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Results: 1 to 20 of 97

1.

Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases.

Lim JL, Wilhelmus MM, de Vries HE, Drukarch B, Hoozemans JJ, van Horssen J.

Arch Toxicol. 2014 Oct;88(10):1773-86. doi: 10.1007/s00204-014-1338-z. Epub 2014 Aug 28.

PMID:
25164826
[PubMed - in process]
2.

Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

de Vries HE, Witte M, Hondius D, Rozemuller AJ, Drukarch B, Hoozemans J, van Horssen J.

Free Radic Biol Med. 2008 Nov 15;45(10):1375-83. doi: 10.1016/j.freeradbiomed.2008.09.001. Epub 2008 Sep 13. Review.

PMID:
18824091
[PubMed - indexed for MEDLINE]
3.

Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia.

Calabrese V, Lodi R, Tonon C, D'Agata V, Sapienza M, Scapagnini G, Mangiameli A, Pennisi G, Stella AM, Butterfield DA.

J Neurol Sci. 2005 Jun 15;233(1-2):145-62. Review.

PMID:
15896810
[PubMed - indexed for MEDLINE]
4.

The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease.

Tufekci KU, Civi Bayin E, Genc S, Genc K.

Parkinsons Dis. 2011 Feb 22;2011:314082. doi: 10.4061/2011/314082.

PMID:
21403858
[PubMed]
Free PMC Article
5.

Therapeutic approach to neurodegenerative diseases by medical gases: focusing on redox signaling and related antioxidant enzymes.

Fujita K, Yamafuji M, Nakabeppu Y, Noda M.

Oxid Med Cell Longev. 2012;2012:324256. doi: 10.1155/2012/324256. Epub 2012 Jul 1. Review.

PMID:
22811764
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Reprint of: Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.

Satoh T, McKercher SR, Lipton SA.

Free Radic Biol Med. 2014 Jan;66:45-57. doi: 10.1016/j.freeradbiomed.2013.11.002. Epub 2013 Nov 18.

PMID:
24262357
[PubMed]
7.

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.

Satoh T, McKercher SR, Lipton SA.

Free Radic Biol Med. 2013 Dec;65:645-57. doi: 10.1016/j.freeradbiomed.2013.07.022. Epub 2013 Jul 25.

PMID:
23892355
[PubMed - in process]
8.

The Nrf2-ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders.

van Muiswinkel FL, Kuiperij HB.

Curr Drug Targets CNS Neurol Disord. 2005 Jun;4(3):267-81. Review.

PMID:
15975029
[PubMed - indexed for MEDLINE]
9.

Regulation of the Nrf2 antioxidant pathway by microRNAs: New players in micromanaging redox homeostasis.

Cheng X, Ku CH, Siow RC.

Free Radic Biol Med. 2013 Sep;64:4-11. doi: 10.1016/j.freeradbiomed.2013.07.025. Epub 2013 Jul 21. Review.

PMID:
23880293
[PubMed - indexed for MEDLINE]
10.

Nrf2/ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS.

Petri S, K├Ârner S, Kiaei M.

Neurol Res Int. 2012;2012:878030. doi: 10.1155/2012/878030. Epub 2012 Sep 20.

PMID:
23050144
[PubMed]
Free PMC Article
11.

Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology.

Schreibelt G, van Horssen J, van Rossum S, Dijkstra CD, Drukarch B, de Vries HE.

Brain Res Rev. 2007 Dec;56(2):322-30. Epub 2007 Jul 27. Review.

PMID:
17761296
[PubMed - indexed for MEDLINE]
12.

Radical changes in multiple sclerosis pathogenesis.

van Horssen J, Witte ME, Schreibelt G, de Vries HE.

Biochim Biophys Acta. 2011 Feb;1812(2):141-50. doi: 10.1016/j.bbadis.2010.06.011. Epub 2010 Jun 27. Review.

PMID:
20600869
[PubMed - indexed for MEDLINE]
Free Article
13.

Nuclear factor erythroid 2-related factor 2 signaling in Parkinson disease: a promising multi therapeutic target against oxidative stress, neuroinflammation and cell death.

Kumar H, Koppula S, Kim IS, More SV, Kim BW, Choi DK.

CNS Neurol Disord Drug Targets. 2012 Dec;11(8):1015-29. Review.

PMID:
23244425
[PubMed - indexed for MEDLINE]
14.

SOD1 and DJ-1 converge at Nrf2 pathway: a clue for antioxidant therapeutic potential in neurodegeneration.

Milani P, Ambrosi G, Gammoh O, Blandini F, Cereda C.

Oxid Med Cell Longev. 2013;2013:836760. doi: 10.1155/2013/836760. Epub 2013 Jul 28. Review.

PMID:
23983902
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mitochondrial diseases of the brain.

Chaturvedi RK, Flint Beal M.

Free Radic Biol Med. 2013 Oct;63:1-29. doi: 10.1016/j.freeradbiomed.2013.03.018. Epub 2013 Apr 6. Review.

PMID:
23567191
[PubMed - indexed for MEDLINE]
16.

Mechanisms of Oxidative Damage in Multiple Sclerosis and Neurodegenerative Diseases: Therapeutic Modulation via Fumaric Acid Esters.

Lee DH, Gold R, Linker RA.

Int J Mol Sci. 2012;13(9):11783-803. doi: 10.3390/ijms130911783. Epub 2012 Sep 18.

PMID:
23109883
[PubMed]
Free PMC Article
17.

Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like ECH-associated protein 1 defense pathway.

Cheng X, Siow RC, Mann GE.

Antioxid Redox Signal. 2011 Feb 1;14(3):469-87. doi: 10.1089/ars.2010.3283. Epub 2010 Aug 20. Review.

PMID:
20524845
[PubMed - indexed for MEDLINE]
18.

Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.

Yang L, Calingasan NY, Thomas B, Chaturvedi RK, Kiaei M, Wille EJ, Liby KT, Williams C, Royce D, Risingsong R, Musiek ES, Morrow JD, Sporn M, Beal MF.

PLoS One. 2009 Jun 1;4(6):e5757. doi: 10.1371/journal.pone.0005757.

PMID:
19484125
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes.

Calabrese V, Boyd-Kimball D, Scapagnini G, Butterfield DA.

In Vivo. 2004 May-Jun;18(3):245-67. Review.

PMID:
15341181
[PubMed - indexed for MEDLINE]
Free Article
20.

Mitochondria, oxidative stress and neurodegeneration.

Federico A, Cardaioli E, Da Pozzo P, Formichi P, Gallus GN, Radi E.

J Neurol Sci. 2012 Nov 15;322(1-2):254-62. doi: 10.1016/j.jns.2012.05.030. Epub 2012 Jun 4. Review.

PMID:
22669122
[PubMed - indexed for MEDLINE]

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