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An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines.

Vencken SF, Sethupathy P, Blackshields G, Spillane C, Elbaruni S, Sheils O, Gallagher MF, O'Leary JJ.

BMC Genomics. 2014 Aug 25;15:711. doi: 10.1186/1471-2164-15-711.


Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?

Gunaratne PH.

Curr Stem Cell Res Ther. 2009 Sep;4(3):168-77. Review.


SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.

Boumahdi S, Driessens G, Lapouge G, Rorive S, Nassar D, Le Mercier M, Delatte B, Caauwe A, Lenglez S, Nkusi E, Brohée S, Salmon I, Dubois C, del Marmol V, Fuks F, Beck B, Blanpain C.

Nature. 2014 Jul 10;511(7508):246-50. doi: 10.1038/nature13305. Epub 2014 Jun 8.


Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells.

Yu HB, Kunarso G, Hong FH, Stanton LW.

J Biol Chem. 2009 Nov 6;284(45):31327-35. doi: 10.1074/jbc.M109.016162. Epub 2009 Sep 9.


A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells.

Jung M, Peterson H, Chavez L, Kahlem P, Lehrach H, Vilo J, Adjaye J.

PLoS One. 2010 May 21;5(5):e10709. doi: 10.1371/journal.pone.0010709.


Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells.

Adachi K, Nikaido I, Ohta H, Ohtsuka S, Ura H, Kadota M, Wakayama T, Ueda HR, Niwa H.

Mol Cell. 2013 Nov 7;52(3):380-92. doi: 10.1016/j.molcel.2013.09.002. Epub 2013 Oct 10.


The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2).

Sussman RT, Stanek TJ, Esteso P, Gearhart JD, Knudsen KE, McMahon SB.

J Biol Chem. 2013 Aug 16;288(33):24234-46. doi: 10.1074/jbc.M113.469783. Epub 2013 Jun 12.


MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis.

Otsubo T, Akiyama Y, Hashimoto Y, Shimada S, Goto K, Yuasa Y.

PLoS One. 2011 Jan 27;6(1):e16617. doi: 10.1371/journal.pone.0016617.


Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal.

Wang Y, Xu Z, Jiang J, Xu C, Kang J, Xiao L, Wu M, Xiong J, Guo X, Liu H.

Dev Cell. 2013 Apr 15;25(1):69-80. doi: 10.1016/j.devcel.2013.03.002. Epub 2013 Mar 28.


Sex-determining region Y-box 2 and GA-binding proteins regulate the transcription of liver receptor homolog-1 in early embryonic cells.

Kanno M, Yazawa T, Kawabe S, Imamichi Y, Usami Y, Ju Y, Matsumura T, Mizutani T, Fujieda S, Miyamoto K.

Biochim Biophys Acta. 2014 May;1839(5):406-14. doi: 10.1016/j.bbagrm.2014.03.016. Epub 2014 Apr 3.


Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate.

Mallanna SK, Ormsbee BD, Iacovino M, Gilmore JM, Cox JL, Kyba M, Washburn MP, Rizzino A.

Stem Cells. 2010 Oct;28(10):1715-27. doi: 10.1002/stem.494.


Predicting distinct organization of transcription factor binding sites on the promoter regions: a new genome-based approach to expand human embryonic stem cell regulatory network.

Hosseinpour B, Bakhtiarizadeh MR, Khosravi P, Ebrahimie E.

Gene. 2013 Dec 1;531(2):212-9. doi: 10.1016/j.gene.2013.09.011. Epub 2013 Sep 13.


MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells.

Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS.

Cell. 2009 May 15;137(4):647-58. doi: 10.1016/j.cell.2009.02.038. Epub 2009 Apr 30.


In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach.

Chavez L, Bais AS, Vingron M, Lehrach H, Adjaye J, Herwig R.

BMC Genomics. 2009 Jul 15;10:314. doi: 10.1186/1471-2164-10-314.


Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter.

Barroso-delJesus A, Romero-López C, Lucena-Aguilar G, Melen GJ, Sanchez L, Ligero G, Berzal-Herranz A, Menendez P.

Mol Cell Biol. 2008 Nov;28(21):6609-19. doi: 10.1128/MCB.00398-08. Epub 2008 Aug 25.


The multiple roles for Sox2 in stem cell maintenance and tumorigenesis.

Liu K, Lin B, Zhao M, Yang X, Chen M, Gao A, Liu F, Que J, Lan X.

Cell Signal. 2013 May;25(5):1264-71. doi: 10.1016/j.cellsig.2013.02.013. Epub 2013 Feb 15. Review.


Cervical cancer cells with positive Sox2 expression exhibit the properties of cancer stem cells.

Liu XF, Yang WT, Xu R, Liu JT, Zheng PS.

PLoS One. 2014 Jan 28;9(1):e87092. doi: 10.1371/journal.pone.0087092. eCollection 2014.

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