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Items: 1 to 20 of 125

1.

Enhanced activity of carbosilane dendrimers against HIV when combined with reverse transcriptase inhibitor drugs: searching for more potent microbicides.

Vacas-Córdoba E, Galán M, de la Mata FJ, Gómez R, Pion M, Muñoz-Fernández MÁ.

Int J Nanomedicine. 2014 Jul 29;9:3591-600. doi: 10.2147/IJN.S62673. eCollection 2014.

2.

Synergistic activity profile of carbosilane dendrimer G2-STE16 in combination with other dendrimers and antiretrovirals as topical anti-HIV-1 microbicide.

Sepúlveda-Crespo D, Lorente R, Leal M, Gómez R, De la Mata FJ, Jiménez JL, Muñoz-Fernández MÁ.

Nanomedicine. 2014 Apr;10(3):609-18. doi: 10.1016/j.nano.2013.10.002. Epub 2013 Oct 14.

PMID:
24135563
3.

Synergistic activity of carbosilane dendrimers in combination with maraviroc against HIV in vitro.

Córdoba EV, Arnáiz E, De La Mata FJ, Gómez R, Leal M, Pion M, Muñoz-Fernández MA.

AIDS. 2013 Aug 24;27(13):2053-8. doi: 10.1097/QAD.0b013e328361fa4a.

PMID:
23612005
4.

Development of sulphated and naphthylsulphonated carbosilane dendrimers as topical microbicides to prevent HIV-1 sexual transmission.

Vacas Córdoba E, Arnaiz E, Relloso M, Sánchez-Torres C, García F, Pérez-Álvarez L, Gómez R, de la Mata FJ, Pion M, Muñoz-Fernández MÁ.

AIDS. 2013 May 15;27(8):1219-29. doi: 10.1097/QAD.0b013e32835f2b7a.

PMID:
23925376
5.

Polyanionic carbosilane dendrimer-conjugated antiviral drugs as efficient microbicides: Recent trends and developments in HIV treatment/therapy.

Sepúlveda-Crespo D, Gómez R, De La Mata FJ, Jiménez JL, Muñoz-Fernández MÁ.

Nanomedicine. 2015 Aug;11(6):1481-98. doi: 10.1016/j.nano.2015.03.008. Epub 2015 Mar 31. Review.

PMID:
25835558
6.

Anti-Human Immunodeficiency Virus Activity of Thiol-Ene Carbosilane Dendrimers and Their Potential Development as a Topical Microbicide.

Sánchez-Rodríguez J, Díaz L, Galán M, Maly M, Gómez R, Javier de la Mata F, Jiménez JL, Muñoz-Fernández MA.

J Biomed Nanotechnol. 2015 Oct;11(10):1783-98.

PMID:
26502641
7.

Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1.

Vacas-Córdoba E, Maly M, De la Mata FJ, Gómez R, Pion M, Muñoz-Fernández MÁ.

Int J Nanomedicine. 2016 Apr 5;11:1281-94. doi: 10.2147/IJN.S96352. eCollection 2016.

8.

Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission.

Sepúlveda-Crespo D, Sánchez-Rodríguez J, Serramía MJ, Gómez R, De La Mata FJ, Jiménez JL, Muñoz-Fernández MÁ.

Nanomedicine (Lond). 2015;10(6):899-914. doi: 10.2217/nnm.14.79.

PMID:
25867856
9.

Carbosilane dendrimer nanotechnology outlines of the broad HIV blocker profile.

Chonco L, Pion M, Vacas E, Rasines B, Maly M, Serramía MJ, López-Fernández L, De la Mata J, Alvarez S, Gómez R, Muñoz-Fernández MA.

J Control Release. 2012 Aug 10;161(3):949-58. doi: 10.1016/j.jconrel.2012.04.050. Epub 2012 May 28.

PMID:
22652549
10.

Development of water-soluble polyanionic carbosilane dendrimers as novel and highly potent topical anti-HIV-2 microbicides.

Briz V, Sepúlveda-Crespo D, Diniz AR, Borrego P, Rodes B, de la Mata FJ, Gómez R, Taveira N, Muñoz-Fernández MÁ.

