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Results: 1 to 20 of 96

1.

Site-specific modification of the anticancer and antituberculosis polyether salinomycin by biosynthetic engineering.

Luhavaya H, Williams SR, Hong H, Gonzaga de Oliveira L, Leadlay PF.

Chembiochem. 2014 Sep 22;15(14):2081-5. doi: 10.1002/cbic.201402300. Epub 2014 Aug 22.

PMID:
25155178
[PubMed - in process]
2.

Cloning and characterization of the polyether salinomycin biosynthesis gene cluster of Streptomyces albus XM211.

Jiang C, Wang H, Kang Q, Liu J, Bai L.

Appl Environ Microbiol. 2012 Feb;78(4):994-1003. doi: 10.1128/AEM.06701-11. Epub 2011 Dec 9.

PMID:
22156425
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Radical oxidative cyclization of spiroacetals to bis-spiroacetals: an overview.

Brimble MA.

Molecules. 2004 May 31;9(6):394-404.

PMID:
18007440
[PubMed - indexed for MEDLINE]
Free Article
4.

Salinomycin in cancer: A new mission for an old agent.

Naujokat C, Fuchs D, Opelz G.

Mol Med Rep. 2010 Jul-Aug;3(4):555-9. doi: 10.3892/mmr_00000296.

PMID:
21472278
[PubMed]
5.

Semisynthesis of SY-1 for investigation of breast cancer stem cell selectivity of C-ring-modified salinomycin analogues.

Huang X, Borgström B, Månsson L, Persson L, Oredsson S, Hegardt C, Strand D.

ACS Chem Biol. 2014 Jul 18;9(7):1587-94. doi: 10.1021/cb5002153. Epub 2014 May 29.

PMID:
24841425
[PubMed - in process]
6.

Genetic screening strategy for rapid access to polyether ionophore producers and products in actinomycetes.

Wang H, Liu N, Xi L, Rong X, Ruan J, Huang Y.

Appl Environ Microbiol. 2011 May;77(10):3433-42. doi: 10.1128/AEM.02915-10. Epub 2011 Mar 18.

PMID:
21421776
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Polyether ionophores-promising bioactive molecules for cancer therapy.

Huczyński A.

Bioorg Med Chem Lett. 2012 Dec 1;22(23):7002-10. doi: 10.1016/j.bmcl.2012.09.046. Epub 2012 Sep 23. Review.

PMID:
23063400
[PubMed - indexed for MEDLINE]
Free Article
8.

Cd(II) and Pb(II) complexes of the polyether ionophorous antibiotic salinomycin.

Ivanova J, Pantcheva IN, Mitewa M, Simova S, Tanabe M, Osakada K.

Chem Cent J. 2011 Sep 9;5(1):52. doi: 10.1186/1752-153X-5-52.

PMID:
21906282
[PubMed]
Free PMC Article
9.

Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells.

Fuchs D, Heinold A, Opelz G, Daniel V, Naujokat C.

Biochem Biophys Res Commun. 2009 Dec 18;390(3):743-9. doi: 10.1016/j.bbrc.2009.10.042. Epub 2009 Oct 14.

PMID:
19835841
[PubMed - indexed for MEDLINE]
10.

Synthesis, cytotoxicity and antibacterial activity of new esters of polyether antibiotic - salinomycin.

Antoszczak M, Popiel K, Stefańska J, Wietrzyk J, Maj E, Janczak J, Michalska G, Brzezinski B, Huczyński A.

Eur J Med Chem. 2014 Apr 9;76:435-44. doi: 10.1016/j.ejmech.2014.02.031. Epub 2014 Feb 14.

PMID:
24602789
[PubMed - in process]
11.

Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro.

Lieke T, Ramackers W, Bergmann S, Klempnauer J, Winkler M, Klose J.

BMC Cancer. 2012 Oct 11;12:466. doi: 10.1186/1471-2407-12-466.

PMID:
23057720
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137.

Harvey BM, Mironenko T, Sun Y, Hong H, Deng Z, Leadlay PF, Weissman KJ, Haydock SF.

Chem Biol. 2007 Jun;14(6):703-14.

PMID:
17584617
[PubMed - indexed for MEDLINE]
Free Article
13.

Oxidative Carbon-Carbon Bond Cleavage Is a Key Step in Spiroacetal Biosynthesis in the Fruit Fly Bactrocera cacuminata.

Singh AA, Rowley JA, Schwartz BD, Kitching W, De Voss JJ.

J Org Chem. 2014 Sep 5;79(17):7799-821. doi: 10.1021/jo500791y. Epub 2014 Jul 2.

PMID:
24914610
[PubMed - in process]
14.

Synthesis, antiproliferative and antibacterial activity of new amides of salinomycin.

Antoszczak M, Maj E, Stefańska J, Wietrzyk J, Janczak J, Brzezinski B, Huczyński A.

Bioorg Med Chem Lett. 2014 Apr 1;24(7):1724-9. doi: 10.1016/j.bmcl.2014.02.042. Epub 2014 Feb 25.

PMID:
24631190
[PubMed - in process]
15.

Synthetic modification of a novel microbial ionophore: exploration of anticoccidial structure-activity relationships.

Glazer EA, Koss DA, Olson JA, Ricketts AP, Schaaf TK, Wiscount RJ Jr.

J Med Chem. 1992 May 15;35(10):1839-44.

PMID:
1588562
[PubMed - indexed for MEDLINE]
16.

The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor.

Riccioni R, Dupuis ML, Bernabei M, Petrucci E, Pasquini L, Mariani G, Cianfriglia M, Testa U.

Blood Cells Mol Dis. 2010 Jun 15;45(1):86-92. doi: 10.1016/j.bcmd.2010.03.008. Epub 2010 May 4.

PMID:
20444629
[PubMed - indexed for MEDLINE]
17.

Biosynthetic machinery of ionophore polyether lasalocid: enzymatic construction of polyether skeleton.

Minami A, Oguri H, Watanabe K, Oikawa H.

Curr Opin Chem Biol. 2013 Aug;17(4):555-61. doi: 10.1016/j.cbpa.2013.06.004. Epub 2013 Jun 21. Review.

PMID:
23796908
[PubMed - indexed for MEDLINE]
18.

Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.

Shichijo Y, Migita A, Oguri H, Watanabe M, Tokiwano T, Watanabe K, Oikawa H.

J Am Chem Soc. 2008 Sep 17;130(37):12230-1. doi: 10.1021/ja8040543. Epub 2008 Aug 19.

PMID:
18710235
[PubMed - indexed for MEDLINE]
19.

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.

Ketola K, Hilvo M, Hyötyläinen T, Vuoristo A, Ruskeepää AL, Orešič M, Kallioniemi O, Iljin K.

Br J Cancer. 2012 Jan 3;106(1):99-106. doi: 10.1038/bjc.2011.530.

PMID:
22215106
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.

Lu D, Choi MY, Yu J, Castro JE, Kipps TJ, Carson DA.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7. doi: 10.1073/pnas.1110431108. Epub 2011 Jul 25.

PMID:
21788521
[PubMed - indexed for MEDLINE]
Free PMC Article

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