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25242669,26349474,24768581,24018023,24780111,24309368,25903122,29402243,23581415,25704955,24636848,22333554,24715074,26508839,25617986,28822888,24222153,26341687,21784628,22161771,18458038,23489557,26911310,26238424,24663503,28213001,17610986,27506489,24685306,26169499,25873045,27619632,24412619,27821111,20195171,23783797,24997732,25669832,26493267,27040855,25422153,28623122,27999211,29382302,25261231,22677429,23540718,23910906,25616723,21550561,28258422,22760226,21802939,23911281,26187428,26092590,25611026,22993320,25175099,24222150,22215752,22000696,18176089,24192511,25263853,21216488,23079155,25611025,25503781,26768483,28639751,27655708,17409801,29655198,25454007,31699150,30950859,21964534,18520300,30107372,18379359,26859739,27710972,26308162,26148607,26993607,26315967,27755796,26624882,27565910,28742280,25976428,30268482,28776311,22425916,28126915,26980062,24977454,25731731,34034713,22483783,26364032,28712979,29477365,34577852,25854383,27669169,27875527,34259953,31564835,26867973,33331920,26313661,32144133,22174092,27637087,27212579,26089022,26117231,24636847,29199672,31892337,28777825,29101033,26725853,26237501,25700389,24338271,24118906,25246385,28271729,21482992,24086949,21194487,30343004,26248464,27978873,21777761,26845114,29212495,25417728,27495021,30587399,26799287,28396313,28739703,26260811,19088154,25637458,25964523,21777763,29563137,29266865,29995771,33780662,34332557,26474174,25203821,28577939,26524539,25784657,35305259,28955007,28237165,30156984,25242667,28219201,29579334,28743421,34730203,26829230,30451714,36333268,31918452,30268476,25800570,30139222,15952926,32408134,35305596,28731495,23079575,27468867,34208765,25676720,21366910,26124345,29902802,24878189,26331821,24970910,29174086,32916310,34032715,28901317,25104233,28065465,27780855,37105304,27978872,34733631,25058005,25806348,33589450,21304034,26070531,27040849,17409937,31356117,36259253,26227959,20871269,24113003,27764781,26076815,30061586,35728482,26206728,25676406,34168988,27213587,26089726,27603946,25399974,29761660,30266586,33522139,35109665,28840704,18172786,25145405,28592399,33652831,23985030,35248841,26408304,29483958,29121501,22771314,31179076,24922692,26391764,36064984,33928022,18078086,27033062,19887865,36002368,26816540,31557965,34548309,34970481,35094066,32382334,28454414,26207209,27036494,29707288,33193830,31656643,25610713,27382309,29936470,12534150,28829811,34688250,31333456,35306915,34818973,29621875,26168678,29718881,33606592,26125777,29285237,26628299,36556319,33440959,26557904,25806150,28920271,29515002,27666550,32508029,26958497,31205913,25784483,23691453,34926253,28819384,16857824,25990950,28424775,26798589,33511076,29100434,26629427,33138052,32615813,32907839,28685062,29029530,34249697,35117191,33804721,32565965,34589984,27123299,33952497,28920234,36791768,27807951,26958501,31285870,32236267,30661185,28490925,29340055,27825546,25232221,37074454,31167592,30719148,36994198,27385984,31602263,34120312,26273378,31857948,25538894,35733510,35505288,34359788,30719215,29726094,31404289,35571024,31737494,30232957,36788891,36765600,28210134,29018574,33186889,29319030,35463301,29254184,34796106,28790845,36010982,29435131,23991294,35465042,35756605,30559979,30562682,28280362,36910653,35949840,33209632,26508917,22970367,27197235,24348052,26893752,33613698,25806236,31266248,25563355,28003764,28915692,36438852,30022837,31572008,34733613,27197234,27790122,34267282,24649264,33841940,36644180,25866224,25967686,27330954,29399169,35903205,35770234,33898315,35280312,31555524,32606781,29088904,29075127,22754591,32076486,35068940,29492192,30108437,33520716,31336878,35252898,27566188,23251095,33850890,31936895,28520590,34093743,35159099,23420122,31728434,36442902,36879350,26379824,31417660,25806266,21789118,31579626,30498734,32256580,34069851,28111612,34322390,36875303,36313723,33425564,32642093,34567259,33282740,24628403,35444951,34630120,24252457,25806282,34881026,34680416,29484139,35530645,25810955,34504595,36435452,35207417,37152062,25806267,37143400,32992872,35251994,34441254,28978016,35646640,36339256,26491352,34201833,24976979,33863983,26933421,33776477,35425698,35223530,30643552,23172990,32523650,34164204,32670872,28947971,36505304,33869038,23082072,35116516,25562202,31083571,29217691,34622931,26483606,27202623,26609689,30405851,27610045,27284438,36934893,31547471,36915597,30174925,25788863,35116975,36519014,30705845,35362056,27652201,27202154,30429129,32038914,29780711,35094086,25806321,28567396,35399242,23205294,32694876,29708166,20630074,37077198,25806185,35309801,29147431,29452410[uid]

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Results by year

Year	Number of Results
2002	1
2005	1
2006	2
2007	4
2008	6
2009	3
2010	3
2011	11
2012	26
2013	28
2014	43
2015	71
2016	61
2017	63
2018	50
2019	39
2020	28
2021	55
2022	44
2023	21
2024	0

505 results

Page of 51

Results by year

Page 1

Rationale and study design of the IRENE-trial (NVALT-16): a phase II trial to evaluate iressa rechallenge in advanced NSCLC patients with an activating EGFR mutation who responded to an EGFR-TKI used as first-line or previous treatment.