Nanoscale. 2015 Sep 21;7(35):14669-83. doi: 10.1039/c5nr03644e. Epub 2015 Aug 14.

PMID:
26274532
11.

Structure activity relationship of dendrimer microbicides with dual action antiviral activity.

Tyssen D, Henderson SA, Johnson A, Sterjovski J, Moore K, La J, Zanin M, Sonza S, Karellas P, Giannis MP, Krippner G, Wesselingh S, McCarthy T, Gorry PR, Ramsland PA, Cone R, Paull JR, Lewis GR, Tachedjian G.

PLoS One. 2010 Aug 23;5(8):e12309. doi: 10.1371/journal.pone.0012309.

12.

Efficacy of HIV antiviral polyanionic carbosilane dendrimer G2-S16 in the presence of semen.

Ceña-Diez R, García-Broncano P, de la Mata FJ, Gómez R, Muñoz-Fernández MÁ.

Int J Nanomedicine. 2016 May 30;11:2443-50. doi: 10.2147/IJN.S104292. eCollection 2016.

13.

Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16.

Sepúlveda-Crespo D, Serramía MJ, Tager AM, Vrbanac V, Gómez R, De La Mata FJ, Jiménez JL, Muñoz-Fernández MÁ.

Nanomedicine. 2015 Aug;11(6):1299-308. doi: 10.1016/j.nano.2015.04.013. Epub 2015 May 8.

PMID:
25959924
14.

Antiviral properties against HIV of water soluble copper carbosilane dendrimers and their EPR characterization.

Galan M, Sanchez-Rodriguez J, Cangiotti M, Garcia-Gallego S, Jimenez JL, Gomez R, Ottaviani MF, Munoz-Fernandez MA, de la Mata FJ.

Curr Med Chem. 2012;19(29):4984-94.

PMID:
22963631
15.

Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1.

Telwatte S, Moore K, Johnson A, Tyssen D, Sterjovski J, Aldunate M, Gorry PR, Ramsland PA, Lewis GR, Paull JR, Sonza S, Tachedjian G.

Antiviral Res. 2011 Jun;90(3):195-9. doi: 10.1016/j.antiviral.2011.03.186. Epub 2011 Apr 1.

16.

Synthesis of new anionic carbosilane dendrimers via thiol-ene chemistry and their antiviral behaviour.

Galán M, Sánchez Rodríguez J, Jiménez JL, Relloso M, Maly M, de la Mata FJ, Muñoz-Fernández MA, Gómez R.

Org Biomol Chem. 2014 May 28;12(20):3222-37. doi: 10.1039/c4ob00162a. Epub 2014 Apr 14.

PMID:
24728319
17.

Combinations of 3-hydroxyphthalic anhydride-modified ovalbumin with antiretroviral drug-based microbicide candidates display synergistic and complementary effects against HIV-1 infection.

Li L, Tan S, Lu H, Lu L, Yang J, Jin H, Liu S, Jiang S.

J Acquir Immune Defic Syndr. 2011 Apr 15;56(5):384-92. doi: 10.1097/QAI.0b013e31820a4a8d.

18.

Clinical development of microbicides for the prevention of HIV infection.

D'Cruz OJ, Uckun FM.

Curr Pharm Des. 2004;10(3):315-36. Review.

PMID:
14754390
19.

Prevention of vaginal and rectal herpes simplex virus type 2 transmission in mice: mechanism of antiviral action.

Ceña-Diez R, Vacas-Córdoba E, García-Broncano P, de la Mata FJ, Gómez R, Maly M, Muñoz-Fernández MÁ.

Int J Nanomedicine. 2016 May 19;11:2147-62. doi: 10.2147/IJN.S95301. eCollection 2016.

20.

Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission.

Ariën KK, Venkatraj M, Michiels J, Joossens J, Vereecken K, Van der Veken P, Abdellati S, Cuylaerts V, Crucitti T, Heyndrickx L, Heeres J, Augustyns K, Lewi PJ, Vanham G.

J Antimicrob Chemother. 2013 Sep;68(9):2038-47. doi: 10.1093/jac/dkt166. Epub 2013 May 3.

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