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Unmethylation of the CHRNB4 gene is an unfavorable prognostic factor in non-small cell lung cancer.

Yoo SS, Lee SM, Do SK, Lee WK, Kim DS, Park JY.

Lung Cancer. 2014 Oct;86(1):85-90. doi: 10.1016/j.lungcan.2014.08.002. Epub 2014 Aug 12.


Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.

Scherf DB, Sarkisyan N, Jacobsson H, Claus R, Bermejo JL, Peil B, Gu L, Muley T, Meister M, Dienemann H, Plass C, Risch A.

Oncogene. 2013 Jul 11;32(28):3329-38. doi: 10.1038/onc.2012.344. Epub 2012 Sep 3.


Identification of the methylation of p14ARF promoter as a novel non-invasive biomarker for early detection of lung cancer.

Li L, Shen Y, Wang M, Tang D, Luo Y, Jiao W, Wang Z, Yang R, Tian K.

Clin Transl Oncol. 2014 Jun;16(6):581-9. doi: 10.1007/s12094-013-1122-1. Epub 2013 Oct 24.


Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers.

Lam DC, Girard L, Ramirez R, Chau WS, Suen WS, Sheridan S, Tin VP, Chung LP, Wong MP, Shay JW, Gazdar AF, Lam WK, Minna JD.

Cancer Res. 2007 May 15;67(10):4638-47.


Glutathione S-transferase PI (GST-PI) mRNA expression and DNA methylation is involved in the pathogenesis and prognosis of NSCLC.

Grimminger PP, Maus MK, Schneider PM, Metzger R, Hölscher AH, Sugita H, Danenberg PV, Alakus H, Brabender J.

Lung Cancer. 2012 Oct;78(1):87-91. doi: 10.1016/j.lungcan.2012.07.008. Epub 2012 Aug 11.


TFPI-2 methylation predicts poor prognosis in non-small cell lung cancer.

Wu D, Xiong L, Wu S, Jiang M, Lian G, Wang M.

Lung Cancer. 2012 Apr;76(1):106-11. doi: 10.1016/j.lungcan.2011.09.005. Epub 2011 Oct 7.


Can aberrant promoter hypermethylation of CpG islands predict the clinical outcome of non-small cell lung cancer after curative resection?

Kim YT, Lee SH, Sung SW, Kim JH.

Ann Thorac Surg. 2005 Apr;79(4):1180-8; discussion 1180-8.


Methylation markers of early-stage non-small cell lung cancer.

Lokk K, Vooder T, Kolde R, Välk K, Võsa U, Roosipuu R, Milani L, Fischer K, Koltsina M, Urgard E, Annilo T, Metspalu A, Tõnisson N.

PLoS One. 2012;7(6):e39813. doi: 10.1371/journal.pone.0039813. Epub 2012 Jun 29.


Aberrant methylation of the FHIT gene in chronic smokers with early stage squamous cell carcinoma of the lung.

Kim JS, Kim H, Shim YM, Han J, Park J, Kim DH.

Carcinogenesis. 2004 Nov;25(11):2165-71. Epub 2004 Jul 1.


A functional polymorphism on chromosome 15q25 associated with survival of early stage non-small-cell lung cancer.

Jin G, Bae EY, Yang E, Lee EB, Lee WK, Choi JE, Jeon HS, Yoo SS, Lee SY, Lee J, Cha SI, Kim CH, Cho S, Jheon S, Park JY.

J Thorac Oncol. 2012 May;7(5):808-14. doi: 10.1097/JTO.0b013e31824c7d7c.


A prognostic DNA methylation signature for stage I non-small-cell lung cancer.

Sandoval J, Mendez-Gonzalez J, Nadal E, Chen G, Carmona FJ, Sayols S, Moran S, Heyn H, Vizoso M, Gomez A, Sanchez-Cespedes M, Assenov Y, Müller F, Bock C, Taron M, Mora J, Muscarella LA, Liloglou T, Davies M, Pollan M, Pajares MJ, Torre W, Montuenga LM, Brambilla E, Field JK, Roz L, Lo Iacono M, Scagliotti GV, Rosell R, Beer DG, Esteller M.

J Clin Oncol. 2013 Nov 10;31(32):4140-7. doi: 10.1200/JCO.2012.48.5516. Epub 2013 Sep 30.


Epigenetic inactivation of checkpoint kinase 2 gene in non-small cell lung cancer and its relationship with clinicopathological features.

Kim DS, Kim MJ, Lee JY, Lee SM, Choi JE, Lee SY, Park JY.

Lung Cancer. 2009 Aug;65(2):247-50. doi: 10.1016/j.lungcan.2009.03.011. Epub 2009 Apr 11.


p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer.

Kim DH, Nelson HH, Wiencke JK, Zheng S, Christiani DC, Wain JC, Mark EJ, Kelsey KT.

Cancer Res. 2001 Apr 15;61(8):3419-24.


Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival.

Brabender J, Usadel H, Danenberg KD, Metzger R, Schneider PM, Lord RV, Wickramasinghe K, Lum CE, Park J, Salonga D, Singer J, Sidransky D, Hölscher AH, Meltzer SJ, Danenberg PV.

Oncogene. 2001 Jun 14;20(27):3528-32.


Genome-wide CpG island methylation analyses in non-small cell lung cancer patients.

Heller G, Babinsky VN, Ziegler B, Weinzierl M, Noll C, Altenberger C, Müllauer L, Dekan G, Grin Y, Lang G, End-Pfützenreuter A, Steiner I, Zehetmayer S, Döme B, Arns BM, Fong KM, Wright CM, Yang IA, Klepetko W, Posch M, Zielinski CC, Zöchbauer-Müller S.

Carcinogenesis. 2013 Mar;34(3):513-21. doi: 10.1093/carcin/bgs363. Epub 2012 Nov 19.


Nicotine activates cell-signaling pathways through muscle-type and neuronal nicotinic acetylcholine receptors in non-small cell lung cancer cells.

Carlisle DL, Liu X, Hopkins TM, Swick MC, Dhir R, Siegfried JM.

Pulm Pharmacol Ther. 2007;20(6):629-41. Epub 2006 Aug 18.


Role of alpha7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation.

Paleari L, Catassi A, Ciarlo M, Cavalieri Z, Bruzzo C, Servent D, Cesario A, Chessa L, Cilli M, Piccardi F, Granone P, Russo P.

Cell Prolif. 2008 Dec;41(6):936-59. doi: 10.1111/j.1365-2184.2008.00566.x. Erratum in: Cell Prolif. 2009 Feb;42(1):122. Cell Prolif. 2009 Aug;42(4):568.


Epigenetic inactivation of Homeobox A5 gene in nonsmall cell lung cancer and its relationship with clinicopathological features.

Kim DS, Kim MJ, Lee JY, Lee SM, Choi JY, Yoon GS, Na YK, Hong HS, Kim SG, Choi JE, Lee SY, Park JY.

Mol Carcinog. 2009 Dec;48(12):1109-15. doi: 10.1002/mc.20561.


Association of methylation of the RAR-β gene with cigarette smoking in non-small cell lung cancer with Southern-Central Chinese population.

Li W, Deng J, Wang SS, Ma L, Pei J, Zeng XX, Tang JX.

Asian Pac J Cancer Prev. 2014;15(24):10937-41.

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