2019	13
2020	3
2024	0

1

Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma.

Harrison BA, Almstead ZY, Burgoon H, Gardyan M, Goodwin NC, Healy J, Liu Y, Mabon R, Marinelli B, Samala L, Zhang Y, Stouch TR, Whitlock NA, Gopinathan S, McKnight B, Wang S, Patel N, Wilson AG, Hamman BD, Rice DS, Rawlins DB. Harrison BA, et al. ACS Med Chem Lett. 2014 Nov 24;6(1):84-8. doi: 10.1021/ml500367g. eCollection 2015 Jan 8. ACS Med Chem Lett. 2014. PMID: 25589936 Free PMC article.

2

Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.

Harrison BA, Whitlock NA, Voronkov MV, Almstead ZY, Gu KJ, Mabon R, Gardyan M, Hamman BD, Allen J, Gopinathan S, McKnight B, Crist M, Zhang Y, Liu Y, Courtney LF, Key B, Zhou J, Patel N, Yates PW, Liu Q, Wilson AG, Kimball SD, Crosson CE, Rice DS, Rawlins DB. Harrison BA, et al. J Med Chem. 2009 Nov 12;52(21):6515-8. doi: 10.1021/jm901226j. J Med Chem. 2009. PMID: 19831390

3

Rho-kinase (ROCK) Inhibitors - A Neuroprotective Therapeutic Paradigm with a Focus on Ocular Utility.

Abbhi V, Piplani P. Abbhi V, et al. Curr Med Chem. 2020;27(14):2222-2256. doi: 10.2174/0929867325666181031102829. Curr Med Chem. 2020. PMID: 30378487 Review.

4

Intraocular pressure-lowering effects of imidazo[1,2-a]- and pyrimido[1,2-a]benzimidazole compounds in rats with dexamethasone-induced ocular hypertension.

Marcus AJ, Iezhitsa I, Agarwal R, Vassiliev P, Spasov A, Zhukovskaya O, Anisimova V, Ismail NM. Marcus AJ, et al. Eur J Pharmacol. 2019 May 5;850:75-87. doi: 10.1016/j.ejphar.2019.01.059. Epub 2019 Feb 1. Eur J Pharmacol. 2019. PMID: 30716317

5

Discovery of Potent and Selective Urea-Based ROCK Inhibitors and Their Effects on Intraocular Pressure in Rats.

Yin Y, Cameron MD, Lin L, Khan S, Schröter T, Grant W, Pocas J, Chen YT, Schürer S, Pachori A, LoGrasso P, Feng Y. Yin Y, et al. ACS Med Chem Lett. 2010 Apr 5;1(4):175-9. doi: 10.1021/ml1000382. eCollection 2010 Jul 8. ACS Med Chem Lett. 2010. PMID: 24900192 Free PMC article.

6

AMA0076, a novel, locally acting Rho kinase inhibitor, potently lowers intraocular pressure in New Zealand white rabbits with minimal hyperemia.

Van de Velde S, Van Bergen T, Sijnave D, Hollanders K, Castermans K, Defert O, Leysen D, Vandewalle E, Moons L, Stalmans I. Van de Velde S, et al. Invest Ophthalmol Vis Sci. 2014 Feb 18;55(2):1006-16. doi: 10.1167/iovs.13-13157. Invest Ophthalmol Vis Sci. 2014. PMID: 24474276 Free article.

7

Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma.

Sturdivant JM, Royalty SM, Lin CW, Moore LA, Yingling JD, Laethem CL, Sherman B, Heintzelman GR, Kopczynski CC, deLong MA. Sturdivant JM, et al. Bioorg Med Chem Lett. 2016 May 15;26(10):2475-2480. doi: 10.1016/j.bmcl.2016.03.104. Epub 2016 Apr 1. Bioorg Med Chem Lett. 2016. PMID: 27072905

8

Rho-associated kinase inhibitors: a novel glaucoma therapy.

Inoue T, Tanihara H. Inoue T, et al. Prog Retin Eye Res. 2013 Nov;37:1-12. doi: 10.1016/j.preteyeres.2013.05.002. Epub 2013 Jun 12. Prog Retin Eye Res. 2013. PMID: 23770081 Review.

9

Impact of the clinical use of ROCK inhibitor on the pathogenesis and treatment of glaucoma.

Honjo M, Tanihara H. Honjo M, et al. Jpn J Ophthalmol. 2018 Mar;62(2):109-126. doi: 10.1007/s10384-018-0566-9. Epub 2018 Feb 14. Jpn J Ophthalmol. 2018. PMID: 29445943 Review.

10

A Rho-Associated Kinase Inhibitor Protects Permeability in a Cell Culture Model of Ocular Disease, and Reduces Aqueous Flare in Anterior Uveitis.

Yamada H, Yoneda M, Inaguma S, Gosho M, Murasawa Y, Isogai Z, Zako M. Yamada H, et al. J Ocul Pharmacol Ther. 2017 Apr;33(3):176-185. doi: 10.1089/jop.2016.0085. Epub 2017 Feb 3. J Ocul Pharmacol Ther. 2017. PMID: 28157424

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

85 results

Results by year