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Results: 1 to 20 of 98

1.

Human structural proteome-wide characterization of Cyclosporine A targets.

Hu G, Wang K, Groedendyk J, Barakat K, Mizianty MJ, Ruan J, Michalak M, Kurgan L.

Bioinformatics. 2014 Aug 28. pii: btu581. [Epub ahead of print]

PMID:
25172926
[PubMed - as supplied by publisher]
2.

Prediction and analysis of nucleotide-binding residues using sequence and sequence-derived structural descriptors.

Chen K, Mizianty MJ, Kurgan L.

Bioinformatics. 2012 Feb 1;28(3):331-41. doi: 10.1093/bioinformatics/btr657. Epub 2011 Nov 29.

PMID:
22130595
[PubMed - indexed for MEDLINE]
Free Article
3.

Regulation of MAPK signaling pathways through immunophilin-ligand complex.

Matsuda S, Koyasu S.

Curr Top Med Chem. 2003;3(12):1358-67. Review.

PMID:
12871167
[PubMed - indexed for MEDLINE]
4.

A comparison of cyclosporine binding by cyclophilin and calmodulin and the identification of a novel 45 KD cyclosporine-binding phosphoprotein in Jurkat cells.

Foxwell BM, Hiestand PC, Wenger R, Ryffel B.

Transplantation. 1988 Aug;46(2 Suppl):35S-40S.

PMID:
3043797
[PubMed - indexed for MEDLINE]
5.

KAP degradation by calpain is associated with CK2 phosphorylation and provides a novel mechanism for cyclosporine A-induced proximal tubule injury.

Tornavaca O, Sarró E, Pascual G, Bardaji B, Montero MA, Salcedo MT, Plana M, López-Hellin J, Itarte E, Meseguer A.

PLoS One. 2011;6(9):e25746. doi: 10.1371/journal.pone.0025746. Epub 2011 Sep 28.

PMID:
21980535
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability.

Yau WL, Blisnick T, Taly JF, Helmer-Citterich M, Schiene-Fischer C, Leclercq O, Li J, Schmidt-Arras D, Morales MA, Notredame C, Romo D, Bastin P, Späth GF.

PLoS Negl Trop Dis. 2010 Jun 29;4(6):e729. doi: 10.1371/journal.pntd.0000729.

PMID:
20614016
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Cyclosporin A induces apoptosis in H9c2 cardiomyoblast cells through calcium-sensing receptor-mediated activation of the ERK MAPK and p38 MAPK pathways.

Chi J, Zhu Y, Fu Y, Liu Y, Zhang X, Han L, Yin X, Zhao D.

Mol Cell Biochem. 2012 Aug;367(1-2):227-36. doi: 10.1007/s11010-012-1336-5. Epub 2012 Jun 8.

PMID:
22678567
[PubMed - indexed for MEDLINE]
8.

Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements.

West GM, Tucker CL, Xu T, Park SK, Han X, Yates JR 3rd, Fitzgerald MC.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9078-82. doi: 10.1073/pnas.1000148107. Epub 2010 May 3.

PMID:
20439767
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Effect of cyclosporin A and analogues on cytosolic calcium and vasoconstriction: possible lack of relationship to immunosuppressive activity.

Lo Russo A, Passaquin AC, André P, Skutella M, Rüegg UT.

Br J Pharmacol. 1996 Jun;118(4):885-92.

PMID:
8799558
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Controlling programmed cell death with a cyclophilin-cyclosporin-based chemical inducer of dimerization.

Belshaw PJ, Spencer DM, Crabtree GR, Schreiber SL.

Chem Biol. 1996 Sep;3(9):731-8.

PMID:
8939689
[PubMed - indexed for MEDLINE]
11.

Drug discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitors.

Xie L, Li J, Xie L, Bourne PE.

PLoS Comput Biol. 2009 May;5(5):e1000387. doi: 10.1371/journal.pcbi.1000387. Epub 2009 May 15.

PMID:
19436720
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A.

Cardenas ME, Muir RS, Breuder T, Heitman J.

EMBO J. 1995 Jun 15;14(12):2772-83.

PMID:
7540976
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A large-scale computational approach to drug repositioning.

Li YY, An J, Jones SJ.

Genome Inform. 2006;17(2):239-47.

PMID:
17503396
[PubMed - indexed for MEDLINE]
14.

Editorial: protein systems biology: method, regulation, and network.

Chen Q, Chen M.

Curr Protein Pept Sci. 2014;15(6):519-21.

PMID:
25135673
[PubMed - in process]
15.

Mechanism of cyclosporine-induced overgrowth in gingiva.

Chae HJ, Ha MS, Yun DH, Pae HO, Chung HT, Chae SW, Jung YK, Kim HR.

J Dent Res. 2006 Jun;85(6):515-9.

PMID:
16723647
[PubMed - indexed for MEDLINE]
16.

1H, 13C and 15N backbone assignments of cyclophilin when bound to cyclosporin A (CsA) and preliminary structural characterization of the CsA binding site.

Neri P, Meadows R, Gemmecker G, Olejniczak E, Nettesheim D, Logan T, Simmer R, Helfrich R, Holzman T, Severin J, et al.

FEBS Lett. 1991 Dec 2;294(1-2):81-8.

PMID:
1743298
[PubMed - indexed for MEDLINE]
17.

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex.

Pflügl G, Kallen J, Schirmer T, Jansonius JN, Zurini MG, Walkinshaw MD.

Nature. 1993 Jan 7;361(6407):91-4.

PMID:
8421501
[PubMed - indexed for MEDLINE]
18.

Sympathetic neural mechanisms of cyclosporine-induced hypertension.

Sander M, Lyson T, Thomas GD, Victor RG.

Am J Hypertens. 1996 Nov;9(11):121S-138S. Review.

PMID:
8931845
[PubMed - indexed for MEDLINE]
19.

Expression of apoptosis-related genes in chronic cyclosporine nephrotoxicity in mice.

Yang CW, Faulkner GR, Wahba IM, Christianson TA, Bagby GC, Jin DC, Abboud HE, Andoh TF, Bennett WM.

Am J Transplant. 2002 May;2(5):391-9.

PMID:
12123203
[PubMed - indexed for MEDLINE]
Free Article
20.

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity.

Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL.

Biochemistry. 1992 Apr 28;31(16):3896-901.

PMID:
1373650
[PubMed - indexed for MEDLINE]

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