Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 102

1.

Mouse hepatocyte overexpression of NF-κB-inducing kinase (NIK) triggers fatal macrophage-dependent liver injury and fibrosis.

Shen H, Sheng L, Chen Z, Jiang L, Su H, Yin L, Omary MB, Rui L.

Hepatology. 2014 Dec;60(6):2065-76. doi: 10.1002/hep.27348. Epub 2014 Oct 29.

2.

Carboxyl terminus of HSC70-interacting protein (CHIP) down-regulates NF-κB-inducing kinase (NIK) and suppresses NIK-induced liver injury.

Jiang B, Shen H, Chen Z, Yin L, Zan L, Rui L.

J Biol Chem. 2015 May 1;290(18):11704-14. doi: 10.1074/jbc.M114.635086. Epub 2015 Mar 19.

3.

Hepatocyte-specific IKK gamma/NEMO expression determines the degree of liver injury.

Beraza N, Lüdde T, Assmus U, Roskams T, Vander Borght S, Trautwein C.

Gastroenterology. 2007 Jun;132(7):2504-17. Epub 2007 Apr 6.

PMID:
17570222
4.

Cooperation of liver cells in health and disease.

Kmieć Z.

Adv Anat Embryol Cell Biol. 2001;161:III-XIII, 1-151. Review.

PMID:
11729749
5.

Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation.

Sunami Y, Leithäuser F, Gul S, Fiedler K, Güldiken N, Espenlaub S, Holzmann KH, Hipp N, Sindrilaru A, Luedde T, Baumann B, Wissel S, Kreppel F, Schneider M, Scharffetter-Kochanek K, Kochanek S, Strnad P, Wirth T.

Hepatology. 2012 Sep;56(3):1117-28. doi: 10.1002/hep.25711. Epub 2012 Jul 10.

PMID:
22407857
6.

Decoding cell death signals in liver inflammation.

Brenner C, Galluzzi L, Kepp O, Kroemer G.

J Hepatol. 2013 Sep;59(3):583-94. doi: 10.1016/j.jhep.2013.03.033. Epub 2013 Apr 6. Review.

7.

NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action.

Sheng L, Zhou Y, Chen Z, Ren D, Cho KW, Jiang L, Shen H, Sasaki Y, Rui L.

Nat Med. 2012 Jun;18(6):943-9. doi: 10.1038/nm.2756.

8.

Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice.

Imose M, Nagaki M, Naiki T, Osawa Y, Brenner DA, Asano T, Hayashi H, Kato T, Moriwaki H.

Liver Int. 2003 Oct;23(5):386-96.

PMID:
14708901
9.

Wnt/β-catenin signaling protects mouse liver against oxidative stress-induced apoptosis through the inhibition of forkhead transcription factor FoxO3.

Tao GZ, Lehwald N, Jang KY, Baek J, Xu B, Omary MB, Sylvester KG.

J Biol Chem. 2013 Jun 14;288(24):17214-24. doi: 10.1074/jbc.M112.445965. Epub 2013 Apr 25.

10.

Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice.

Osawa Y, Seki E, Adachi M, Suetsugu A, Ito H, Moriwaki H, Seishima M, Nagaki M.

Hepatology. 2010 Jan;51(1):237-45. doi: 10.1002/hep.23262.

PMID:
19821528
11.

Inflammatory pathways in liver homeostasis and liver injury.

Tacke F, Luedde T, Trautwein C.

Clin Rev Allergy Immunol. 2009 Feb;36(1):4-12. doi: 10.1007/s12016-008-8091-0. Review.

PMID:
18600481
12.

Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury.

Luedde T, Assmus U, Wüstefeld T, Meyer zu Vilsendorf A, Roskams T, Schmidt-Supprian M, Rajewsky K, Brenner DA, Manns MP, Pasparakis M, Trautwein C.

J Clin Invest. 2005 Apr;115(4):849-59. Epub 2005 Mar 17.

13.

Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1.

Yang L, Inokuchi S, Roh YS, Song J, Loomba R, Park EJ, Seki E.

Gastroenterology. 2013 May;144(5):1042-1054.e4. doi: 10.1053/j.gastro.2013.01.056. Epub 2013 Feb 4.

14.

Reactive oxygen species mediate human hepatocyte injury during hypoxia/reoxygenation.

Bhogal RH, Curbishley SM, Weston CJ, Adams DH, Afford SC.

Liver Transpl. 2010 Nov;16(11):1303-13. doi: 10.1002/lt.22157.

15.

Negative feedback regulation of NF-κB-inducing kinase is proteasome-dependent but does not require cellular inhibitors of apoptosis.

Gray CM, McCorkell KA, Chunduru SK, McKinlay MA, May MJ.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):341-6. doi: 10.1016/j.bbrc.2014.05.122. Epub 2014 Jun 2.

16.

Hepatocyte-specific NEMO deletion promotes NK/NKT cell- and TRAIL-dependent liver damage.

Beraza N, Malato Y, Sander LE, Al-Masaoudi M, Freimuth J, Riethmacher D, Gores GJ, Roskams T, Liedtke C, Trautwein C.

J Exp Med. 2009 Aug 3;206(8):1727-37. doi: 10.1084/jem.20082152. Epub 2009 Jul 27.

17.

NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.

Chung S, Sundar IK, Hwang JW, Yull FE, Blackwell TS, Kinnula VL, Bulger M, Yao H, Rahman I.

PLoS One. 2011;6(8):e23488. doi: 10.1371/journal.pone.0023488. Epub 2011 Aug 24.

18.

Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis.

Hammerich L, Bangen JM, Govaere O, Zimmermann HW, Gassler N, Huss S, Liedtke C, Prinz I, Lira SA, Luedde T, Roskams T, Trautwein C, Heymann F, Tacke F.

Hepatology. 2014 Feb;59(2):630-42. doi: 10.1002/hep.26697. Epub 2013 Dec 23.

19.

PTEN-mediated Akt/β-catenin/Foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury.

Kamo N, Ke B, Busuttil RW, Kupiec-Weglinski JW.

Hepatology. 2013 Jan;57(1):289-98. doi: 10.1002/hep.25958. Epub 2012 Dec 4.

20.

Neuropeptide PACAP in mouse liver ischemia and reperfusion injury: immunomodulation by the cAMP-PKA pathway.

Ji H, Zhang Y, Shen XD, Gao F, Huang CY, Abad C, Busuttil RW, Waschek JA, Kupiec-Weglinski JW.

Hepatology. 2013 Mar;57(3):1225-37. doi: 10.1002/hep.25802. Epub 2013 Jan 18.

Items per page

Supplemental Content

Write to the Help Desk