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Glucosamine enhances body weight gain and reduces insulin response in mice fed chow diet but mitigates obesity, insulin resistance and impaired glucose tolerance in mice high-fat diet.

Hwang JS, Park JW, Nam MS, Cho H, Han IO. Hwang JS, et al. Metabolism. 2015 Mar;64(3):368-79. doi: 10.1016/j.metabol.2014.11.005. Epub 2014 Nov 20. Metabolism. 2015. PMID: 25516476

Glucosamine attenuates increases of intraabdominal fat, serum leptin levels, and insulin resistance induced by a high-fat diet in rats.

Barrientos C, Racotta R, Quevedo L. Barrientos C, et al. Nutr Res. 2010 Nov;30(11):791-800. doi: 10.1016/j.nutres.2010.10.008. Nutr Res. 2010. PMID: 21130299

Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice.

Tsuchiya K, Sakai H, Suzuki N, Iwashima F, Yoshimoto T, Shichiri M, Hirata Y. Tsuchiya K, et al. Endocrinology. 2007 Oct;148(10):4548-56. doi: 10.1210/en.2006-1371. Epub 2007 Jun 21. Endocrinology. 2007. PMID: 17584959

Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice.

Lee YS, Cha BY, Choi SS, Harada Y, Choi BK, Yonezawa T, Teruya T, Nagai K, Woo JT. Lee YS, et al. Biofactors. 2012 Jul-Aug;38(4):300-8. doi: 10.1002/biof.1022. Epub 2012 Jun 2. Biofactors. 2012. PMID: 22674784

Taurine supplementation prevents morpho-physiological alterations in high-fat diet mice pancreatic β-cells.

Ribeiro RA, Santos-Silva JC, Vettorazzi JF, Cotrim BB, Mobiolli DD, Boschero AC, Carneiro EM. Ribeiro RA, et al. Amino Acids. 2012 Oct;43(4):1791-801. doi: 10.1007/s00726-012-1263-5. Epub 2012 Mar 15. Amino Acids. 2012. PMID: 22418865

Decursin, an active compound isolated from Angelica gigas, inhibits fat accumulation, reduces adipocytokine secretion and improves glucose tolerance in mice fed a high-fat diet.

Hwang JT, Kim SH, Hur HJ, Kim HJ, Park JH, Sung MJ, Yang HJ, Ryu SY, Kim YS, Cha MR, Kim MS, Kwon DY. Hwang JT, et al. Phytother Res. 2012 May;26(5):633-8. doi: 10.1002/ptr.3612. Epub 2011 Oct 4. Phytother Res. 2012. PMID: 21972114

A novel soluble β-1,3-D-glucan salecan reduces adiposity and improves glucose tolerance in high-fat diet-fed mice.

Zhang Y, Xia L, Pang W, Wang T, Chen P, Zhu B, Zhang J. Zhang Y, et al. Br J Nutr. 2013 Jan 28;109(2):254-62. doi: 10.1017/S0007114512000980. Epub 2012 Apr 13. Br J Nutr. 2013. PMID: 22716316

Role of PYK2 in the development of obesity and insulin resistance.

Yu Y, Ross SA, Halseth AE, Hollenbach PW, Hill RJ, Gulve EA, Bond BR. Yu Y, et al. Biochem Biophys Res Commun. 2005 Sep 9;334(4):1085-91. doi: 10.1016/j.bbrc.2005.06.198. Biochem Biophys Res Commun. 2005. PMID: 16039993

Nutrient-adjusted high-fat diet is associated with absence of periepididymal adipose tissue inflammation: is there a link with adequate micronutrient levels?

Yamada M, Maintinguer Norde M, Borges MC, Mieko de Meneses Fujii T, Silva Jacob P, Fonseca-Alaniz MH, Cardoso Alonso-Vale MI, Torres-Leal FL, Tirapegui J, Fock RA, Borelli P, Curi R, Macedo Rogero M. Yamada M, et al. Int J Vitam Nutr Res. 2013;83(5):299-310. doi: 10.1024/0300-9831/a000172. Int J Vitam Nutr Res. 2013. PMID: 25305225

Paraoxonase1 (PON1) reduces insulin resistance in mice fed a high-fat diet, and promotes GLUT4 overexpression in myocytes, via the IRS-1/Akt pathway.

Koren-Gluzer M, Aviram M, Hayek T. Koren-Gluzer M, et al. Atherosclerosis. 2013 Jul;229(1):71-8. doi: 10.1016/j.atherosclerosis.2013.03.028. Epub 2013 Apr 10. Atherosclerosis. 2013. PMID: 23639858

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