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Glucose-lowering with exogenous insulin monotherapy in type 2 diabetes: dose association with all-cause mortality, cardiovascular events and cancer.

Holden SE, Jenkins-Jones S, Morgan CL, Schernthaner G, Currie CJ. Holden SE, et al. Diabetes Obes Metab. 2015 Apr;17(4):350-62. doi: 10.1111/dom.12412. Epub 2014 Dec 10. Diabetes Obes Metab. 2015. PMID: 25399739

Association of insulin dosage with mortality or major adverse cardiovascular events: a retrospective cohort study.

Gamble JM, Chibrikov E, Twells LK, Midodzi WK, Young SW, MacDonald D, Majumdar SR. Gamble JM, et al. Lancet Diabetes Endocrinol. 2017 Jan;5(1):43-52. doi: 10.1016/S2213-8587(16)30316-3. Epub 2016 Nov 17. Lancet Diabetes Endocrinol. 2017. PMID: 27865756

Relationship of glycaemic control and hypoglycaemic episodes to 4-year cardiovascular outcomes in people with type 2 diabetes starting insulin.

Freemantle N, Danchin N, Calvi-Gries F, Vincent M, Home PD. Freemantle N, et al. Diabetes Obes Metab. 2016 Feb;18(2):152-8. doi: 10.1111/dom.12598. Epub 2015 Dec 23. Diabetes Obes Metab. 2016. PMID: 26511332 Free PMC article.

Comparative cardiovascular safety of insulin secretagogues following hospitalization for ischemic heart disease among type 2 diabetes patients: a cohort study.

Huang Y, Abdelmoneim AS, Light P, Qiu W, Simpson SH. Huang Y, et al. J Diabetes Complications. 2015 Mar;29(2):196-202. doi: 10.1016/j.jdiacomp.2014.11.012. Epub 2014 Dec 2. J Diabetes Complications. 2015. PMID: 25534984

Association between Insulin Monotherapy versus Insulin plus Metformin and the Risk of All-Cause Mortality and Other Serious Outcomes: A Retrospective Cohort Study.

Holden SE, Jenkins-Jones S, Currie CJ. Holden SE, et al. PLoS One. 2016 May 6;11(5):e0153594. doi: 10.1371/journal.pone.0153594. eCollection 2016. PLoS One. 2016. PMID: 27152598 Free PMC article.

Dapagliflozin is associated with lower risk of cardiovascular events and all-cause mortality in people with type 2 diabetes (CVD-REAL Nordic) when compared with dipeptidyl peptidase-4 inhibitor therapy: A multinational observational study.

Persson F, Nyström T, Jørgensen ME, Carstensen B, Gulseth HL, Thuresson M, Fenici P, Nathanson D, Eriksson JW, Norhammar A, Bodegard J, Birkeland KI. Persson F, et al. Diabetes Obes Metab. 2018 Feb;20(2):344-351. doi: 10.1111/dom.13077. Epub 2017 Sep 8. Diabetes Obes Metab. 2018. PMID: 28771923 Free PMC article.

No increased risk of cardiovascular events in older adults initiating dipeptidyl peptidase-4 inhibitors vs therapeutic alternatives.

Gokhale M, Buse JB, Jonsson Funk M, Lund J, Pate V, Simpson RJ, Stürmer T. Gokhale M, et al. Diabetes Obes Metab. 2017 Jul;19(7):970-978. doi: 10.1111/dom.12906. Epub 2017 Mar 17. Diabetes Obes Metab. 2017. PMID: 28195389 Free PMC article.

Intensified insulin-based glycaemic control after myocardial infarction: mortality during 20 year follow-up of the randomised Diabetes Mellitus Insulin Glucose Infusion in Acute Myocardial Infarction (DIGAMI 1) trial.

Ritsinger V, Malmberg K, Mårtensson A, Rydén L, Wedel H, Norhammar A. Ritsinger V, et al. Lancet Diabetes Endocrinol. 2014 Aug;2(8):627-33. doi: 10.1016/S2213-8587(14)70088-9. Epub 2014 May 13. Lancet Diabetes Endocrinol. 2014. PMID: 24831989 Clinical Trial.

Fasting and post-prandial glucose and diabetic complication. A meta-analysis.

Monami M, Adalsteinsson JE, Desideri CM, Ragghianti B, Dicembrini I, Mannucci E. Monami M, et al. Nutr Metab Cardiovasc Dis. 2013 Jul;23(7):591-8. doi: 10.1016/j.numecd.2013.03.007. Epub 2013 May 24. Nutr Metab Cardiovasc Dis. 2013. PMID: 23711419

Efficacy and Cardiovascular Safety of Linagliptin as an Add-On to Insulin in Type 2 Diabetes: A Pooled Comprehensive Post Hoc Analysis.

Zinman B, Ahrén B, Neubacher D, Patel S, Woerle HJ, Johansen OE. Zinman B, et al. Can J Diabetes. 2016 Feb;40(1):50-7. doi: 10.1016/j.jcjd.2015.06.010. Epub 2015 Oct 21. Can J Diabetes. 2016. PMID: 26474870 Clinical Trial.

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