Kuiper JL, Heideman DA, Würdinger T, Grünberg K, Groen HJ, Smit EF. Kuiper JL, et al. Clin Lung Cancer. 2015 Jan;16(1):60-6. doi: 10.1016/j.cllc.2014.07.008. Epub 2014 Aug 15. Clin Lung Cancer. 2015. PMID: 25242669 Clinical Trial.

EGFR-TKI rechallenge with bevacizumab in EGFR-mutant non-small cell lung cancer.

Otsuka K, Hata A, Takeshita J, Okuda C, Kaji R, Masago K, Fujita S, Katakami N. Otsuka K, et al. Cancer Chemother Pharmacol. 2015 Oct;76(4):835-41. doi: 10.1007/s00280-015-2867-8. Epub 2015 Sep 8. Cancer Chemother Pharmacol. 2015. PMID: 26349474

Incidence of T790M mutation in (sequential) rebiopsies in EGFR-mutated NSCLC-patients.

Kuiper JL, Heideman DA, Thunnissen E, Paul MA, van Wijk AW, Postmus PE, Smit EF. Kuiper JL, et al. Lung Cancer. 2014 Jul;85(1):19-24. doi: 10.1016/j.lungcan.2014.03.016. Epub 2014 Mar 23. Lung Cancer. 2014. PMID: 24768581

A retrospective analysis of 335 Japanese lung cancer patients who responded to initial gefitinib treatment.

Nishino K, Imamura F, Morita S, Mori M, Komuta K, Kijima T, Namba Y, Kumagai T, Yamamoto S, Tachibana I, Nakazawa Y, Uchida J, Minami S, Takahashi R, Yano Y, Okuyama T, Kumanogoh A. Nishino K, et al. Lung Cancer. 2013 Nov;82(2):299-304. doi: 10.1016/j.lungcan.2013.08.009. Epub 2013 Aug 21. Lung Cancer. 2013. PMID: 24018023

Efficacy of epidermal growth factor receptor inhibitors versus chemotherapy as second-line treatment in advanced non-small-cell lung cancer with wild-type EGFR: a meta-analysis of randomized controlled clinical trials.

Zhao N, Zhang XC, Yan HH, Yang JJ, Wu YL. Zhao N, et al. Lung Cancer. 2014 Jul;85(1):66-73. doi: 10.1016/j.lungcan.2014.03.026. Epub 2014 Apr 13. Lung Cancer. 2014. PMID: 24780111

Clinical characteristics of non-small cell lung cancer patients who experienced acquired resistance during gefitinib treatment.

Kim HR, Lee JC, Kim YC, Kim KS, Oh IJ, Lee SY, Jang TW, Lee MK, Shin KC, Lee GH, Ryu JS, Jang SH, Son JW, Lee JE, Kim SY, Kim HJ, Lee KY. Kim HR, et al. Lung Cancer. 2014 Feb;83(2):252-8. doi: 10.1016/j.lungcan.2013.11.008. Epub 2013 Nov 20. Lung Cancer. 2014. PMID: 24309368

A phase II trial of gefitinib monotherapy in pretreated patients with advanced non-small cell lung cancer not harboring activating EGFR mutations: implications of sensitive EGFR mutation test.

Choi MK, Hong JY, Chang WJ, Kim MJ, Kim SM, Jung HA, Do IG, Choi YL, Sun JM, Ahn JS, Park K, Ahn MJ. Choi MK, et al. Cancer Chemother Pharmacol. 2015 Jun;75(6):1229-36. doi: 10.1007/s00280-015-2740-9. Epub 2015 Apr 23. Cancer Chemother Pharmacol. 2015. PMID: 25903122 Clinical Trial.

Treatment decisions, clinical outcomes, and pharmacoeconomics in the treatment of patients with EGFR mutated stage III/IV NSCLC in Germany: an observational study.

Schuette W, Schirmacher P, Eberhardt WEE, Dietel M, Zirrgiebel U, Muehlenhoff L, Thomas M. Schuette W, et al. BMC Cancer. 2018 Feb 5;18(1):135. doi: 10.1186/s12885-018-4032-3. BMC Cancer. 2018. PMID: 29402243 Free PMC article. Clinical Trial.

Comparison of EGFR-TKI and chemotherapy in the first-line treatment of advanced EGFR mutation-positive NSCLC.

Fiala O, Pesek M, Finek J, Benesova L, Bortlicek Z, Minarik M. Fiala O, et al. Neoplasma. 2013;60(4):425-31. doi: 10.4149/neo_2013_055. Neoplasma. 2013. PMID: 23581415

Chronic nicotine exposure mediates resistance to EGFR-TKI in EGFR-mutated lung cancer via an EGFR signal.

Togashi Y, Hayashi H, Okamoto K, Fumita S, Terashima M, de Velasco MA, Sakai K, Fujita Y, Tomida S, Nakagawa K, Nishio K. Togashi Y, et al. Lung Cancer. 2015 Apr;88(1):16-23. doi: 10.1016/j.lungcan.2015.01.027. Epub 2015 Feb 7. Lung Cancer. 2015. PMID: 25704955

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505 results

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